Detalhe da pesquisa
1.
Mechanistic study of Uba5 enzyme and the Ufm1 conjugation pathway.
J Biol Chem
; 289(33): 22648-22658, 2014 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24966333
2.
Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analogues.
J Biol Chem
; 286(47): 40867-77, 2011 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21969368
3.
Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction.
Nat Commun
; 10(1): 1402, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30926793
4.
A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
Nat Med
; 24(2): 186-193, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29334375
5.
Application and analysis of the GFPu family of ubiquitin-proteasome system reporters.
Methods Enzymol
; 399: 481-90, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16338377
6.
Treatment-emergent mutations in NAEß confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.
Cancer Cell
; 21(3): 388-401, 2012 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22439935
7.
Intersecting pathways to neurodegeneration in Parkinson's disease: effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system.
Neurobiol Dis
; 22(2): 404-20, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16439141
8.
Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation.
Mol Cell
; 17(3): 351-65, 2005 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15694337
9.
Formation of morphologically similar globular aggregates from diverse aggregation-prone proteins in mammalian cells.
Proc Natl Acad Sci U S A
; 102(31): 10887-92, 2005 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16040812
10.
A rhodopsin mutant linked to autosomal dominant retinitis pigmentosa is prone to aggregate and interacts with the ubiquitin proteasome system.
J Biol Chem
; 277(37): 34150-60, 2002 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-12091393