Detalhe da pesquisa
1.
Robust use of phenotypic heterogeneity at drug target genes for mechanistic insights: Application of cis-multivariable Mendelian randomization to GLP1R gene region.
Genet Epidemiol
; 48(4): 151-163, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38379245
2.
Safety and effectiveness of SGLT2 inhibitors in a UK population with type 2 diabetes and aged over 70 years: an instrumental variable approach.
Diabetologia
; 2024 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38836934
3.
Phenotype-based targeted treatment of SGLT2 inhibitors and GLP-1 receptor agonists in type 2 diabetes.
Diabetologia
; 67(5): 822-836, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38388753
4.
Weak and pleiotropy robust sex-stratified Mendelian randomization in the one sample and two sample settings.
Genet Epidemiol
; 47(2): 135-151, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36682072
5.
Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone.
Pharmacogenomics J
; 24(3): 12, 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38632276
6.
Smoking during pregnancy and its effect on placental weight: a Mendelian randomization study.
BMC Pregnancy Childbirth
; 24(1): 238, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38575863
7.
The Triangulation WIthin a STudy (TWIST) framework for causal inference within pharmacogenetic research.
PLoS Genet
; 17(9): e1009783, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34495953
8.
Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments.
PLoS Genet
; 17(6): e1009575, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34157017
9.
Exploiting collider bias to apply two-sample summary data Mendelian randomization methods to one-sample individual level data.
PLoS Genet
; 17(8): e1009703, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34370750
10.
Dirichlet process mixture models to impute missing predictor data in counterfactual prediction models: an application to predict optimal type 2 diabetes therapy.
BMC Med Inform Decis Mak
; 24(1): 12, 2024 01 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38191403
11.
SLCO1B1 Exome Sequencing and Statin Treatment Response in 64,000 UK Biobank Patients.
Int J Mol Sci
; 25(8)2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38674010
12.
Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study.
BMC Med
; 21(1): 355, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37710313
13.
Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study.
BMC Med
; 21(1): 501, 2023 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110912
14.
Mendelian randomisation study of body composition and depression in people of East Asian ancestry highlights potential setting-specific causality.
BMC Med
; 21(1): 37, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36726144
15.
Calcium-channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients.
Br J Clin Pharmacol
; 89(2): 853-864, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36134646
16.
Association between circadian physical activity patterns and mortality in the UK Biobank.
Int J Behav Nutr Phys Act
; 20(1): 102, 2023 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37653438
17.
Mendelian randomisation with coarsened exposures.
Genet Epidemiol
; 45(3): 338-350, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33527565
18.
Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer.
Cancer Causes Control
; 33(5): 631-652, 2022 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-35274198
19.
Profile-likelihood Bayesian model averaging for two-sample summary data Mendelian randomization in the presence of horizontal pleiotropy.
Stat Med
; 41(6): 1100-1119, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35060160
20.
Sensitivity to missing not at random dropout in clinical trials: Use and interpretation of the trimmed means estimator.
Stat Med
; 41(8): 1462-1481, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35098576