Detalhe da pesquisa
1.
I-Ag7 ß56/57 polymorphisms regulate non-cognate negative selection to CD4+ T cell orchestrators of type 1 diabetes.
Nat Immunol
; 24(4): 652-663, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36807641
2.
Transcriptional and chromatin profiling of human blood innate lymphoid cell subsets sheds light on HIV-1 pathogenesis.
EMBO J
; 42(16): e114153, 2023 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37382276
3.
Humanized immune system mouse models: progress, challenges and opportunities.
Nat Immunol
; 20(7): 770-774, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31160798
4.
Simultaneous evaluation of treatment efficacy and toxicity for bispecific T-cell engager therapeutics in a humanized mouse model.
FASEB J
; 37(6): e22995, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37219526
5.
Prostaglandin E2 stimulates cAMP signaling and resensitizes human leukemia cells to glucocorticoid-induced cell death.
Blood
; 137(4): 500-512, 2021 01 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33507291
6.
Enhanced development of functional human NK cells in NOD-scid-IL2rgnull mice expressing human IL15.
FASEB J
; 36(9): e22476, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35959876
7.
An RNAi therapeutic targeting hepatic DGAT2 in a genetically obese mouse model of nonalcoholic steatohepatitis.
Mol Ther
; 30(3): 1329-1342, 2022 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34774753
8.
Prosurvival kinase PIM2 is a therapeutic target for eradication of chronic myeloid leukemia stem cells.
Proc Natl Acad Sci U S A
; 116(21): 10482-10487, 2019 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31068472
9.
A rapid, sensitive, and reproducible in vivo PBMC humanized murine model for determining therapeutic-related cytokine release syndrome.
FASEB J
; 34(9): 12963-12975, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32772418
10.
Human Anti-HIV-1 gp120 Monoclonal Antibodies with Neutralizing Activity Cloned from Humanized Mice Infected with HIV-1.
J Immunol
; 202(3): 799-804, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30593536
11.
Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim.
J Immunol
; 202(3): 647-651, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30610162
12.
Lack of acute xenogeneic graft- versus-host disease, but retention of T-cell function following engraftment of human peripheral blood mononuclear cells in NSG mice deficient in MHC class I and II expression.
FASEB J
; 33(3): 3137-3151, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30383447
13.
Humanized mouse models of immunological diseases and precision medicine.
Mamm Genome
; 30(5-6): 123-142, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30847553
14.
AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice.
Int Arch Allergy Immunol
; 180(2): 91-102, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31401630
15.
Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy.
FASEB J
; 32(3): 1537-1549, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146734
16.
Survival Advantage of Both Human Hepatocyte Xenografts and Genome-Edited Hepatocytes for Treatment of α-1 Antitrypsin Deficiency.
Mol Ther
; 25(11): 2477-2489, 2017 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29032169
17.
The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.
J Immunol
; 195(7): 3011-9, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26283479
18.
Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.
J Allergy Clin Immunol
; 138(3): 769-779, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27139822
19.
Genetically modified human CD4(+) T cells can be evaluated in vivo without lethal graft-versus-host disease.
Immunology
; 148(4): 339-51, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27124592
20.
c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Blood
; 123(7): 1040-50, 2014 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24394663