Detalhe da pesquisa
1.
A clinical review of inhalation anesthesia with sevoflurane: from early research to emerging topics.
J Anesth
; 31(5): 764-778, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28585095
2.
Antagonism of supraspinal histamine H3 receptors modulates spinal neuronal activity in neuropathic rats.
J Pharmacol Exp Ther
; 343(1): 13-20, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22729221
3.
Pharmacological properties and procognitive effects of ABT-288, a potent and selective histamine H3 receptor antagonist.
J Pharmacol Exp Ther
; 343(1): 233-45, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22815533
4.
Discovery of histamine H3 antagonists for the treatment of cognitive disorders and Alzheimer's disease.
J Pharmacol Exp Ther
; 336(1): 38-46, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20864505
5.
In vitro studies on a class of quinoline containing histamine H3 antagonists.
Bioorg Med Chem Lett
; 20(11): 3295-300, 2010 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457525
6.
Rigidified 2-aminopyrimidines as histamine H4 receptor antagonists: effects of substitution about the rigidifying ring.
Bioorg Med Chem Lett
; 20(6): 1900-4, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20171098
7.
A robust and high-capacity [(35)S]GTPgammaS binding assay for determining antagonist and inverse agonist pharmacological parameters of histamine H(3) receptor ligands.
Assay Drug Dev Technol
; 6(3): 339-49, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18593375
8.
The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons.
Neurochem Int
; 53(3-4): 79-88, 2008 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-18590784
9.
Analgesic activity of metabotropic glutamate receptor 1 antagonists on spontaneous post-operative pain in rats.
Eur J Pharmacol
; 580(3): 314-21, 2008 Feb 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18054908
10.
Fatty acid amide hydrolase inhibitors display broad selectivity and inhibit multiple carboxylesterases as off-targets.
Neuropharmacology
; 52(4): 1095-105, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17217969
11.
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity.
Biochem Pharmacol
; 73(8): 1243-55, 2007 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17371699
12.
Dopamine D4 receptor signaling in the rat paraventricular hypothalamic nucleus: Evidence of natural coupling involving immediate early gene induction and mitogen activated protein kinase phosphorylation.
Neuropharmacology
; 50(5): 521-31, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16324724
13.
1-aryl-3-(4-pyridine-2-ylpiperazin-1-yl)propan-1-one oximes as potent dopamine D4 receptor agonists for the treatment of erectile dysfunction.
J Med Chem
; 49(17): 5093-109, 2006 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-16913699
14.
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction.
J Med Chem
; 49(25): 7450-65, 2006 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-17149874
15.
Electrophysiological and in vivo characterization of A-317567, a novel blocker of acid sensing ion channels.
Pain
; 117(1-2): 88-96, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16061325
16.
Antidepressant-like effect of D(2/3) receptor-, but not D(4) receptor-activation in the rat forced swim test.
Neuropsychopharmacology
; 30(7): 1257-68, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15688083
17.
2-[4-(3,4-Dimethylphenyl)piperazin-1-ylmethyl]-1H benzoimidazole (A-381393), a selective dopamine D4 receptor antagonist.
Neuropharmacology
; 49(1): 112-21, 2005 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15992586
18.
Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists.
J Med Chem
; 48(23): 7374-88, 2005 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16279797
19.
A-412997 is a selective dopamine D4 receptor agonist in rats.
Pharmacol Biochem Behav
; 82(1): 140-7, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16153699
20.
Dopamine D2, but not D4, receptor agonists are emetogenic in ferrets.
Pharmacol Biochem Behav
; 81(1): 211-9, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15894081