Detalhe da pesquisa
1.
Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis.
Int J Mol Sci
; 23(2)2022 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35055042
2.
Dual Blockade of Interleukin-1ß and Interleukin-17A Reduces Murine Arthritis Pathogenesis but Also Leads to Spontaneous Skin Infections in Nonhuman Primates.
J Pharmacol Exp Ther
; 364(3): 474-484, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311111
3.
Anti-TNF Thioester Glucocorticoid Antibody-Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model.
J Med Chem
; 67(11): 9495-9515, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38780432
4.
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
Sci Transl Med
; 16(739): eadd8936, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507467
5.
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
J Med Chem
; 66(17): 12544-12558, 2023 09 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37656698
6.
Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis.
Adv Rheumatol
; 62(1): 17, 2022 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35624488
7.
Quantitative in vivo micro-computed tomography for monitoring disease activity and treatment response in a collagen-induced arthritis mouse model.
Sci Rep
; 12(1): 2863, 2022 02 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35190580
8.
Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads.
J Med Chem
; 65(6): 4500-4533, 2022 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35133822
9.
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate.
J Med Chem
; 65(23): 15893-15934, 2022 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36394224
10.
The Bcl-2 family antagonist ABT-737 significantly inhibits multiple animal models of autoimmunity.
J Immunol
; 182(12): 7482-9, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19494271
11.
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin.
Nat Biotechnol
; 25(11): 1290-7, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17934452
12.
Correction to "Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads".
J Med Chem
; 66(8): 6011, 2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37058612
13.
Correction to "Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate".
J Med Chem
; 66(8): 6010, 2023 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37027784
14.
Continuous IL-23 stimulation drives ILC3 depletion in the upper GI tract and, in combination with TNFα, induces robust activation and a phenotypic switch of ILC3.
PLoS One
; 12(8): e0182841, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28792532
15.
Fibronectin extra domain A as a drug delivery targeting epitope for rheumatoid arthritis
Adv Rheumatol
; 62: 17, 2022. graf
Artigo
em Inglês
|
LILACS-Express
| ID: biblio-1519965
16.
Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease.
J Crohns Colitis
; 10(1): 69-76, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26429698