Toward a quasiphase transition in the single-file chain of water molecules: Simple lattice model.

Recently, Ma et al. [Phys. Rev. Lett. 118, 027402 (2017)] have suggested that water molecules encapsulated in (6,5) single-wall carbon nanotube experience a temperature-induced quasiphase transition around 150 K interpreted as changes in the water dipoles orientation. We discuss further this temperature-driven quasiphase transition performing quantum chemical calculations and molecular dynamics simulations and, most importantly, suggesting a simple lattice model to reproduce the properties of the one-dimensional confined finite arrays of water molecules. The lattice model takes into account not only the short-range and long-range interactions but also the rotations in a narrow tube, and both ingredients provide an explanation for a temperature-driven orientational ordering of the water molecules, which persists within a relatively wide temperature range.

Military field training exercise with prolonged physical activity and sleep restriction causes hormonal imbalance in firefighter cadets.

PURPOSE: To evaluate the impact of the "Search and rescue" field military training exercise (SR_FTX) on hormonal modulation and identify their possible correlation with physical and cognitive performance. METHODS: An observational (before and after) study was carried out, with male firefighters cadets (n = 42; age = 23[22;27] years) undergoing a nine-day military exercise (SR_FTX). The Countermovement jump (physical performance), the Stroop test (cognitive alertness), and blood tests for testosterone, cortisol, GH, and IGF-1 were applied. Wilcoxon for paired samples and Spearman's correlation tests were used. RESULTS: Testosterone (751.10 [559.10;882.8] vs. 108.40 [80.12;156.40] ng/dL) and IGF-1 (217.5 [180;239.30] vs. 105 [93;129] ng/mL) significantly decreased while GH (0.10 [0.06;0.18] vs. 1.10 [0.58;2.28] ng/mL) and cortisol (9.60 [8.20;11.55] vs. 15.55 [12.28;18.98] ug/dL) significantly increased. Physical performance (31.2 [30.04;35.4] vs. 21.49 [19,02;23,59] cm) and cognitive alertness were significantly worse after SR_FTX (Congruent task: 1,78 (0183) vs. 1,56 (0185) response/s and incongruous task: 1,23 (0191) vs. 1,02 (0207) response/s). The physical performance showed a strong correlation with testosterone (rho = 0.694) and regular correlations with both IGF-1 (rho = 0.598) and cortisol (rho = - 0.580). The Stroop test presented weak correlations with GH (rho = - 0.350) and cortisol (rho = - 0.361). CONCLUSION: SR_FTX negatively impacted hormonal modulation, physical and cognitive performance. These findings could help commanders decide to replace the employed firefighters in a real mission more frequently. Also, if the real scenario allows, they could think about providing better work conditions, such as improving caloric intake and rest periods, to preserve the military performance and health.

Clinical indicators of nursing outcomes classification for patient with risk for perioperative positioning injury: A cohort study.

AIMS AND OBJECTIVES: To test the validity and reliability of Nursing Outcomes Classification outcomes and their clinical indicators for patients with the nursing diagnosis 'Risk for perioperative positioning injury'. BACKGROUND: Surgical positioning is an essential part of perioperative nursing practice. The use of a standardised language values the clinical evaluation of the perioperative nurse, reinforcing its contribution to surgical patient care. DESIGN: Longitudinal concept validation cohort study. METHODS: Patients were selected based on the operating room surgical schedule. The sample included adult patients who underwent elective surgical procedures requiring anaesthesia, classified as surgical class 2, 3 or 4. Outcomes were measured with an instrument, which included 33 clinical indicators for eight outcomes. The patients were assessed at five distinct time points in the perioperative phases. This study followed the STROBE guidelines. RESULTS: A total of 50 patients were included. Each underwent five clinical assessments, for a total of 250 documented assessments. Differences in evaluations were mostly related to reduced scores of clinical indicators in the immediate postsurgical time points, which recovered to the highest score at the end of the fifth (and last) evaluation. The results of factor analysis and Cronbach's alpha calculations suggested a new configuration for this nursing outcomes, consisting of five outcomes-Circulation Status, Tissue Perfusion: peripheral, Neurological Status: peripheral, Tissue Integrity: skin and mucous membranes and Thermoregulation-and 13 clinical indicators. CONCLUSIONS: Nursing Outcomes Classification outcomes and clinical indicators for the nursing diagnosis at 'Risk for perioperative positioning injury' are sensitive to patient states during the perioperative period. RELEVANCE TO CLINICAL PRACTICE: Use of nursing taxonomies during the perioperative period may contribute to the discussion on the role of perioperative nurses and their relevance in patient care.

Frequency of Toxocara canis antibodies in Mexican paediatric patients with epilepsy.

The relationship between epilepsy and the presence of visceral larva migrans caused by Toxocara canis in Mexican children remains uncertain; however, this relationship needs to be elucidated because these parasite larvae can invade the human central nervous system. Accordingly, this study aimed to determine the frequency and specificity of anti-T. canis antibodies in the sera of children with epilepsy to determine the relationship between this parasite and epilepsy. The sera samples of 214 children were examined: 111 children diagnosed with epilepsy and 103 clinically healthy children without neurological disorders. In the sera of each group, the presence and specificity of anti-T. canis and anti-Ascaris lumbricoides antibodies, as well as the cross-reactivity between them, were assessed using enzyme-linked immunosorbent assay and Western blotting analysis. Among the children with epilepsy, 25.2% exhibited seropositivity to T. canis. Cross-reactivity against the A. lumbricoides antigen was present in 46.8% of the children with epilepsy, whereas 11.7% of the children with epilepsy and anti-T. canis antibodies did not exhibit cross-reactivity against this antigen. The Western blotting analysis of the sera from the children with epilepsy demonstrated the presence of T. canis proteins, with molecular weights of 24, 35, 55, 70, 120 and 210 kDa, and A lumbricoides proteins with molecular weights of 70, 80 and 110 kDa. Our results revealed the presence of anti-T. canis antibodies in the children with epilepsy; furthermore, cross-reactivity tests with A. lumbricoides showed the importance of the presence of anti-T. canis antibodies in revealing the relationship between this parasite and epilepsy in children.

Nonsyndromic cleft lip and palate, gastric cancer and tooth agenesis.

BACKGROUND: To determine the frequency of nonsyndromic cleft lip and/or palate (NSCL/P) in first-degree relatives and to analyze the prevalence of tooth agenesis in patients with gastric cancer. MATERIAL AND METHODS: This cross-sectional, observational, case-control study included 798 patients attended at hospital Santa Casa in Montes Claros, Minas Gerais and Alfa Institute of Gastroenterology of the Federal University of the Minas Gerais. Information on basic demographic data and tooth agenesis of both groups and their family history of NSCL/P in first-degree relatives were evaluated. The collected information was stored in a database and analyzed using statistical program SPSS version 21.0 and the values with p<0.05 were considered statistically significant. RESULTS: Of the 798 patients, 113 (14.16%) consisted of the case group and 685 of the control group (85.84%). Non-Caucasian males were the most affected, although no differences among the groups were detected. Of all participants (n=798), 66 (8.27%) presented tooth agenesis and 25 (3.13%) presented oral cleft in first degree relative. CONCLUSIONS: Our results no found increase in the frequency of tooth agenesis in patients with gastric cancer and in the frequency of NSCL/P in the first-degree relatives of patients with gastric cancer.

Evaluation of waste biomasses and their biochars for removal of polycyclic aromatic hydrocarbons.

This work evaluates the use of biomasses and their biochars as adsorbents to remove polycyclic aromatic hydrocarbons from water. Coconut waste (CW) and orange waste (OW) were pyrolyzed at 350 °C to produce the corresponding biochars (BCW and BOW). Adsorption tests using a mixed solution of benzo(a)anthracene, benzo(b)fluoranthene, benzo(k)fluoranthene, benzo(a)pyrene, and dibenzo(a,h)anthracene showed removal percentages of 30.33-83.43% (CW), 47.09-83.02% (BCW), 24.20-74.25% (OW), and 23.84-84.02% (BOW). The adsorption mechanisms appeared to involve π-π interactions of similar groups of the adsorbate and adsorbent, together with hydrophobic effects. There was no indication of competition between the PAHs for the adsorption sites, and there was evidence of cooperative adsorption. The PAHs could be desorbed from the adsorbents with efficiencies in the range 34.88-72.32%, and the reuse of the adsorbents in two further cycles demonstrated their potential for use in the removal of PAHs from water.

Land application of municipal landfill leachate: fate of ions and ammonia volatilization.

Landfill leachates are pollutants rich in ammoniacal N, Na, and K, but land application potentially offers an alternative for recycling these leachate nutrients. We applied landfill leachate corresponding to 0, 110, 220, 330, and 440 kg ha of total N, divided in three applications (July, August, and October 2008), onto the surface of an acidic (pH 5.5-6.0) clay (79% clay) Ultisol and monitored NH volatilization just after applications and microbiological (0-10 cm) and chemical attributes (0-60-cm soil depth) in August 2008, January 2009, and May 2009. Ammonium (up to 30 mg kg), NO (up to 160 mg kg), Na, K (up to 1.1 cmol kg each), and electrical conductivity (up to 1 dS m) increased transiently in soil following applications. Despite >90% of the total leachate N being ammoniacal, NO predominated in the first soil sampling, 14 d after the second application, suggesting fast nitrification, but it decreased in the soil profile thereafter. From 5 to 25% of the total applied N volatilized as NH, with maximum losses within the first 3 d. Applications inhibited (50%) the relative nitrification rate and increased (50%) hot-water-soluble carbohydrates in the soil at the highest rate. No effects were observed on soil microbial biomass C (114-205 mg kg) and activity (5-8 mg CO-C kg d) or on corn grain yields (6349-7233 kg ha). Controlled land application seems to be a viable alternative for landfill leachate management, but NO leaching, NH volatilization, and accumulation of salinizing ions must be monitored in the long term to prevent environmental degradation.

Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells.

Dendritic cells (DCs) are antigen-presenting cells that drive the differentiation of T CD4+ cells into different profiles according to the nature of the antigen or immunomodulator. Propolis is a resinous product made by bees that has numerous pharmacological properties, including an immunomodulatory action. To assess whether propolis can modulate the activation of CD4+ T cells by stimulating DCs with heat-labile enterotoxin B subunit (EtxB) or lipopolysaccharide (LPS), we aimed to elucidate the mechanisms affected by propolis in the differential activation of T lymphocytes. Cell viability, lymphocyte proliferation, gene expression (GATA-3 and RORc), and cytokine production (interleukin (IL)-4 and IL-17A) were analyzed. Propolis, EtxB, and LPS induced a higher lymphoproliferation compared with the control. Propolis induced GATA-3 expression and, in combination with EtxB, maintained the baseline levels. Propolis alone or in combination with LPS inhibited RORc expression. EtxB alone and in combination with propolis increased IL-4 production. Propolis in combination with LPS prevented LPS-induced IL-17A production. These results opened perspectives for the study of biological events that may be favored by propolis by promoting Th2 activation or helping in the treatment of inflammatory conditions mediated by Th17 cells.

Agronomic parameters of sugarcane under planting densities in different cultivation cycles.

Low density sugarcane plantation (LDSP) has been implemented by some sugarcane producers in Brazil, aiming to save seeds and operational costs. The study was carried out in the municipality of Areia, Paraíba, Brazil. Five planting densities were used, varying from 5 to 25 m-2 of buds arranged in randomized blocks, with four replications. Data were measured annually over three cultivation cycles (2017 to 2020), during which the field was fertilized with NPK and the harvests were carried out manually without prior burning. The lower planting density presents higher productivity only in the cane plant (101.03 t ha-1) due to the higher plant height (2.37 m) and the higher number of stalks (11 stalks m-2), suggesting that these variables are due to the greater availability of light, water and photosynthate. However, there is a drastic reduction in sugarcane yield for this lower population in the 2nd ratoon by up to 65.62%, which is correlated with number of stalks per meter. We demonstrate the agronomic viability of LDSP in the population of 10 buds m-2 in relation to conventional planting of sugarcane until the 2nd ratoon. Data are important for future studies to present additional considerations for other production factors, such as the effects of mechanized harvesting and the management of nutrients and water, assessing the sustainability of this large-scale planting system.

Genetic Differentiation of Aedes aegypti (Diptera: Culicidae) in Areas with High Rates of Infestation in Mid-North Region of Brazil.

Aedes aegypti is the principal vector of the arboviruses-yellow fever, dengue virus, chikungunya, and zika virus. Given the epidemiological importance of this mosquito, its capacity to adapt to different habitats, and its resistance to many types of control measures, systematic research into the genetic variability of the populations of this mosquito is one of the most important steps toward a better understanding of its population structure and vector competence. In this context, the present study verified the presence of distinct genetic lineages of Ae. aegypti in areas with high infestation rates, based on the analysis of microsatellite markers. The samples were collected in nine municipalities with high building infestation rates in the Mid-North region of Brazil. Six microsatellite loci were genotyped in the 138 samples, producing a total of 32 alleles, varying from one to nine alleles per locus in each of the different populations. The AMOVA revealed greater within-population genetic differentiation with high fixation rates. The general analysis of population structure, based on a Bayesian approach, revealed K = 2, with two Ae. aegypti lineages that were highly differentiated genetically. These data on the connectivity of the populations and the genetic isolation of the lineages provide important insights for the development of innovative strategies for the control of the populations of this important disease vector.

Burnout Syndrome prevalence among nursing technicians of an Adult Intensive Care Unit.

OBJECTIVE: to verify Burnout Syndrome prevalence among nursing technicians of an adult Intensive Care Unit and associate prevalence with sociodemographic and clinical data. METHOD: a cross-sectional study carried out in an adult Intensive Care Unit of a large public hospital in southern Brazil, between March and April/2018. Prevalence was assessed using the Maslach Burnout Inventory. RESULTS: 122 nursing technicians participated (aged 39±2.5 years), 76% being women. Burnout Syndrome prevalence was 19.7% and 62.9%. There was a significant association between Burnout Syndrome and depression (p=0.004), as well as Burnout Syndrome and comorbidities (p=0.033), when less conservative criteria were adopted. CONCLUSION: the findings are relevant to professionals in this area and may contribute to adopting strategies to combat Burnout Syndrome.

The impact of a low-calorie, low-glycemic diet on systemic lupus erythematosus: a systematic review.

BACKGROUND: Diet plays a critical role in Systemic Lupus Erythematosus (SLE) patients, impacting on the microbiota composition and, consequently, on the immune response. The objective was to analyze and verify the diet effect on SLE patients. METHODS: This is a systematic review performed at the Evidences-based Health Lab, Escola Superior em Ciências da Saúde, Brasília (DF), Brazil. In March, 2021, five databases, and grey literature, through JSTOR, Open Grey, and Google Scholar were searched. Randomized Clinical Trials in which SLE patients with calorie restricted, low glycemic index or other diet involving the joint adequacy of these aspects, compared with placebo or different types of diet, were included. RESULTS: It was identified in the databases 758 articles; 132 were duplicated; 616 references were screened, and 604 were excluded. After reading the title and abstract, 12 articles were included for full-text reading. After the full-text reading, three studies were included for quantitative analysis. The diet improved the quality of life at 6 (MD 16.30; 5.91;26.69) and 12 weeks (MD 14.60; 0.88;28.32). The GRADE was used to evaluate the quality of evidence. CONCLUSION: There is low evidence that the diet has a positive impact on the quality of life of SLE patients. Trial registration PROSPERO-CRD4202012208.

Chronic myeloid leukaemia in two multiple sclerosis patients on interferon beta-1a.

Haematological problems are commonly associated with use of beta-interferon in multiple sclerosis (MS) patients. However these problems are usually benign and are reversible when the drug is stopped. We describe two patients, with the diagnosis of MS, who developed leucocytosis. Cytogenetic studies showed the presence of the Philadelphia chromosome in all the cells analysed, confirming the diagnosis of chronic myeloid leukaemia (CML). The first patient currently on imatimib mesylate and interferon beta-1a is asymptomatic. For the second patient, interferon beta-1a was withdrawn after suspicion of CML.

O controle social em disputa: a reiteração do lugar excluído? / Social control in dispute: the reiteration of the excluded place?

Resumo: As experiências de controle social sobre as ações governamentais despertam a curiosidade científica de vários pesquisadores vinculados à defesa da cidadania. O objetivo desta abordagem é investigar as contribuições e as influências que as pessoas com deficiência exerceram na formulação da política de saúde no Pará. Trata-se de estudo qualitativo, descritivo e analítico. A pesquisa conclui que o grupo pesquisado não desempenhou capacidade política para impor inflexões nas opções governamentais.

Abstract: Experiences of social control over government actions arouse the scientific curiosity of several researchers linked to the defense of citizenship. The objective of this approach is to investigate the contributions and influences that people with disabilities exerted on the formulation of health policy in Pará. This is a qualitative, descriptive and analytical study. The research concludes that the group studied did not have the political capacity to impose changes in government options.

Effect of propolis on Th2 and Th17 cells: interplay with EtxB- and LPS-treated dendritic cells

Dendritic cells (DCs) are antigen-presenting cells that drive the differentiation of T CD4+ cells into different profiles according to the nature of the antigen or immunomodulator. Propolis is a resinous product made by bees that has numerous pharmacological properties, including an immunomodulatory action. To assess whether propolis can modulate the activation of CD4+ T cells by stimulating DCs with heat-labile enterotoxin B subunit (EtxB) or lipopolysaccharide (LPS), we aimed to elucidate the mechanisms affected by propolis in the differential activation of T lymphocytes. Cell viability, lymphocyte proliferation, gene expression (GATA-3 and RORc), and cytokine production (interleukin (IL)-4 and IL-17A) were analyzed. Propolis, EtxB, and LPS induced a higher lymphoproliferation compared with the control. Propolis induced GATA-3 expression and, in combination with EtxB, maintained the baseline levels. Propolis alone or in combination with LPS inhibited RORc expression. EtxB alone and in combination with propolis increased IL-4 production. Propolis in combination with LPS prevented LPS-induced IL-17A production. These results opened perspectives for the study of biological events that may be favored by propolis by promoting Th2 activation or helping in the treatment of inflammatory conditions mediated by Th17 cells.

Feira das Cartas: integrando promoção, regionalização e gestão em saúde em atividade lúdica e interativa / Letters fair: integrating regionalization, health promotion and management in a playful and interactive activity

Resumo Introdução: A educação médica, por meio de metodologias ativas, proporciona o ensino e a aplicação integrada de conceitos da saúde coletiva, como regionalização, promoção e gestão em saúde. Durante a pandemia de Covid-19, ao considerar a necessidade de adaptações de ensino para a manutenção da qualidade do aprendizado, o módulo de Saúde Coletiva III do curso de graduação em Medicina implementou a atividade remota "Feira Virtual das Cartas de Promoção da Saúde", a qual proporcionou o desenvolvimento de habilidades importantes. Dessa maneira, objetiva-se, neste relato, expor o ensino teórico e a aplicação prática integrada dos conceitos e princípios de promoção, regionalização e gestão da saúde, importantes no estudo da saúde coletiva, por meio dessa atividade no ensino remoto. Relato de experiência: A atividade "Feira Virtual das Cartas de Promoção da Saúde", desenvolvida no terceiro período, contou com quatro etapas. A etapa 0 consistiu em um encontro síncrono para que os docentes explicassem aos discentes as demais etapas e o desenvolvimento da atividade. A primeira compreendeu a leitura das "Cartas de Promoção da Saúde" e a confecção de produto ou ação factível, executável e aplicável para apresentarem na feira. A segunda parte foi composta por gerenciamento de recursos fictícios por cada equipe, considerando a qualidade e as necessidades dos produtos ofertados na feira. A última etapa consistiu na avaliação, por meio de feedback, entre docentes e discentes. Discussão: Por meio dessa dinâmica, os discentes aprofundaram seus conhecimentos acerca das "Cartas de Promoção da Saúde" e puderam aplicar, a partir delas, as diretrizes do Sistema Único de Saúde (SUS) em um contexto mais amplo e globalizado. Os estudantes potencializaram suas habilidades de gestão e criatividade, embora algumas limitações tenham sido observadas, como a falta de um conhecimento mais abrangente sobre "gestão em saúde", o qual poderia ter aprimorado o aproveitamento durante a atividade. Conclusão: Os discentes puderam atuar de forma ativa na construção do conhecimento ao longo do processo, desenvolvendo habilidades imprescindíveis para a prática profissional. A atividade, de forma lúdica, proporcionou a integração de diversos conceitos em saúde coletiva, representando um exemplo de como a educação médica pode atuar de maneira integrativa e prática.

Abstract Introduction: Medical education, through active methodologies, provides the teaching and integrated application of Collective Health concepts, such as Regionalization, Health Promotion and Management. During the COVID-19 pandemic, considering the need for adaptations in teaching methods to maintain the quality of learning, the Collective Health Module III of the undergraduate medical course implemented the remote activity "Virtual Fair of Health Promotion Letters", which provided the development of important skills. Thus, the aim of this report is to expose the theoretical teaching and the integrated practical application of the concepts and principles of health promotion, regionalization and health management, which are important in the study of Collective Health, through this remote learning activity. Experience report: The activity "Virtual Fair of Health Promotion Letters", developed in the third term, had 4 stages. Stage zero consisted of a synchronous meeting for the teachers to explain the other stages and the development of the activity to the students. The first stage included reading the "Health Promotion Letters" and making a feasible, executable and applicable product or action to present at the Fair. The second part consisted of each team managing fictitious resources, considering the quality and needs of the products offered at the fair. The final stage was an evaluation based on feedback between teachers and students. Discussion: Through this dynamic, the students deepened their knowledge about the "Health Promotion Letters" and were able to apply the guidelines of the Unified Health System (SUS) in a broader, globalised context. Students enhanced their management and creativity skills, although some limitations were observed, such as the lack of more comprehensive knowledge about "Health management", which could have improved their performance during the activity. Conclusion: The students were able to play an active role in the construction of knowledge throughout the process, developing essential skills for professional practice. The activity, in a playful way, provided the integration of several concepts in Collective Health; representing an example of how medical education can act in an integrative and practical way.

Effects of the LactoSorb bioabsorbable plates on the craniofacial development of rabbits: direct morphometric analysis using linear measurements.

The use of plates for the treatment of fractures can affect craniofacial bone development. This study investigated the effect of bioabsorbable plates and titanium microscrews on the growth of the craniofacial skeleton of rabbits (Oryctolagus cuniculus), in the neonatal period. A LactoSorb plate and PROMM titanium microscrews were positioned across the coronal suture in animals in the study group. In the control group, only PROMM titanium microscrews were attached to the cranium. Anteroposterior linear measurements were obtained using 3 different gauging devices: digital precision caliper, EKG caliper and nylon string. Frontal-nasal (FN) distances were statistically different between the left and right side when the digital caliper (P

Biochemical and hormonal parameters of goats kept in a controlled environment consuming water with different levels of salinity / [Parâmetros bioquímicos e hormonais de caprinos consumindo água com diferentes níveis de salinidade mantidos em ambiente controlado]

The objective of this work was to evaluate the biochemical and hormonal variables of Moxotó and Canindé goats submitted to two temperatures - 26.0±0.6 (thermoneutral) and 32.0±1.2°C (above thermal comfort zone) - and consuming water with three levels of salinity (1.0, 6.0 and 12.0 dSm-1). Thirty-six animals (18 of each breed) were used, with an average age of 5.0±0.6months and an average weight of 20.0±2.3kg, housed in metabolic cages inside a climate chamber. The animals were distributed in a completely randomized design with a 2 × 2 × 3 factorial scheme (2 breeds, 2 temperatures and 3 levels of salinity) and three replications. The glucose and urea had a significant effect (P>0.05) according to water salinity. Glucose, cholesterol, protein, albumin, globulin, aspartate aminotransferase and hormones (T4, T3 and cortisol) varied according to temperature (P<0.05). There was a significant effect of time on hormonal variables (P<0.05). Biochemical and hormonal variables changed according to temperature and day shift, so that metabolism was reduced in the animals under thermal stress and accelerated when animals were in the thermal comfort zone.(AU)

O objetivo do trabalho foi avaliar as variáveis bioquímicas e hormonais de caprinos das raças Moxotó e Canindé, submetidos a duas temperaturas (26,0±0,6ºC e 32,0±1,2ºC), termoneutra e acima da zona de conforto térmico, respectivamente), consumindo água com três níveis de salinidade (1,0, 6,0 e 12,0dSm-1), utilizando-se 36 animais (18 de cada raça), com idade média de 5,0±0,6 meses e peso médio de 20,0±2,3kg, alojados em gaiolas metabólicas no interior de uma câmara climática. Os animais foram distribuídos em um delineamento inteiramente ao acaso, com esquema fatorial de 2 x 2 x 3 (2 raças, 2 temperaturas e 3 níveis de salinidade) e três repetições. A glicose e a ureia apresentaram efeito significativo (P<0,05) em função da salinidade da água. Glicose, colesterol, proteína, albumina, globulina, AST e hormônios (T4, T3 e cortisol) variaram conforme as temperaturas (P<0,05). Observou-se efeito significativo do horário sobre as variáveis hormonais (P<0,05). As variáveis bioquímicas e hormonais sofrem alterações em função da temperatura e do turno do dia, de modo que o metabolismo é reduzido em animais sob estresse térmico e acelerado quando os animais encontram-se na zona de conforto térmico.(AU)

Burnout Syndrome prevalence among nursing technicians of an Adult Intensive Care Unit / Prevalencia de Síndrome de Burnout em técnicos em enfermería de una Unidad de Terapia Intensiva Adulto / Prevalência de esgotamento profissional em técnicos em enfermagem de uma unidade de Terapia Intensiva Adulto

ABSTRACT Objective: to verify Burnout Syndrome prevalence among nursing technicians of an adult Intensive Care Unit and associate prevalence with sociodemographic and clinical data. Method: a cross-sectional study carried out in an adult Intensive Care Unit of a large public hospital in southern Brazil, between March and April/2018. Prevalence was assessed using the Maslach Burnout Inventory. Results: 122 nursing technicians participated (aged 39±2.5 years), 76% being women. Burnout Syndrome prevalence was 19.7% and 62.9%. There was a significant association between Burnout Syndrome and depression (p=0.004), as well as Burnout Syndrome and comorbidities (p=0.033), when less conservative criteria were adopted. Conclusion: the findings are relevant to professionals in this area and may contribute to adopting strategies to combat Burnout Syndrome.

RESUMEN Objetivo: verificar laprevalencia de agotamiento profesional (Síndrome de Burnout) en técnicos de enfermería de una Unidad de Cuidados Intensivos de adultos y asociar la prevalencia con datos sociodemográficos y clínicos. Método: estudio transversal, desarrollado en una unidad de cuidados intensivos para adultos de un gran hospital público delsur de Brasil, entre marzo y abril de 2018. La prevalencia se evaluó mediante el Maslach Burnout Inventory. Resultados: participaron 122 técnicos de enfermería (edad 39±2,5 años), de los cuales 76% eran mujeres. La prevalencia del síndrome de Burnout fue del 19,7% y del 62,9%. Hubo asociación significativa entre Síndrome de Burnout y depresión (p=0,004), así como Síndrome de Burnout y comorbilidades (p=0,033), cuando se adoptó un criterio menos conservador. Conclusión: los hallazgos son relevantes para los profesionales de esta área y pueden contribuir a laadopción de estrategias para combatir el Síndrome de Burnout.

RESUMO Objetivo: verificar a prevalência de esgotamento profissional (Síndrome de Burnout) em técnicos em enfermagem de uma Unidade de Terapia Intensiva adulto e associar a prevalência a dados sociodemográficos e clínicos. Método: estudo transversal, desenvolvido em Unidade de Terapia Intensiva adulto de hospital público de grande porte do Sul do Brasil, entre março e abril de 2018. A prevalência foi avaliada com o Maslach Burnout Inventory. Resultados: participaram 122 técnicos em enfermagem (idade 39 ± 2,5 anos), sendo 76% mulheres. As prevalências de Síndrome de Burnout foram 19,7% e 62,9%. Houve associação significativa entre Síndrome de Burnout e depressão (p=0,004), assim como Síndrome de Burnout e comorbidades (p=0,033), quando adotado critério menos conservador. Conclusão: os achados são relevantes para os profissionais desta área, podendo contribuir para adoção de estratégias de combate à Síndrome de Burnout.