Detalhe da pesquisa
1.
Hedgehog interacting protein activates sodium-glucose cotransporter 2 expression and promotes renal tubular epithelial cell senescence in a mouse model of type 1 diabetes.
Diabetologia
; 66(1): 223-240, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36260124
2.
Angiotensin II type-2-receptor stimulation ameliorates focal and segmental glomerulosclerosis in mice.
Clin Sci (Lond)
; 136(10): 715-731, 2022 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35502764
3.
Deletion of heterogeneous nuclear ribonucleoprotein F in renal tubules downregulates SGLT2 expression and attenuates hyperfiltration and kidney injury in a mouse model of diabetes.
Diabetologia
; 64(11): 2589-2601, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34370045
4.
AT2R deficiency in mice accelerates podocyte dysfunction in diabetic progeny in a sex-dependent manner.
Diabetologia
; 64(9): 2108-2121, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34047808
5.
Angiotensin II up-regulates sodium-glucose co-transporter 2 expression and SGLT2 inhibitor attenuates Ang II-induced hypertensive renal injury in mice.
Clin Sci (Lond)
; 135(7): 943-961, 2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33822013
6.
High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells.
J Biol Chem
; 290(35): 21603-14, 2015 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26175156
7.
Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-ß1-induced kidney injury in a mouse model of diabetes.
Diabetologia
; 58(10): 2443-54, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26232095
8.
Angiotensin-(1-7) prevents systemic hypertension, attenuates oxidative stress and tubulointerstitial fibrosis, and normalizes renal angiotensin-converting enzyme 2 and Mas receptor expression in diabetic mice.
Clin Sci (Lond)
; 128(10): 649-63, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25495544
9.
Heterogeneous nuclear ribonucleoprotein F deficiency in mouse podocyte promotes podocytopathy mediated by methyltransferase-like 14 nuclear translocation resulting in Sirtuin 1 gene inhibition.
Transl Res
; 267: 1-9, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195017
10.
Overexpression of catalase prevents hypertension and tubulointerstitial fibrosis and normalization of renal angiotensin-converting enzyme-2 expression in Akita mice.
Am J Physiol Renal Physiol
; 304(11): F1335-46, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23552863
11.
NRF2 Deficiency Attenuates Diabetic Kidney Disease in Db/Db Mice via Down-Regulation of Angiotensinogen, SGLT2, CD36, and FABP4 Expression and Lipid Accumulation in Renal Proximal Tubular Cells.
Antioxidants (Basel)
; 12(9)2023 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37760019
12.
Dual RAS blockade normalizes angiotensin-converting enzyme-2 expression and prevents hypertension and tubular apoptosis in Akita angiotensinogen-transgenic mice.
Am J Physiol Renal Physiol
; 302(7): F840-52, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22205225
13.
Advancing Discovery Research in Nephrology in Canada: A Conference Report From the 2021 Molecules and Mechanisms Mediating Kidney Health and Disease (M3K) Scientific Meeting and Investigator Summit.
Can J Kidney Health Dis
; 9: 20543581221144824, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36545249
14.
Reactive oxygen species promote caspase-12 expression and tubular apoptosis in diabetic nephropathy.
J Am Soc Nephrol
; 21(6): 943-54, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20299359
15.
The Rationale and Evidence for SGLT2 Inhibitors as a Treatment for Nondiabetic Glomerular Disease.
Glomerular Dis
; 1(1): 21-33, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36751486
16.
Overexpression of Nrf2 in Renal Proximal Tubular Cells Stimulates Sodium-Glucose Cotransporter 2 Expression and Exacerbates Dysglycemia and Kidney Injury in Diabetic Mice.
Diabetes
; 70(6): 1388-1403, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33820760
17.
Catalase overexpression prevents hypertension and tubular apoptosis in angiotensinogen transgenic mice.
Kidney Int
; 77(12): 1086-97, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20237455
18.
Comparison of the effects of insulin and SGLT2 inhibitor on the Renal Renin-Angiotensin system in type 1 diabetes mice.
Diabetes Res Clin Pract
; 162: 108107, 2020 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-32173417
19.
Increased urinary excretion of hedgehog interacting protein (uHhip) in early diabetic kidney disease.
Transl Res
; 217: 1-10, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794697
20.
Apocynin attenuates tubular apoptosis and tubulointerstitial fibrosis in transgenic mice independent of hypertension.
Kidney Int
; 75(2): 156-66, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18923387