Detalhe da pesquisa
1.
CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion.
Nucleic Acids Res
; 45(11): 6698-6716, 2017 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334900
2.
The clonal and mutational evolution spectrum of primary triple-negative breast cancers.
Nature
; 486(7403): 395-9, 2012 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22495314
3.
A transgenic mouse model demonstrating the oncogenic role of mutations in the polycomb-group gene EZH2 in lymphomagenesis.
Blood
; 123(25): 3914-24, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24802772
4.
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers.
N Engl J Med
; 366(3): 234-42, 2012 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22187960
5.
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.
Blood
; 117(8): 2451-9, 2011 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21190999
6.
Recruitment of a SAP18-HDAC1 complex into HIV-1 virions and its requirement for viral replication.
PLoS Pathog
; 5(6): e1000463, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19503603
7.
The Pathognomonic FOXL2 C134W Mutation Alters DNA-Binding Specificity.
Cancer Res
; 80(17): 3480-3491, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32641414
8.
HIV-1 Tat stimulates transcription complex assembly through recruitment of TBP in the absence of TAFs.
PLoS Biol
; 3(2): e44, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15719058
9.
CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.
Nat Commun
; 8(1): 7, 2017 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28232751
10.
Structures of the CDK12/CycK complex with AMP-PNP reveal a flexible C-terminal kinase extension important for ATP binding.
Sci Rep
; 5: 17122, 2015 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26597175
11.
Interaction of cyclin-dependent kinase 12/CrkRS with cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II.
Mol Cell Biol
; 32(22): 4691-704, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22988298