Detalhe da pesquisa
1.
Loss of stress sensor GADD45A promotes stem cell activity and ferroptosis resistance in LGR4/HOXA9-dependent AML.
Blood
; 2024 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38579286
2.
Inhibition of mitochondrial translocase SLC25A5 and histone deacetylation is an effective combination therapy in neuroblastoma.
Int J Cancer
; 152(7): 1399-1413, 2023 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36346110
3.
Pyrimido[1,2-a]benzimidazoles as inhibitors of oncoproteins ubiquitin specific protease 5 and MYCN in the childhood cancer neuroblastoma.
Bioorg Chem
; 136: 106462, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37060785
4.
Mitotic Dysregulation at Tumor Initiation Creates a Therapeutic Vulnerability to Combination Anti-Mitotic and Pro-Apoptotic Agents for MYCN-Driven Neuroblastoma.
Int J Mol Sci
; 24(21)2023 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37958555
5.
A structural view of PA2G4 isoforms with opposing functions in cancer.
J Biol Chem
; 295(47): 16100-16112, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32952126
6.
CD44 variant 6 is associated with prostate cancer growth and chemo-/radiotherapy response in vivo.
Exp Cell Res
; 388(2): 111850, 2020 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31954695
7.
Synthesis and Characterisation of Novel Tricyclic and Tetracyclic Furoindoles: Biological Evaluation as SAHA Enhancer against Neuroblastoma and Breast Cancer Cells.
Molecules
; 26(19)2021 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34641289
8.
Combination therapy with the CDK7 inhibitor and the tyrosine kinase inhibitor exerts synergistic anticancer effects against MYCN-amplified neuroblastoma.
Int J Cancer
; 147(7): 1928-1938, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32086952
9.
Synthesis, Characterization and Biological Evaluation of Novel Dihydropyranoindoles Improving the Anticancer Effects of HDAC Inhibitors.
Molecules
; 25(6)2020 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32197360
10.
Synthesis, Characterization and Anti-Cancer Activity of Hydrazide Derivatives Incorporating a Quinoline Moiety.
Molecules
; 21(7)2016 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27428941
11.
MYCN and SNRPD3 cooperate to maintain a balance of alternative splicing events that drives neuroblastoma progression.
Oncogene
; 43(5): 363-377, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38049564
12.
TRIM16 overexpression induces apoptosis through activation of caspase-2 in cancer cells.
Apoptosis
; 18(5): 639-51, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23404198
13.
The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro.
J Pathol
; 226(3): 451-62, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22009481
14.
Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface.
Cancers (Basel)
; 15(6)2023 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36980710
15.
Synthesis of retinoid enhancers based on 2-aminobenzothiazoles for anti-cancer therapy.
Bioorg Med Chem
; 20(23): 6877-84, 2012 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23088909
16.
Single-cell profiling of peripheral neuroblastic tumors identifies an aggressive transitional state that bridges an adrenergic-mesenchymal trajectory.
Cell Rep
; 41(1): 111455, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36198269
17.
The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Front Oncol
; 12: 863329, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35677155
18.
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability.
Nat Commun
; 12(1): 1881, 2021 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33767157
19.
MEIS2 Is an Adrenergic Core Regulatory Transcription Factor Involved in Early Initiation of TH-MYCN-Driven Neuroblastoma Formation.
Cancers (Basel)
; 13(19)2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638267
20.
Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires ß-catenin activity to drive T-cell acute lymphoblastic leukemia.
Nat Commun
; 12(1): 4164, 2021 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34230493