Detalhe da pesquisa
1.
N-Heterocyclic Carbene Ligand-Enabled C(sp(3))-H Arylation of Piperidine and Tetrahydropyran Derivatives.
Chemistry
; 22(14): 4748-52, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26841330
2.
Orchestrated triple C-H activation reactions using two directing groups: rapid assembly of complex pyrazoles.
Angew Chem Int Ed Engl
; 54(8): 2501-4, 2015 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641121
3.
Strategies for the modulation of phase II metabolism in a series of PKCε inhibitors.
Bioorg Med Chem Lett
; 24(15): 3398-402, 2014 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24939756
4.
Diastereoselective one-pot Knoevenagel condensation/Corey-Chaykovsky cyclopropanation.
J Org Chem
; 78(2): 780-5, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23252964
5.
Selectivity profiling of novel indene H(1)-antihistamines for the treatment of insomnia.
Bioorg Med Chem Lett
; 20(8): 2629-33, 2010 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20227880
6.
Identification of a novel selective H1-antihistamine with optimized pharmacokinetic properties for clinical evaluation in the treatment of insomnia.
Bioorg Med Chem Lett
; 20(19): 5874-8, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20800486
7.
Novel benzothiophene H1-antihistamines for the treatment of insomnia.
Bioorg Med Chem Lett
; 20(7): 2316-20, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188547
8.
Brain-penetrating 2-aminobenzimidazole H(1)-antihistamines for the treatment of insomnia.
Bioorg Med Chem Lett
; 19(15): 4380-4, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19553115
9.
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
Bioorg Med Chem Lett
; 18(16): 4503-7, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18667310
10.
Validation and application of a liquid chromatography-tandem mass spectrometric method for the simultaneous determination of testosterone and dihydrotestosterone in rat prostatic tissue using a 96-well format.
J Chromatogr B Analyt Technol Biomed Life Sci
; 877(29): 3515-21, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19767251
11.
Characterization of novel selective H1-antihistamines for clinical evaluation in the treatment of insomnia.
J Med Chem
; 52(17): 5307-10, 2009 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19663387