Detalhe da pesquisa
1.
Publisher Correction: A mass spectrometry-based proteome map of drug action in lung cancer cell lines.
Nat Chem Biol
; 16(10): 1149, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32792589
2.
A mass spectrometry-based proteome map of drug action in lung cancer cell lines.
Nat Chem Biol
; 16(10): 1111-1119, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32690943
3.
Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model.
Chembiochem
; 21(13): 1905-1910, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32003101
4.
Monovalent protein-degraders - Insights and future perspectives.
Bioorg Med Chem Lett
; 30(12): 127202, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32331933
5.
Identification of broad-spectrum antiviral compounds and assessment of the druggability of their target for efficacy against respiratory syncytial virus (RSV).
Proc Natl Acad Sci U S A
; 108(17): 6739-44, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21502533
6.
Small molecule Toll-like receptor 7 agonists localize to the MHC class II loading compartment of human plasmacytoid dendritic cells.
Blood
; 117(21): 5683-91, 2011 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21487111
7.
Natural products reveal cancer cell dependence on oxysterol-binding proteins.
Nat Chem Biol
; 7(9): 639-47, 2011 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-21822274
8.
Chemoproteomic profiling to identify activity changes and functional inhibitors of DNA-binding proteins.
Cell Chem Biol
; 29(11): 1639-1648.e4, 2022 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36356585
9.
A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV-1 Infected Cells.
ACS Chem Biol
; 17(9): 2595-2604, 2022 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044633
10.
Rapid Evaluation of Small Molecule Cellular Target Engagement with a Luminescent Thermal Shift Assay.
ACS Med Chem Lett
; 12(8): 1288-1294, 2021 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34413958
11.
Discovery of an Anion-Dependent Farnesyltransferase Inhibitor from a Phenotypic Screen.
ACS Med Chem Lett
; 12(1): 99-106, 2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33488970
12.
Causes and Significance of Increased Compound Potency in Cellular or Physiological Contexts.
J Med Chem
; 61(5): 1767-1773, 2018 03 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28820267
13.
Comparison of the Rat and Human Dorsal Root Ganglion Proteome.
Sci Rep
; 8(1): 13469, 2018 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30194433
14.
Highly potent visnagin derivatives inhibit Cyp1 and prevent doxorubicin cardiotoxicity.
JCI Insight
; 3(1)2018 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29321375
15.
Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
Cell Chem Biol
; 25(6): 705-717.e11, 2018 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29628435
16.
Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2.
ChemMedChem
; 12(12): 917-924, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28371485
17.
Conversion of a Single Polypharmacological Agent into Selective Bivalent Inhibitors of Intracellular Kinase Activity.
ACS Chem Biol
; 11(1): 121-31, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26505072
18.
Potent, Selective, and Orally Bioavailable Inhibitors of VPS34 Provide Chemical Tools to Modulate Autophagy in Vivo.
ACS Med Chem Lett
; 7(1): 72-6, 2016 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26819669
19.
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo.
Nat Cell Biol
; 16(11): 1069-79, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25327288
20.
Kinase inhibitor profiling using chemoproteomics.
Methods Mol Biol
; 795: 161-77, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-21960222