Detalhe da pesquisa
1.
Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study.
Gastroenterology
; 152(5): 1078-1089, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28043905
2.
Three Faces of Mercaptopurine Cytotoxicity In Vitro: Methylation, Nucleotide Homeostasis, and Deoxythioguanosine in DNA.
Drug Metab Dispos
; 46(8): 1191-1199, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29884651
3.
HLA-DRB1*16: 01-DQB1*05: 02 is a novel genetic risk factor for flupirtine-induced liver injury.
Pharmacogenet Genomics
; 26(5): 218-24, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26959717
4.
Nomenclature for alleles of the thiopurine methyltransferase gene.
Pharmacogenet Genomics
; 23(4): 242-8, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23407052
5.
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers.
Biochem J
; 436(3): 671-9, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21434873
6.
Thiopurine methyltransferase genetics is not a major risk factor for secondary malignant neoplasms after treatment of childhood acute lymphoblastic leukemia on Berlin-Frankfurt-Münster protocols.
Blood
; 114(7): 1314-8, 2009 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19535798
7.
Increased DNA-incorporated thiopurine metabolite as a possible mechanism for leukocytopenia through cell apoptosis in inflammatory bowel disease patients with NUDT15 mutation.
J Gastroenterol
; 56(11): 999-1007, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34480209
8.
Metabolites of endophytic fungi from Australian native plants as potential anticancer agents.
FEMS Microbiol Lett
; 365(9)2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590360
9.
Azathioprine with Allopurinol: Lower Deoxythioguanosine in DNA and Transcriptome Changes Indicate Mechanistic Differences to Azathioprine Alone.
Inflamm Bowel Dis
; 23(6): 946-955, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28452864
10.
Liquid chromatography-mass spectrometry for measuring deoxythioguanosine in DNA from thiopurine-treated patients.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1028: 175-180, 2016 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27362994
11.
Molecular diagnostics: a healthcare perspective.
Expert Rev Mol Diagn
; 3(1): 13-6, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12528360
12.
Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers.
Mol Cancer Ther
; 10(3): 495-504, 2011 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-21282358
13.
Thiopurines: factors influencing toxicity and response.
Biochem Pharmacol
; 79(9): 1211-20, 2010 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20096268
14.
Chemotherapy individualization.
Invest New Drugs
; 21(2): 149-56, 2003 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12889736
15.
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs.
Mol Pharmacol
; 62(1): 102-9, 2002 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12065760