Detalhe da pesquisa
1.
Relative Performance of Volume of Distribution Prediction Methods for Lipophilic Drugs with Uncertainty in LogP Value.
Pharm Res
; 2024 May 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38720034
2.
Integrating Forward and Reverse Translation in PBPK Modeling to Predict Food Effect on Oral Absorption of Weakly Basic Drugs.
Pharm Res
; 40(2): 405-418, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36788156
3.
Exploring in vitro solubility of lamotrigine in physiologically mimetic conditions to prospect the in vivo dissolution in pediatric population.
Biopharm Drug Dispos
; 44(2): 147-156, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-36951570
4.
Pharmacokinetics of Benznidazole in Experimental Chronic Chagas Disease Using the Swiss Mouse-Berenice-78 Trypanosoma cruzi Strain Model.
Antimicrob Agents Chemother
; 65(2)2021 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33168611
5.
Scientific considerations to move towards biowaiver for biopharmaceutical classification system class III drugs: How modeling and simulation can help.
Biopharm Drug Dispos
; 42(4): 118-127, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33759204
6.
Assessing the impact of cystic fibrosis on the antipyretic response of ibuprofen in children: Physiologically-based modeling as a candle in the dark.
Br J Clin Pharmacol
; 86(11): 2247-2255, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32335930
7.
Linking in vitro-in vivo extrapolations with physiologically based modeling to inform drug and formulation development.
Biopharm Drug Dispos
; 44(4): 289-291, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37622923
8.
Integrating biopharmaceutics risk assessment and in vivo absorption model in formulation development of BCS class I drug using the QbD approach.
Drug Dev Ind Pharm
; 43(4): 668-677, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28032517
9.
Comparative Study of Basement-membrane Matrices for Human Stem Cell Maintenance and Intestinal Organoid Generation.
J Vis Exp
; (205)2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557663
10.
In Vitro Lipolysis Model to Predict Food Effect of Poorly Water-Soluble Drugs Itraconazole, Rivaroxaban, and Ritonavir.
J Pharm Sci
; 2024 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38614321
11.
Mechanistic Modeling of In Vitro Biopharmaceutic Data for a Weak Acid Drug: A Pathway Towards Deriving Fundamental Parameters for Physiologically Based Biopharmaceutic Modeling.
AAPS J
; 26(3): 44, 2024 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38575716
12.
Exploring the impact of CYP2D6 and UGT2B7 gene-drug interactions, and CYP-mediated DDI on oxycodone and oxymorphone pharmacokinetics using physiologically-based pharmacokinetic modeling and simulation.
Eur J Pharm Sci
; 194: 106689, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38171419
13.
Adult and pediatric physiologically-based biopharmaceutics modeling to explain lamotrigine immediate release absorption process.
CPT Pharmacometrics Syst Pharmacol
; 13(2): 208-221, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37916262
14.
Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Isavuconazonium Sulfate.
J Pharm Sci
; 113(2): 386-395, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37951471
15.
Real-world effect of a potential drug-drug interaction between topiramate and oral contraceptives on unintended pregnancy outcomes.
Contraception
; 120: 109953, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36641095
16.
A robust, viable, and resource sparing HPLC-based logP method applied to common drugs.
Int J Pharm
; 644: 123325, 2023 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37591472
17.
Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions.
Pharmaceutics
; 15(2)2023 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36839950
18.
Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure.
Pharmaceutics
; 15(5)2023 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37242635
19.
Comprehensive Physiologically Based Pharmacokinetic Model to Assess Drug-Drug Interactions of Phenytoin.
Pharmaceutics
; 15(10)2023 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37896246
20.
Effect of Roux-En-Y Gastric Bypass in the Pharmacokinetics of (R)-Carvedilol and (S)-Carvedilol.
J Clin Pharmacol
; 63(7): 838-847, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36854819