Potential for positive biodiversity outcomes under diet-driven land use change in Great Britain.

Background: A shift toward human diets that include more fruit and vegetables, and less meat is a potential pathway to improve public health and reduce food system-related greenhouse gas emissions. Associated changes in land use could include conversion of grazing land into horticulture, which makes more efficient use of land per unit of dietary energy and frees-up land for other uses. Methods: Here we use Great Britain as a case study to estimate potential impacts on biodiversity from converting grazing land to a mixture of horticulture and natural land covers by fitting species distribution models for over 800 species, including pollinating insects and species of conservation priority. Results: Across several land use scenarios that consider the current ratio of domestic fruit and vegetable production to imports, our statistical models suggest a potential for gains to biodiversity, including a tendency for more species to gain habitable area than to lose habitable area. Moreover, the models suggest that climate change impacts on biodiversity could be mitigated to a degree by land use changes associated with dietary shifts. Conclusions: Our analysis demonstrates that options exist for changing agricultural land uses in a way that can generate win-win-win outcomes for biodiversity, adaptation to climate change and public health.

Omega 3 fatty acid for the prevention of cognitive decline and dementia

BACKGROUND: Evidence from observational studies suggests that diets high in omega-3 long-chain polyunsaturated fatty acids (PUFA) may protect people from cognitive decline and dementia. The strength of this potential protective effect has recently been tested in randomized controlled trials. OBJECTIVES: To assess the effects of omega-3 PUFA supplementation for the prevention of dementia and cognitive decline in cognitively healthy older people. METHODS: Search: We searched ALOIS - the Cochrane Dementia and Cognitive Improvement Group's Specialized Register on - 6 April 2012 using the terms: "omega 3", PUFA, "fatty acids", "fatty acid", fish, linseed, eicosapentaenoic, docosahexaenoic. Selection criteria: Randomised controlled trials of an omega-3 PUFA intervention which was provided for a minimum of six months to participants aged 60 years and over who were free from dementia or cognitive impairment at the beginning of the study. Two review authors independently assessed all trials. Data collection and analysis: The review authors sought and extracted data on incident dementia, cognitive function, safety and adherence, either from published reports or by contacting the investigators for original data. Data were extracted by two review authors. We calculated mean difference (MD) or standardised mean differences (SMD) and 95% confidence intervals (CI) on an intention-to-treat basis, and summarized narratively information on safety and adherence. MAIN RESULTS: Information on cognitive function at the start of a study was available on 4080 participants randomised in three trials. Cognitive function data were available on 3536 participants at final follow-up. In two studies participants received gel capsules containing either omega-3 PUFA (the intervention) or olive or sunflower oil (placebo) for six or 24 months. In one study, participants received margarine spread for 40 months; the margarine for the intervention group contained omega-3 PUFA. Two studies had cognitive health as their primary outcome; one study of cardiovascular disease included cognitive health as an additional outcome. None of the studies examined the effect of omega-3 PUFA on incident dementia. In two studies involving 3221 participants there was no difference between the omega-3 and placebo group in mini-mental state examination score at final follow-up (following 24 or 40 months of intervention); MD-0.07 (95% CI -0.25 to 0.10). In two studies involving 1043 participants, other tests of cognitive function such as word learning, digit span and verbal fluency showed no beneficial effect of omega-3 PUFA supplementation. Participants in both the intervention and control groups experienced either small or no cognitive declines during the studies. The main reported side-effect of omega-3 PUFA supplementation was mild gastrointestinal problems. Overall, minor adverse events were reported by fewer than 15% of participants, and reports were balanced between intervention groups. Adherence to the intervention was on average over 90% among people who completed the trials. All three studies included in this review are of high methodological quality. AUTHORS' CONCLUSIONS: Direct evidence on the effect of omega-3 PUFA on incident dementia is lacking. The available trials showed no benefit of omega-3 PUFA supplementation on cognitive function in cognitively healthy older people. Omega-3 PUFA supplementation is generally well tolerated with the most commonly reported side-effect being mild gastrointestinal problems. Further studies of longer duration are required. Longer-term studies may identify greater change in cognitive function in study participants which may enhance the ability to detect the possible effects of omega-3 PUFA supplementation in preventing cognitive decline in older people.

Cumplimiento de la guía clínica de manejo ambulatorio de la neumonía adquirida en la comunidad en personas mayores en centros de atención primaria de salud de Santiago / Compliance with guidelines for the management of community acquired pneumonia at primary health care centers

Background: Community acquired pneumonia (CAP) has a high mortality rate among older people. To increase its treatment efficiency, the Chilean Ministry of Health elaborated a clinical management guideline for CAP. Aim: To assess the degree of compliance with the clinical guidelines for CAP among professionals working at primary health care centers. Material and methods: A follow up of a cohort of 2,797 subjects aged 67 years or more, incorporated to a clinical study. All cases of bronchopneumonia or pneumonia diagnosed at primary health care centers between September 2005 and June 2008 were recorded. Results: During the follow up period, 192 cases of CAP were diagnosed. A chest X-ray was requested in 81 percent of cases and a confirmation consultation was done in 58 percent. Amoxicillin/ Clavulanic acid was the most common antimicrobial prescription in 61 percent of cases, followed by Clarithromycin in 17 percent and Amoxicillin in 12 percent. The antimicrobial used was not registered in 5 percent of cases. Conclusions: The clinical guidelines improve the efficiency of CAP treatment and decrease complications. However, these guidelines must been complemented with an adequate training and supervision of health care teams.

Factores asociados a satisfacción vital en una cohorte de adultos mayores de Santiago, Chile / Factors associated with life satisfaction in a cohort of older people in Santiago, Chile

Objetivo Evaluar la asociación entre satisfacción vital con el nivel socioeconómico y el autorreporte del estado de salud en una cohorte de adultos mayores de Santiago de Chile en los años 2005 y 2006.MétodosEstudio transversal que incluyó 2002 sujetos entre 65 y 67,9 años de edad, registrados en 20 centros de salud primaria del Gran Santiago, autovalentes, sin deterioro cognitivo, sospecha de cáncer ni enfermedad terminal. Se evaluó la satisfacción vital mediante la adaptación abreviada de una escala de satisfacción con la vida (de 0 a 11), además de los ingresos económicos, el nivel de educación, el apoyo social y autorreporte del estado de salud y la memoria. Se utilizó un modelo log-binomial para analizar la asociación entre las variables evaluadas y los extremos del puntaje de satisfacción vital (cuartil 4 frente a 1). Resultados Se observó una asociación significativa (análisis bivariado y multivariado) entre satisfacción vital e ingresos económicos en los hombres, y en ambos sexos con el apoyo social, el autorreporte de salud, la memoria y los diagnósticos de problemas articulares, diabetes e hipertensión. Conclusión La situación económica, el apoyo social y el estado de salud se asocian de forma independiente con la satisfacción vital en los adultos mayores de Santiago. Se requieren nuevos estudios para evaluar la dirección temporal del efecto, así como las implicaciones de estos hallazgos en las políticas públicas de salud en esta población (AU)

Objective To evaluate the association between life satisfaction and socioeconomic status and self-reported health in a cohort of older people in Santiago, Chile, in 2005 and 2006.MethodsWe interviewed 2002 individuals aged 65 to 67.9 years registered in 20 primary care centers in the city of Santiago. Participants were living independently with no cognitive impairment, suspected cancer or terminal diseases. We assessed life satisfaction using an abbreviated adaptation of a life satisfaction scale (scored from 0 to 11), and collected self-reported information on income, education, social support, and self-reported health and memory. We used a log-binomial model to analyze the association between life satisfaction scores (fourth quartile compared with the first) and socioeconomic and health variables. Results There was a significant association (bivariate and multivariate analyses) between life satisfaction and income in men and with social support, self-reported health, memory, and diagnosis of joint problems, diabetes and hypertension in both sexes. Conclusion Social support, income and health status were independently associated with life satisfaction in older people aged 65-67.9 years in Santiago. Further studies are required to assess the temporal direction of the effect and the implications of these findings for public health policies in this population (AU)