Structural modification of titanium surface by octacalcium phosphate via Pulsed Laser Deposition and chemical treatment.

In the present study, the Pulsed Laser Deposition (PLD) technique was applied to coat titanium for orthopaedic and dental implant applications. Calcium carbonate (CC) was used as starting coating material. The deposited CC films were transformed into octacalcium phosphate (OCP) by chemical treatments. The results of X-ray diffraction (XRD), Raman, Fourier Transform Infrared Spectroscopy (FTIR) and scanning electron microscopy (SEM) studies revealed that the final OCP thin films are formed on the titanium surface. Human myofibroblasts from peripheral vessels and the primary bone marrow mesenchymal stromal cells (BMMSs) were cultured on the investigated materials. It was shown that all the investigated samples had no short-term toxic effects on cells. The rate of division of myofibroblast cells growing on the surface and saturated BMMSs concentration for the OCP coating were about two times faster than of cells growing on the CC films.

Glass-ceramic coated Mg-Ca alloys for biomedical implant applications.

Biodegradable metals and alloys are promising candidates for biomedical bone implant applications. However, due to the high rate of their biodegradation in human body environment, they should be coated with less reactive materials, such, for example, as bioactive glasses or glass-ceramics. Fort this scope, RKKP composition glass-ceramic coatings have been deposited on Mg-Ca(1.4wt%) alloy substrates by Pulsed Laser Deposition method, and their properties have been characterized by a number of techniques. The prepared coatings consist of hydroxyapatite and wollastonite phases, having composition close to that of the bulk target material used for depositions. The 100µm thick films are characterized by dense, compact and rough morphology. They are composed of a glassy matrix with various size (from micro- to nano-) granular inclusions. The average surface roughness is about 295±30nm due to the contribution of micrometric aggregates, while the roughness of the fine-texture particulates is approximately 47±4nm. The results of the electrochemical corrosion evaluation tests evidence that the RKKP coating improves the corrosion resistance of the Mg-Ca (1.4wt%) alloy in Simulated Body Fluid.

Haemostatic treatment of a bleeding hepatocarcinoma by polypropylene mesh wrapping in a cirrhotic patient.

Spontaneous rupture of hepatocarcinoma (HCC) in a cirrhotic patient is a serious complication with a high incidence of mortality. The pathogenesis of this complication is unknown. Several hypotheses have been proposed in the literature worldwide. The diagnosis, in the absence of specific symptoms, is made by ultrasound, sometimes followed by a CT scan, and finally by exploratory paracentesis. An angiogram is performed to locate the site of the bleeding and possibly allow transcatheter arterial chemo-embolisation. Therapeutic options include one-stage or delayed resection, packing for sub-diaphragmatic bleeding HCC's, and hepatic artery ligation. Suture ligation of the bleeding source is usually impossible due to the friability of the tumor. No sizeable experience with the use of alcoholisation for haemostasis has been reported to date. We report a case of HCC bleeding from segment VI successfully treated by manual compression and placement of a polypropylene mesh (Biomesh P1, Cousin Biotech).

Actualización en prevención y manejo de las trombosis en catéteres venosos centrales / Actualization in prevention and management of central venous catheter thrombosis

Central venous catheters are essential to the modern-day management of many illnesses especially cancer and hematologic desorders. Catheter malfuncion due to catheter tip thrombosis and catheter central venous thrombosis are two common complications. These two complication can cause significant problems in patient management and can be a sourse of morbitiy and occasional mortality. This review focuses on the incidence, risk factors, natural history, diagnostic aproaches, prophilaxis and treatment of thrombotic complications of central venous catheters in cancer patients.

Linfoma primario de próstata: nuevo caso clínico / Primary lymphoma of the prostate gland: a mew clinic case

Presentamos un nuevo caso de Linfoma Primario de Próstata. Hasta la fecha, se han comunicado aproximadamente 100 casos en la literatura mundial. Nuestro caso, se trata de un paciente de 73 años, que consultó por prostatismo. La anatomía patológica, obtenida por punción-biopsia transrectal informó linfoma tipo B, asociado con HBP. Los estudios complementarios de extensión de la enfermedad fueron todos negativos.. El paciente fue tratado mediante RTU, por uropatía obstructiva infravesical, más 6 ciclos de quimioterapia (CHOP). que debió completarse con radioterapia (5.940 cGy) para obtener la remisión completa. A la fecha, y con un seguimiento de 30 meses, el paciente se encuentra asintomático y libre de enfermedad