Detalhe da pesquisa
1.
A lower X-gate in TASK channels traps inhibitors within the vestibule.
Nature
; 582(7812): 443-447, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32499642
2.
POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK-1 in heart.
EMBO Rep
; 23(12): e55208, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36254885
3.
Characterization of Kv1.2-mediated outward current in TRIP8b-deficient mice.
Biol Chem
; 404(4): 291-302, 2023 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36852869
4.
Sigma-1 receptor modulation fine-tunes KV1.5 channels and impacts pulmonary vascular function.
Pharmacol Res
; 189: 106684, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36740150
5.
Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants.
Int J Mol Sci
; 24(2)2023 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36674868
6.
Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats.
Int J Mol Sci
; 24(12)2023 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37372947
7.
Hyperinsulinemic Hypoglycemia Associated with a CaV1.2 Variant with Mixed Gain- and Loss-of-Function Effects.
Int J Mol Sci
; 23(15)2022 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35897673
8.
Whole Exome Sequencing Identifies a Heterozygous Variant in the Cav1.3 Gene CACNA1D Associated with Familial Sinus Node Dysfunction and Focal Idiopathic Epilepsy.
Int J Mol Sci
; 23(22)2022 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430690
9.
Molecular Pharmacology of K2P Potassium Channels.
Cell Physiol Biochem
; 55(S3): 87-107, 2021 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33667333
10.
Molecular Mechanism of Autosomal Recessive Long QT-Syndrome 1 without Deafness.
Int J Mol Sci
; 22(3)2021 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33498651
11.
5-(Indol-2-yl)pyrazolo[3,4-b]pyridines as a New Family of TASK-3 Channel Blockers: A Pharmacophore-Based Regioselective Synthesis.
Molecules
; 26(13)2021 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34202296
12.
POPDC2 a novel susceptibility gene for conduction disorders.
J Mol Cell Cardiol
; 145: 74-83, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32535041
13.
Disease-associated HCN4 V759I variant is not sufficient to impair cardiac pacemaking.
Pflugers Arch
; 472(12): 1733-1742, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33095298
14.
POPDC3 Gene Variants Associate with a New Form of Limb Girdle Muscular Dystrophy.
Ann Neurol
; 86(6): 832-843, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31610034
15.
Elucidating the Structural Basis of the Intracellular pH Sensing Mechanism of TASK-2 K2P Channels.
Int J Mol Sci
; 21(2)2020 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31947679
16.
New Cav1.2 Channelopathy with High-Functioning Autism, Affective Disorder, Severe Dental Enamel Defects, a Short QT Interval, and a Novel CACNA1C Loss-Of-Function Mutation.
Int J Mol Sci
; 21(22)2020 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33203140
17.
Identification of the A293 (AVE1231) Binding Site in the Cardiac Two-Pore-Domain Potassium Channel TASK-1: a Common Low Affinity Antiarrhythmic Drug Binding Site.
Cell Physiol Biochem
; 52(5): 1223-1235, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31001961
18.
The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function.
FASEB J
; 32(11): 6159-6173, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29879376
19.
A Mutation in the G-Protein Gene GNB2 Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction.
Circ Res
; 120(10): e33-e44, 2017 May 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219978
20.
Calcium-activated SK potassium channels are key modulators of the pacemaker frequency in locus coeruleus neurons.
Mol Cell Neurosci
; 88: 330-341, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29524627