Detalhe da pesquisa
1.
Pharmacokinetics and pharmacodynamics of single and multiple doses of the glucagon receptor antagonist LGD-6972 in healthy subjects and subjects with type 2 diabetes mellitus.
Diabetes Obes Metab
; 19(1): 24-32, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27501510
2.
Single- and multiple-dose administration of caspofungin in patients with hepatic insufficiency: implications for safety and dosing recommendations.
J Clin Pharmacol
; 47(8): 951-61, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17660480
3.
Intravenous conivaptan: effects on the QTc interval and other electrocardiographic parameters in healthy volunteers.
Adv Ther
; 24(2): 310-8, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17565921
4.
Pharmacokinetics and pharmacodynamic effects of the oral DPP-4 inhibitor sitagliptin in middle-aged obese subjects.
J Clin Pharmacol
; 46(8): 876-86, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16855072
5.
Pharmacokinetics of long-acting naltrexone in subjects with mild to moderate hepatic impairment.
J Clin Pharmacol
; 45(11): 1259-67, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16239359
6.
Pharmacokinetics and safety of ebastine in patients with impaired hepatic function compared with healthy volunteers: a phase I open-label study.
Clin Pharmacokinet
; 43(2): 121-9, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14748620
7.
Pharmacokinetics of etoricoxib in patients with hepatic impairment.
J Clin Pharmacol
; 43(10): 1136-48, 2003 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14517196
8.
Evaluation of the single-dose pharmacokinetics of bilastine in subjects with various degrees of renal insufficiency.
Clin Drug Investig
; 33(9): 665-73, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23873362
9.
Effect of moderate hepatic insufficiency on the pharmacokinetics of sitagliptin.
Can J Clin Pharmacol
; 16(1): e165-70, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19221403
10.
Absolute bioavailability of sitagliptin, an oral dipeptidyl peptidase-4 inhibitor, in healthy volunteers.
Biopharm Drug Dispos
; 28(6): 315-22, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17575559
11.
Dose-proportionality of a final market image sitagliptin formulation, an oral dipeptidyl peptidase-4 inhibitor, in healthy volunteers.
Biopharm Drug Dispos
; 28(6): 307-13, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17571284
12.
Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C]sitagliptin in humans.
Drug Metab Dispos
; 35(4): 533-8, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17220239
13.
Potential for interactions between caspofungin and nelfinavir or rifampin.
Antimicrob Agents Chemother
; 48(11): 4306-14, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15504857
14.
Disposition of caspofungin: role of distribution in determining pharmacokinetics in plasma.
Antimicrob Agents Chemother
; 48(3): 815-23, 2004 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-14982770