Detalhe da pesquisa
1.
Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors.
Pharmacol Rev
; 67(4): 1025-73, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26419447
2.
Longitudinal Changes in Measured Glomerular Filtration Rate, Renal Fibrosis and Biomarkers in a Rat Model of Type 2 Diabetic Nephropathy.
Am J Nephrol
; 44(5): 339-353, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27736813
3.
GDF15 is a dynamic biomarker of the integrated stress response in the central nervous system.
CNS Neurosci Ther
; 30(2): e14600, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38357857
4.
Synthesis and SAR of 4-aminocyclopentapyrrolidines as N-type Ca²âº channel blockers with analgesic activity.
Bioorg Med Chem
; 20(13): 4128-39, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22626552
5.
Comparative analysis of inactivated-state block of N-type (Ca(v)2.2) calcium channels.
Inflamm Res
; 60(7): 683-93, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21394563
6.
Synthesis and in vitro activity of N-benzyl-1-(2,3-dichlorophenyl)-1H-tetrazol-5-amine P2X(7) antagonists.
Bioorg Med Chem Lett
; 21(11): 3297-300, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21536435
7.
NRF2 activator A-1396076 ameliorates inflammation in autoimmune disease models by inhibiting antigen dependent T cell activation.
J Transl Autoimmun
; 4: 100079, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33490940
8.
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
J Med Chem
; 64(1): 417-429, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33378180
9.
Small Molecule Phenotypic Screen Identifies Novel Regulators of LDLR Expression.
ACS Chem Biol
; 15(12): 3262-3274, 2020 12 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33270420
10.
[3H]A-804598 ([3H]2-cyano-1-[(1S)-1-phenylethyl]-3-quinolin-5-ylguanidine) is a novel, potent, and selective antagonist radioligand for P2X7 receptors.
Neuropharmacology
; 56(1): 223-9, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18602931
11.
Characterization of psoriasiform dermatitis induced by systemic injection of interleukin-23 minicircles in mice.
J Dermatol
; 46(6): 482-497, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31062408
12.
Small Molecule and Pooled CRISPR Screens Investigating IL17 Signaling Identify BRD2 as a Novel Contributor to Keratinocyte Inflammatory Responses.
ACS Chem Biol
; 14(5): 857-872, 2019 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30938974
13.
eIF2B activator prevents neurological defects caused by a chronic integrated stress response.
Elife
; 82019 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30624206
14.
Painful purinergic receptors.
J Pharmacol Exp Ther
; 324(2): 409-15, 2008 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-18042830
15.
Structure-activity relationship studies on N'-aryl carbohydrazide P2X7 antagonists.
J Med Chem
; 51(10): 3030-4, 2008 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18438986
16.
Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists.
Bioorg Med Chem Lett
; 18(6): 2089-92, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18272366
17.
Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists.
Bioorg Med Chem Lett
; 18(6): 2093-6, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18272365
18.
Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists.
Bioorg Med Chem Lett
; 18(14): 3848-51, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18595695
19.
Losartan improves renal function and pathology in obese ZSF-1 rats.
J Basic Clin Physiol Pharmacol
; 29(3): 281-290, 2018 Jun 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397387
20.
Short-term oral gavage administration of adenine induces a model of fibrotic kidney disease in rats.
J Pharmacol Toxicol Methods
; 94(Pt 1): 34-43, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29684554