1.
Bioorg Med Chem Lett
; 19(6): 1830-4, 2009 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19237282
RESUMO
A series of novel 1-aminocyclopentyl-3-carboxyamides incorporating substituted tetrahydropyran moieties have been synthesized and subsequently evaluated for their antagonistic activity against the human CCR2 receptor. Among them analog 59 was found to posses potent antagonistic activity.