Detalhe da pesquisa
1.
T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization.
Arthritis Rheum
; 64(6): 1762-70, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22213107
2.
Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.
Bioorg Med Chem Lett
; 21(12): 3823-7, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21565498
3.
Therapeutic antibody targeting of CD97 in experimental arthritis: the role of antigen expression, shedding, and internalization on the pharmacokinetics of anti-CD97 monoclonal antibody 1B2.
J Immunol
; 183(6): 4127-34, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19717518
4.
Biophysical and Immunological Characterization and In Vivo Pharmacokinetics and Toxicology in Nonhuman Primates of the Anti-PD-1 Antibody Pembrolizumab.
Mol Cancer Ther
; 19(6): 1298-1307, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229606
5.
APRIL signaling via TACI mediates immunosuppression by T regulatory cells in multiple myeloma: therapeutic implications.
Leukemia
; 33(2): 426-438, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30135465
6.
Corrigendum: Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.
Front Immunol
; 9: 2471, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30393473
7.
Bacillus Calmette-Guérin-Induced Trained Immunity Is Not Protective for Experimental Influenza A/Anhui/1/2013 (H7N9) Infection in Mice.
Front Immunol
; 9: 869, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29760700
8.
DHEA metabolism in arthritis: a role for the p450 enzyme Cyp7b at the immune-endocrine crossroad.
Ann N Y Acad Sci
; 1069: 401-13, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16855167
9.
Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis.
PLoS One
; 7(6): e38889, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22719976
10.
PD-1 blockade augments Th1 and Th17 and suppresses Th2 responses in peripheral blood from patients with prostate and advanced melanoma cancer.
J Immunother
; 35(2): 169-78, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22306905
11.
Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta.
Arthritis Res Ther
; 12(3): R101, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20497523
12.
Tumour necrosis factor-alpha stimulates dehydroepiandrosterone metabolism in human fibroblast-like synoviocytes: a role for nuclear factor-kappaB and activator protein-1 in the regulation of expression of cytochrome p450 enzyme 7b.
Arthritis Res Ther
; 7(6): R1271-80, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16277680
13.
CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
Arthritis Rheum
; 52(3): 770-8, 2005 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-15751070
14.
A study on cell lineage, especially the germ cell line, in embryos of the teleost fish,Barbus conchonius.
Rouxs Arch Dev Biol
; 201(5): 275-283, 1992 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28305831
15.
Severity of murine collagen-induced arthritis correlates with increased CYP7B activity: enhancement of dehydroepiandrosterone metabolism by interleukin-1beta.
Arthritis Rheum
; 50(10): 3346-53, 2004 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-15476247