Detalhe da pesquisa
1.
The structural and biochemical foundations of thiamin biosynthesis.
Annu Rev Biochem
; 78: 569-603, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19348578
2.
Structural Basis of the Substrate Selectivity of Viperin.
Biochemistry
; 59(5): 652-662, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31917549
3.
Co-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesis.
Nature
; 510(7505): 427-31, 2014 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24814342
4.
Structural studies of viperin, an antiviral radical SAM enzyme.
Proc Natl Acad Sci U S A
; 114(26): 6806-6811, 2017 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607080
5.
The Crystal Structure of Dph2 in Complex with Elongation Factor 2 Reveals the Structural Basis for the First Step of Diphthamide Biosynthesis.
Biochemistry
; 58(43): 4343-4351, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31566354
6.
Menaquinone Biosynthesis: Biochemical and Structural Studies of Chorismate Dehydratase.
Biochemistry
; 58(14): 1837-1840, 2019 04 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30855131
7.
Lysine relay mechanism coordinates intermediate transfer in vitamin B6 biosynthesis.
Nat Chem Biol
; 13(3): 290-294, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28092359
8.
Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase.
Biochemistry
; 56(30): 3934-3944, 2017 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28665591
9.
Substrate-Dependent Cleavage Site Selection by Unconventional Radical S-Adenosylmethionine Enzymes in Diphthamide Biosynthesis.
J Am Chem Soc
; 139(16): 5680-5683, 2017 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28383907
10.
Saccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthase.
Nature
; 478(7370): 542-6, 2011 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22031445
11.
Crystal Structures of the Iron-Sulfur Cluster-Dependent Quinolinate Synthase in Complex with Dihydroxyacetone Phosphate, Iminoaspartate Analogues, and Quinolinate.
Biochemistry
; 55(30): 4135-9, 2016 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404889
12.
Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Biochemistry
; 55(19): 2748-59, 2016 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27070241
13.
Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.
Biochemistry
; 55(12): 1826-38, 2016 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26919468
14.
Polyketide Ring Expansion Mediated by a Thioesterase, Chain Elongation and Cyclization Domain, in Azinomycin Biosynthesis: Characterization of AziB and AziG.
Biochemistry
; 55(4): 704-14, 2016 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26731610
15.
Radical S-adenosylmethionine (SAM) enzymes in cofactor biosynthesis: a treasure trove of complex organic radical rearrangement reactions.
J Biol Chem
; 290(7): 3980-6, 2015 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25477515
16.
From Suicide Enzyme to Catalyst: The Iron-Dependent Sulfide Transfer in Methanococcus jannaschii Thiamin Thiazole Biosynthesis.
J Am Chem Soc
; 138(11): 3639-42, 2016 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26928142
17.
Different polyamine pathways from bacteria have replaced eukaryotic spermidine biosynthesis in ciliates Tetrahymena thermophila and Paramecium tetaurelia.
Mol Microbiol
; 97(5): 791-807, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25994085
18.
Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme.
Nature
; 465(7300): 891-6, 2010 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20559380
19.
Anaerobic 5-Hydroxybenzimidazole Formation from Aminoimidazole Ribotide: An Unanticipated Intersection of Thiamin and Vitamin B12 Biosynthesis.
J Am Chem Soc
; 137(33): 10444-7, 2015 Aug 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26237670
20.
Structural and mechanistic studies of HpxO, a novel flavin adenine dinucleotide-dependent urate oxidase from Klebsiella pneumoniae.
Biochemistry
; 52(3): 477-87, 2013 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23259842