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1.
Cleft Palate Craniofac J ; 60(10): 1189-1198, 2023 10.
Artigo em Inglês | MEDLINE | ID: mdl-35532040

RESUMO

OBJECTIVE: Describe the first hybrid global simulation-based comprehensive cleft care workshop, evaluate impact on participants, and compare experiences based on in-person versus virtual attendance. DESIGN: Cross-sectional survey-based evaluation. SETTING: International comprehensive cleft care workshop. PARTICIPANTS: Total of 489 participants. INTERVENTIONS: Three-day simulation-based hybrid comprehensive cleft care workshop. MAIN OUTCOME MEASURES: Participant demographic data, perceived barriers and interventions needed for global comprehensive cleft care delivery, participant workshop satisfaction, and perceived short-term impact on practice stratified by in-person versus virtual attendance. RESULTS: The workshop included 489 participants from 5 continents. The response rate was 39.9%. Participants perceived financial factors (30.3%) the most significant barrier and improvement in training (39.8%) as the most important intervention to overcome barriers facing cleft care delivery in low to middle-income countries. All participants reported a high level of satisfaction with the workshop and a strong positive perceived short-term impact on their practice. Importantly, while this was true for both in-person and virtual attendees, in-person attendees reported a significantly higher satisfaction with the workshop (28.63 ± 3.08 vs 27.63 ± 3.93; P = .04) and perceived impact on their clinical practice (22.37 ± 3.42 vs 21.02 ± 3.45 P = .01). CONCLUSION: Hybrid simulation-based educational comprehensive cleft care workshops are overall well received by participants and have a positive perceived impact on their clinical practices. In-person attendance is associated with significantly higher satisfaction and perceived impact on practice. Considering that financial and health constraints may limit live meeting attendance, future efforts will focus on making in-person and virtual attendance more comparable.


Assuntos
Fenda Labial , Fissura Palatina , Humanos , Fissura Palatina/terapia , Fenda Labial/terapia , Estudos Transversais , Cabeça , Satisfação Pessoal
2.
Med Sci Monit ; 26: e921401, 2020 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-32588836

RESUMO

BACKGROUND The purpose of this prospective study was to compare adolescent and post-adolescent growth periods regarding the effectiveness of conventional activator appliance in patients with Class II mandibular retrognathia by using lateral cephalometric radiographs and three-dimensional photogrammetry (3dMDface). MATERIAL AND METHODS We enrolled 2 groups: 15 patients in the adolescent growth period and 17 patients in the post-adolescent growth period. All patients had Class II anomaly with mandibular retrognathia and were treated with conventional activator appliances. Lateral cephalometric radiographs and three-dimensional photogrammetric views were obtained at the beginning and end of the activator treatment of Class II patients. Maxillomandibular discrepancy, mandibular protrusion and lengths, convexity angles, facial heights, and dental measurements were evaluated cephalometrically. Projections of the lips and the chin and volumetric measurements of the lip and the mandibular area were assessed using three-dimensional photogrammetry. RESULTS Conventional activator therapy resulted in similar effects in both growth periods regarding improvements in the mandibular sagittal growth and maxillomandibular relationship (ANB° and the SNB° angles). Mandibular effective length was increased (Co-Gn length) and the maxillary horizontal growth was restricted (decreased SNA° angle) in both groups following the treatment. Treatment duration was significantly longer in the post-adolescent group. Increases in the projections of menton, pogonion, and sublabial points were observed in the three-dimensional photogrammetric views. Total lip volume was reduced while the mandibular volume was significantly increased in both groups. Lower gonial angle showed a greater increase in the post-adolescent group. CONCLUSIONS Correction of Class II anomaly with mandibular retrognathia was achieved with a combination of dental and skeletal changes in both growth periods. Conventional activator therapy may be an alternative treatment approach in the late growth period as it led to significant skeletal and dental changes.


Assuntos
Aparelhos Ativadores , Má Oclusão Classe II de Angle/terapia , Mandíbula/diagnóstico por imagem , Retrognatismo/terapia , Adolescente , Fatores Etários , Desenvolvimento Ósseo , Ossos do Carpo/diagnóstico por imagem , Ossos do Carpo/crescimento & desenvolvimento , Cefalometria , Criança , Feminino , Ossos da Mão/diagnóstico por imagem , Ossos da Mão/crescimento & desenvolvimento , Humanos , Imageamento Tridimensional , Masculino , Má Oclusão Classe II de Angle/diagnóstico por imagem , Mandíbula/anormalidades , Maxila/diagnóstico por imagem , Desenvolvimento Maxilofacial , Fotogrametria , Estudos Prospectivos , Retrognatismo/diagnóstico por imagem , Resultado do Tratamento
3.
Cleft Palate Craniofac J ; 57(10): 1238-1246, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32729337

RESUMO

OBJECTIVE: Evaluate simulation-based comprehensive cleft care workshops as a reproducible model for education with sustained impact. DESIGN: Cross-sectional survey-based evaluation. SETTING: Simulation-based comprehensive cleft care workshop. PARTICIPANTS: Total of 180 participants. INTERVENTIONS: Three-day simulation-based comprehensive cleft care workshop. MAIN OUTCOME MEASURES: Number of workshop participants stratified by specialty, satisfaction with the workshop, satisfaction with simulation-based workshops as educational tools, impact on cleft surgery procedural confidence, short-term impact on clinical practice, medium-term impact on clinical practice. RESULTS: The workshop included 180 participants from 5 continents. The response rate was 54.5%, with participants reporting high satisfaction with all aspects of the workshop and with simulation-based workshops as educational tools. Participants reported a significant improvement in cleft lip (33.3 ± 5.7 vs 25.7 ± 7.6; P < .001) and palate (32.4 ± 7.1 vs 23.7 ± 6.6; P < .001) surgery procedural confidence following the simulation sessions. Participants also reported a positive short-term and medium-term impact on their clinical practices. CONCLUSION: Simulation-based comprehensive cleft care workshops are well received by participants, lead to improved cleft surgery procedural confidence, and have a sustained positive impact on participants' clinical practices. Future efforts should focus on evaluating and quantifying this perceived positive impact, as well reproducing these efforts in other areas of need.


Assuntos
Fenda Labial , Fissura Palatina , Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Simulação por Computador , Estudos Transversais , Humanos
4.
Cleft Palate Craniofac J ; 57(4): 529-531, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-31960709

RESUMO

Many orthodontists working on patients with cleft lip and palate (CLP) have shown great enthusiasm for presurgical infant orthopedics (PSIO) to improve surgical outcomes with minimal intervention. Even though every clinician aims to use the best treatment modality for their patients, PSIO effects can be confounded by surgical type and timing of the primary repair, as is discussed in many studies. In such cases, one should be cautious when evaluating the particular outcomes for patients with CLP since it is difficult to differentiate the sole effect of an individual surgical or orthodontic intervention. As with any treatment methodology, nasoalveolar molding (NAM) has both benefits and limitations. Commonly cited concerns with NAM, and PSIO in general, include increased cost, increased burden of care, and a negative impact on maxillary growth. However, NAM cannot be deemed as having apparent long-term negative or positive effects on skeletal or soft tissue facial growth, based on previous studies. A review of the literature suggests that NAM does not alter skeletal facial growth when compared with the samples that did not receive PSIO. Nevertheless, the published studies on NAM show evidence of benefits to the patient, caregivers, the surgeon, and society. These benefits include documented reduction in severity of the cleft deformity prior to surgery and as a consequence improved surgical outcomes, reduced burden of care on the care givers, reduction in the need for revision surgery, and consequent reduced overall cost of care to the patient and society.


Assuntos
Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Procedimentos Ortopédicos , Procedimentos de Cirurgia Plástica , Humanos , Lactente , Maxila , Nariz/cirurgia
5.
J Craniofac Surg ; 30(8): 2565-2569, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31689732

RESUMO

This clinical report presents the outcomes of segmental corticotomy-assisted orthodontic treatment in a class III patient. A 13.5-year-old female patient presented with class III anomaly and a thin alveolus in the mandibular anterior region. After the alignment of the mandibular incisors, segmental corticotomy with platelet-rich fibrin (PRF) was performed in the mandibular incisor area to facilitate incisor retraction to ensure periodontal support after the changes in the inclination of the teeth. Lateral cephalograms were taken at the beginning (T0), precorticotomy (T1), at the end of the treatment (T2), and 2 years after the treatment (T3). Cone-beam computed tomography (CBCT) records were collected at the T1, T2, and T3 periods to evaluate the bone structures. The measurements included the inclination and the position of the mandibular incisors, symphysis width, symphysis height, B-B' width, cervical alveolar width, the vertical alveolar bone level on the labial and the lingual sides, and the amount of labial and lingual bone at the apex in the mandibular central incisor and canine areas.The class I molar and canine relationship was achieved in this borderline case. The amount of labial bone at the root apex and the B-B' width increased. A vertical alveolar bone gain was observed. The facial profile was improved significantly. The treatment outcome was stable at the 2-year follow-up. The segmental anterior mandibular corticotomy provided an effective correcting inclination of the mandibular teeth with the use of class III elastics. This technique ensured the maintenance of a sufficient amount of labial bone with no periodontal side effects.


Assuntos
Má Oclusão Classe III de Angle/cirurgia , Fibrina Rica em Plaquetas , Adolescente , Tomografia Computadorizada de Feixe Cônico/métodos , Feminino , Humanos , Incisivo , Má Oclusão Classe III de Angle/diagnóstico por imagem , Mandíbula
6.
J Craniofac Surg ; 30(6): 1640-1643, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30950956

RESUMO

This retrospective cohort study aimed to determine the impact of a nasoalveolar molding (NAM) protocol on midface growth in school-aged children with non-syndromic unilateral cleft lip and palate (UCLP). Data from 56 consecutively treated, NAM-prepared, Caucasian patients with non-syndromic UCLP from a single US cleft palate center were compared to pooled center data based on 56 patients with non-syndromic UCLP treated at 2 Eurocleft centers that did not use presurgical infant orthopedics (non-PSIO). Lateral cephalograms were obtained and 28 landmarks were identified. Published cephalometric measurements from Eurocleft centers were used for comparison. Seven cephalometric measurements (SNA, SNB, ANB, A'N'B', G'-Sn'-Pg', Sn-CT-LS, ANS-Me/N-Me%), available or derivable for both centers, were analyzed. Means and standard deviations for the 7 measurements were calculated for the NAM center. Student's t-tests were used to compare group means for 6 of the measures and a test of proportion was used for ANS-Me/N-Me%. No significant differences were found between the NAM protocol-prepared group and the Eurocleft non-PSIO centers on any of the 7 analyzed cephalometric relationships after accounting for false discovery rate. The NAM treatment protocol does not appear to impact skeletal or soft tissue facial growth in school-aged children with non-syndromic UCLP.


Assuntos
Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Face/cirurgia , Cefalometria/métodos , Criança , Feminino , Humanos , Masculino , Desenvolvimento Maxilofacial , Procedimentos Ortopédicos , Estudos Retrospectivos
7.
Med Sci Monit ; 24: 8608-8620, 2018 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-30484438

RESUMO

BACKGROUND In cleft lip and palate (CLP) patients, the shape of the facial soft tissues shows variety in 3 dimensions (3D). Two-dimensional (2D) photographs and radiographs are insufficient in the examination of these anomalies. The aim of this retrospective study was to examine the soft tissue and craniofacial characteristics of individuals with nonsyndromic unilateral cleft lip and palate (UCLP), bilateral cleft lip and palate (BCLP), skeletal Class III malocclusions, or skeletal Class I malocclusions using 3D facial imaging. MATERIAL AND METHODS The entire study group consisted of a total of 158 patients, aged 8-32 years: 29 of the patients had UCLP, 22 BCLP, 54 had skeletal Class III malocclusions, and 53 had skeletal Class I malocclusions. 3D stereophotogrammetric soft-tissue recordings of all patients were analyzed. ANOVA and the Kruskal-Wallis test were performed to compare the groups. RESULTS Statistically significant differences were observed among the groups in terms of linear, angular, proportional. and volumetric measurements. While nasal differences were not observed in the Class III group, nose and upper-lip deformities were common in the CLP groups. Upper-lip projection was reduced in all 3 groups. In the Class III patients, the lower lip and chin were more prominent than in the other groups. The facial convexity angle was increased in the CLP and Class III groups. The upper-lip volume was decreased in the BCLP, the UCLP, and the Class III groups. CONCLUSIONS Patients with skeletal Class III or CLP anomalies showed significantly different soft-tissue characteristics than the Class I control group. 3D stereophotogrammetric facial imaging is an easy and noninvasive method that can be used in examination and recording of these facial deformities. It is possible to make volumetric measurements using this method.


Assuntos
Fenda Labial/diagnóstico por imagem , Fissura Palatina/diagnóstico por imagem , Imageamento Tridimensional/métodos , Adolescente , Osso e Ossos/diagnóstico por imagem , Criança , Fenda Labial/patologia , Fissura Palatina/patologia , Feminino , Humanos , Masculino , Palato/diagnóstico por imagem , Fotogrametria/métodos , Estudos Retrospectivos , Adulto Jovem
8.
J Craniofac Surg ; 27(3): e289-91, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27054420

RESUMO

Rehabilitation of the large alveolar clefts with autogenous graft or distraction osteogenesis is one of the most common treatment choices. Depending on the clinical situation such as vertical deficiencies, linear transport of the segment does not always ensure a proper closure of the cleft space. In this report, the authors present a patient in whom large unilateral cleft and vertical alveolar deficiency were closed by unilateral Le Fort I osteotomy and distraction technique using the orthodontic elastics.


Assuntos
Fenda Labial/cirurgia , Fissura Palatina/cirurgia , Má Oclusão/cirurgia , Maxila/cirurgia , Osteogênese por Distração/métodos , Osteotomia de Le Fort/métodos , Humanos , Masculino , Adulto Jovem
9.
Cleft Palate Craniofac J ; 53(4): 481-90, 2016 07.
Artigo em Inglês | MEDLINE | ID: mdl-26120884

RESUMO

OBJECTIVE: A male patient with Tessier No. 4 cleft (unilateral left) presented at 20 days of age. The cleft defect beginning between the cupid bow and oral commissure extended to the ipsilateral orbital floor, skirting the nose and lacrimal duct while passing through the cheek medial to the infraorbital nerve. With the lesser segment disposed 16 mm transversely, the wide gap included an absence of orbital floor and lower eyelid. A deficient midfacial platform caused a severe inferior globe dystopia, superiorly displaced left ala base, and severe vertical shortening between ala-canthus and ala-globe. INTERVENTION: A modified Latham device applied directional orthopedics to contract the cleft gap and with an eye part added to elevate the dystopic globe. Two different Latham devices used in succession were each applied for 4 weeks. Lastly, a removable plate further repositioned the eye. Each appliance was designed to differentially move the noncleft and cleft segments of the maxilla. Presurgical orthopedics began at 3 weeks lasted 14 weeks. Intraoperatively at 17 weeks, the inferior globe dystopia was effectively reduced, and the cleft gaps were nearly closed and aligned at the orbital floor, cheek, and the alveolus. Respecting the aesthetic units of face became possible with the soft-tissue repair yet were tight enough in the malar region to retract the lower lid. CONCLUSION: The presurgical directional orthopedic and eye-globe mechanics were sufficient to enable medial canthal repositioning, sustainable correction of orbital distopia, and optimized primary soft-tissue repair. Early result suggests that surgery with presurgical orthopedics is superior to surgery alone.


Assuntos
Fenda Labial/cirurgia , Face/cirurgia , Órbita/cirurgia , Ortopedia , Fissura Palatina , Humanos , Lactente , Masculino , Maxila
10.
Eur J Orthod ; 38(3): 313-23, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26219549

RESUMO

INTRODUCTION: The aim of this study was to compare the short-term dental and skeletal effects of a face mask (FM) with those of skeletal anchorage (SA) therapy with intermaxillary elastics in prepubertal patients with skeletal Class III malocclusion. METHODS: Fifty patients with skeletal Class III malocclusion and maxillary deficiency were divided into two groups. In the FM group, an FM was applied by a bite plate with a force of 400g for each side. In the SA group, mini-plates were placed between mandibular lateral incisors and canines, and mini-implants were inserted between maxillary second premolars and first molars. A bite plate was inserted into the upper arch, and Class III elastics were applied with a force of 200g between each mini-plate and mini-implant. RESULTS: Mean treatment durations were 0.52±0.09 years for FM and 0.76±0.09 years for SA. After the treatment, statistically significant increases in SNA°, ANB°, A-y, 1-NA, SnGoGn°, Co-A, Co-Gn, and A-Nperp, and reductions in SNB° and FH┴N-Pg were observed in both groups, and these changes were similar in both groups. In the FM group, 1-NB decreased significantly, and in the SA group, it increased significantly (P < 0.05). CONCLUSIONS: The undesired dentoalveolar effects of the FM treatment were eliminated with SA treatment, except with regard to lower incisor inclination. Favourable skeletal outcomes can be achieved by SA therapies, which could be an alternative to the extraoral appliances frequently applied to treat skeletal Class III patients with maxillary deficiency.


Assuntos
Aparelhos de Tração Extrabucal , Má Oclusão Classe III de Angle/terapia , Máscaras , Procedimentos de Ancoragem Ortodôntica/métodos , Retrognatismo/terapia , Adolescente , Cefalometria/métodos , Criança , Oclusão Dentária , Elastômeros , Feminino , Humanos , Incisivo , Masculino , Maxila/diagnóstico por imagem , Maxila/patologia , Dente Molar , Radiografia Dentária , Retrognatismo/diagnóstico por imagem , Retrognatismo/patologia
11.
Aust Orthod J ; 31(1): 2-13, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-26219141

RESUMO

INTRODUCTION: The aim of this study was to evaluate the dentoskeletal effects of a modified slow maxillary expansion appliance (MSMEA) during the transition from the mixed to the permanent dentition. METHODS: Forty subjects presenting with posterior crossbites were divided into two groups. Twenty-three subjects were assigned to a treatment group (mean age: 9.45 years) and 17 subjects assigned to a control group (mean age: 9.25 years). An MSMEA with acrylic occlusal coverage limited to the palatal cusps was used to provide maxillary expansion. The mean slow expansion treatment period was 7.8 months, while the mean observation period continued for 14.8 months of a 22.6-month total study period. RESULTS: Substantial dental and skeletal effects were observed following treatment with the MSMEA. Most maxillary inter-molar and deciduous inter-second molar width increases were maintained in the permanent dentition (91% and 97%, respectively). Skeletal maxillary transverse dimensions, which increased by 2 mm after active expansion, were significantly greater (p < 0.001) when compared with the controls. CONCLUSION: The findings suggested that an MSMEA provided orthopaedic and dental effects as a result of posterior crossbite correction. The effects of the appliance seen during the mixed dentition were maintained in the permanent dentition.


Assuntos
Dentição Mista , Técnica de Expansão Palatina , Dente Pré-Molar/patologia , Cefalometria/métodos , Criança , Dente Canino/patologia , Arco Dental/patologia , Seguimentos , Humanos , Má Oclusão/terapia , Mandíbula/patologia , Maxila/patologia , Dente Molar/patologia , Osso Nasal/patologia , Desenho de Aparelho Ortodôntico , Aparelhos Ortodônticos Removíveis , Técnica de Expansão Palatina/instrumentação , Fotografação/métodos , Sela Túrcica/patologia , Dente Decíduo/patologia , Resultado do Tratamento
12.
Am J Orthod Dentofacial Orthop ; 145(2): 217-27, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24485737

RESUMO

INTRODUCTION: We aimed to investigate the morphometric development of the cranial base and its related structures, and their growth rate changes from the ninth gestational week to full term in a large group of human fetuses. METHODS: We selected 203 (109 male, 94 female) fetuses between 9 and 40 weeks of gestation and without any external anomalies. From each fetus, standard lateral and posteroanterior cephalometric images were taken using a dental digital panoramic and cephalometric x-ray machine. Fourteen linear and 9 angular parameters were measured. RESULTS: The cranial base angle showed a statistically significant increase between the groups from only the second to the third trimester periods. The sagittal translation of the maxilla increased during the prenatal period, whereas the mandibular sagittal relation grew at a steady rate. The vertical plane angles of the maxilla and the mandible did not show any significant changes. The maxillary length to mandibular length ratio remained stable. CONCLUSIONS: The cranial base angle increased, especially in the second through the third trimesters. The maxilla and the mandible demonstrated different growth patterns in the sagittal direction. The findings of this study could be a guide for interpreting the relationships among the craniofacial structures.


Assuntos
Cefalometria/métodos , Ossos Faciais/embriologia , Desenvolvimento Fetal/fisiologia , Crânio/embriologia , Cadáver , Queixo/embriologia , Estatura Cabeça-Cóccix , Feminino , Fêmur/embriologia , Feto , Pé/embriologia , Idade Gestacional , Humanos , Masculino , Mandíbula/embriologia , Maxila/embriologia , Osso Nasal/embriologia , Organogênese/fisiologia , Osso Parietal/embriologia , Radiografia Dentária Digital/métodos , Radiografia Panorâmica/métodos , Sela Túrcica/embriologia , Base do Crânio/embriologia
13.
J Orofac Orthop ; 2024 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-38378857

RESUMO

PURPOSE: The aim of this respectively cohort study was to evaluate the lower second and third molars and canine angulations, retromolar space and occlusal relationships after functional orthodontic treatments with the monoblock or Herbst appliance using panoramic radiographs. METHODS: Pre- and posttreatment cephalometric and panoramic radiographs of 133 patients (mean age 13.89 ± 1.14 years) treated non-extraction with monoblock (n: 44), Herbst (n: 45) and fixed orthodontic appliances (control group; n: 44) were included to the study. Dental and skeletal measurements were performed on cephalometric radiographs. The angle between the third and second molars, and canines with the lower border of the mandible and the occlusal plane, gonial angle, the angle between the third and second molars and the retromolar space width were assessed on pre- and posttreatment panoramic radiographs. Paired and independent t tests were used for the statistical analysis of the data for intragroup and intergroup comparisons. RESULTS: Functional treatment with both the monoblock and the Herbst appliances resulted in improvement of skeletal class II relationships. Retromolar space significantly increased in the functional appliance groups compared to the control group (p ≤ 0.001), but improvement of the angulations of posterior teeth was significant only in the monoblock group (p ≤ 0.001). CONCLUSION: While both the Herbst and monoblock appliances led to an increase in retromolar space, monoblock treatment resulted in more favorable angulation of the third molars compared to the Herbst treatment.

14.
Cleft Palate Craniofac J ; 50(4): e61-73, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22849638

RESUMO

Objective : The aim of the present study was to compare the morphometrics of the craniofacial and alveolar arch structures of anencephalic fetuses with those of normal human fetuses without anencephaly or any other anomaly. Design : Original article. Methods : Standard lateral and posteroanterior cephalometric radiographs of 23 anencephalic and 33 normal human fetuses aged between 21 and 40 weeks of gestation were compared. These fetuses were divided into three periods based on gestational age, and vertical, sagittal, transverse, and angular measurements were taken in the cranial base and facial regions. Moreover, intraoral measurements from the maxillary and mandibular arches were also made to determine the width and depth. Results : N-S and S-Ba lengths and the N-S-Ba angle, measured on lateral cephalometric radiographs, were statistically smaller in anencephalic fetuses (p < .05). The S-N-ANS, S-N-Pg, and ANS-N-Pg angles and the Go-Me length were significantly greater in anencephalic fetuses (p < .05). Maxillary length, ramus length, and anterior facial heights were similar in both groups. On posteroanterior radiographs, all parameters except bigonial distance were found to be smaller in the anencephalic fetuses (p < .05). Maxillary alveolar width was small among anencephalic fetuses in all three periods; whereas, the mandibular alveolar width was narrow only in the third period. Conclusion : Cranial and facial structures were affected morphometrically to various degrees in anencephalic cases. The most significant alterations in anencephalic cases were related to measurements in the transverse direction. This indicated that cephalic tissue influenced not only the cranial base but also all facial structures.


Assuntos
Cefalometria , Feto , Anencefalia , Humanos , Mandíbula , Maxila
15.
Turk J Orthod ; 36(4): 231-238, 2023 Dec 29.
Artigo em Inglês | MEDLINE | ID: mdl-38164007

RESUMO

Objective: This study compared dentoskeletal and soft tissue changes with face mask (FM) therapy. Rapid maxillary expansion (RME) and alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocols were used with the two different types of expansion appliance, and their effects on the treatment outcome were investigated. Methods: The study consisted of 79 (37 and 42 patients in the RME and Alt-RAMEC groups with FM, respectively) patients who had received FM treatment. The effects of the RME/FM (20 female, 17 male) and Alt-RAMEC/FM (14 female, 28 male) protocols were evaluated using lateral cephalometric films. The chronological ages of the RME/FM and Alt-RAMEC/FM groups were 11.58 and 11.99 years, respectively. In addition, both groups were divided into two subgroups based on the design of the expansion appliance (Spolyar or full coverage type). Differences in all parameters were analyzed using Student's t-tests. Results: The maxilla significantly moved forward in both the RME/FM and Alt-RAMEC/FM groups (p<0.001). No significant skeletal differences were observed between the groups. Sagittal movement of the upper incisors significantly increased, and the lower incisors significantly retruded in both groups. While similar skeletal changes were found between the Spolyar and full-coverage appliance groups, the upper incisors protruded significantly more in the full-coverage type. Conclusion: RME/FM and Alt-RAMEC/FM therapies were found to be efficient for maxillary protraction and resulted in similar skeletal changes. A full-coverage expansion appliance produced a more upper incisor protrusion than a spherical-type appliance.

16.
J Orofac Orthop ; 84(Suppl 2): 56-64, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34463789

RESUMO

PURPOSE: To evaluate and compare patients' oxidative stress parameters and antioxidant status with fixed orthodontic appliances during the pubertal and postpubertal growth periods. METHODS: Saliva samples of 20 pubertal (mean age: 12.94 ± 0.34 years) and 20 postpubertal (mean age: 16.34 ± 0.45 years) patients were collected just before the application of fixed orthodontic appliances (T0), 4-5 h (T1), and 7 days (T2) after the initial orthodontic activation. Myeloperoxidase (MPO), nitric oxide (NO), 8­hydroxydeoxyguanosine (8-OHdG) levels, and superoxide dismutase (SOD) activity in the saliva were examined. Repeated measures analysis of variance (ANOVA), least significant difference (LSD) pairwise comparison, and independent sample t­tests were used to analyze the differences between the time points and growth periods, respectively. RESULTS: MPO levels in the saliva of patients in the pubertal period showed a significantly higher increase within the first days of treatment (T2-T1) than in patients in the postpubertal period (p < 0.05). The SOD antioxidant enzyme activity decreased in the samples from T0 to T1 in the patients in the pubertal and postpubertal groups and returned to baseline values (T0) at T2 (p < 0.01). No significant differences in the other biochemical parameters between groups were observed. CONCLUSIONS: Comparing the pubertal and postpubertal groups, orthodontic force application with fixed orthodontic appliances did not change the final levels (on day 7) of antioxidant status or oxidative stress markers, except for MPO in saliva.


Assuntos
Antioxidantes , Saliva , Humanos , Criança , Adolescente , Aparelhos Ortodônticos Fixos , Estresse Oxidativo , Puberdade , Superóxido Dismutase , Aparelhos Ortodônticos
17.
Cell Biochem Funct ; 30(5): 376-81, 2012 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-22113708

RESUMO

The aim of this study was to investigate the levels of the oxidant and antioxidant changes in orthodontic tooth movement and the effects of vitamin E on these parameters. For this purpose, 50 orthodontic patients (aged 13-18 years) required non-extracted treatment were divided randomly into the following groups: Control and Vitamin E. Same pre-adjusted appliances were applied to all patients, and vitamin E (300 mg day(-1)) was given during 1 month in vitamin E group. Gingival crevicular fluid was collected and periodontal indexes were recorded at the baseline and after 1 month. Lipid peroxidation (LP) levels as malonyldialdehyde, reduced glutathione (GSH) and glutathione peroxidase (GSH-Px), vitamin C and E levels were measured in the anterior and posterior regions of the dentition. After 1 month, orthodontic treatment LP levels increased in control group in both anterior and posterior regions in vitamin E group. LP levels also increased in vitamin E group in only posterior region. The level of GSH and vitamin C did not change statistically in control and vitamin E groups. Periodontal indexes did not show any differences in comparison with the groups. In conclusion, we observed protective role of vitamin E on LP levels in anterior region of patients with orthodontic tooth movement.


Assuntos
Antioxidantes/metabolismo , Suplementos Nutricionais , Líquido do Sulco Gengival/efeitos dos fármacos , Peroxidação de Lipídeos/efeitos dos fármacos , Técnicas de Movimentação Dentária , Vitamina E/administração & dosagem , Vitamina E/farmacologia , Adolescente , Ácido Ascórbico/metabolismo , Feminino , Líquido do Sulco Gengival/metabolismo , Glutationa/metabolismo , Glutationa Peroxidase/metabolismo , Humanos , Masculino , Malondialdeído/metabolismo , Vitamina E/metabolismo
18.
Cleft Palate Craniofac J ; 49(1): 60-72, 2012 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-21476830

RESUMO

OBJECTIVE: The objective of this study was to determine the developments, morphometric features, and shapes of the maxillary and mandibular arches during the prenatal period in a large series of fetal material. METHODS: The study was carried out on 225 human fetuses aged between 8 and 40 weeks of gestation. General, extraoral, and intraoral parameters were taken from each fetus. The width and depth measurements and the shapes of the maxillary and mandibular arches were achieved using the casts obtained. The arches were categorized according to the shapes of the anterior and posterior regions of the arches. RESULTS: Palatal and mandibular indices did not change during the prenatal period. Maxillary arch measurements were greater than the mandibular measurements. Moreover, width measurements of both arches were greater than the depth measurements during fetal life. We found that the frequencies of triangular maxillary and mandibular arches were highest in the first and second trimesters; whereas, the square model became more frequent in the third trimester and at full term. Classification of the arches according to their posterior regions showed that the tips of the arches shifted medially toward the term. There were significant correlations between width and depth parameters of the arches and extraoral parameters. CONCLUSION: Data obtained in the study would be useful for clinicians by presenting an objective scale related to the prenatal period as well as being helpful in assessing the development of this region, identifying the anomalies and pathologies, and assisting treatment.


Assuntos
Arco Dental/embriologia , Feto/embriologia , Mandíbula/embriologia , Maxila/embriologia , Antropometria , Cadáver , Feminino , Idade Gestacional , Humanos , Masculino , Modelos Anatômicos
19.
J Craniofac Surg ; 22(6): 2072-9, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22067862

RESUMO

OBJECTIVE: The aim of this study was to identify and quantify nasal profile changes following maxillary advancement (MA) and maxillary advancement with impaction (MAI) with Le Fort I osteotomies. METHODS: The study consisted of preoperative and postoperative lateral cephalograms of 42 class III adult patients. The study sample was divided into 2 groups, with the first group composed of 22 patients who underwent MA surgery and the second group composed of 20 patients who underwent MAI surgery. In total, 7 skeletal parameters and 17 soft-tissue parameters related to nasal projection, hump, dorsal convexity, and the nasolabial region were evaluated on the cephalograms, and hard- and soft-tissue relationships were assessed. RESULTS: Nasal length, hump, nasal depths, distance from the most convex point of the Alar curvature to the most inferior point of the nostril, alar curvature-subnasale, and subnasale-pronasale measurements decreased postoperatively. In the MAI group, MA correlated with significant decreases in nasal length and hump. In the MA group, MA correlated with pronasale position (P < 0.05); significant decreases in nasal depth, columella convexity, and subnasale-pronasale length; and significant changes in subnasale position. CONCLUSIONS: There is little difference in the effects of the 2 different maxillary surgeries on the postoperative nasal profile.


Assuntos
Má Oclusão Classe III de Angle/cirurgia , Maxila/cirurgia , Nariz/anatomia & histologia , Osteotomia de Le Fort , Adulto , Cefalometria , Feminino , Humanos , Masculino , Nariz/diagnóstico por imagem , Radiografia , Análise de Regressão , Estatísticas não Paramétricas , Resultado do Tratamento
20.
Clin Plast Surg ; 48(3): 419-429, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34051895

RESUMO

Alveolar distraction osteogenesis (ADO) has been used for the reconstruction of atrophic alveolus for decades. The advantage of this technique is that it augments the bone and soft tissues together, creating a better alveolar platform for subsequent surgeries and dental rehabilitation. It is especially useful in patients with large and/or complex alveolar clefts for which approximating the alveolar segments reduces the size of the bony cleft and associated fistula. Displacement of the transported segment is the most frequently encountered complication of ADO but can be managed by constructing case-specific distractors.


Assuntos
Enxerto de Osso Alveolar , Processo Alveolar/cirurgia , Alveoloplastia/métodos , Fissura Palatina/cirurgia , Osteogênese por Distração/métodos , Adolescente , Processo Alveolar/anormalidades , Humanos , Masculino , Ortodontia Corretiva/métodos , Osteogênese por Distração/instrumentação , Adulto Jovem
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