Detalhe da pesquisa
1.
Design of a novel pyrrolidine scaffold utilized in the discovery of potent and selective human ß3 adrenergic receptor agonists.
Bioorg Med Chem Lett
; 21(6): 1865-70, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21353541
2.
Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles.
Bioorg Med Chem Lett
; 20(6): 1895-9, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20181479
3.
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Bioorg Med Chem Lett
; 20(6): 1913-7, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167483
4.
Discovery and optimization of novel 4-[(aminocarbonyl)amino]-N-[4-(2-aminoethyl)phenyl]benzenesulfonamide ghrelin receptor antagonists.
Bioorg Med Chem Lett
; 19(21): 6237-40, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19767208
5.
Increased melanin concentrating hormone receptor type I in the human hypothalamic infundibular nucleus in cachexia.
J Clin Endocrinol Metab
; 90(4): 2412-9, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15671106
6.
Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats.
Eur J Pharmacol
; 475(1-3): 37-47, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12954357
7.
4-Aminoquinoline melanin-concentrating hormone 1-receptor (MCH1R) antagonists.
Bioorg Med Chem Lett
; 16(20): 5275-9, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16919453
8.
2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists.
Bioorg Med Chem Lett
; 16(20): 5270-4, 2006 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16919456
9.
Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.
Biochemistry
; 41(20): 6383-90, 2002 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12009900
10.
Characterization of the bombesin-like peptide receptor family in primates.
Genomics
; 84(1): 139-46, 2004 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-15203211
11.
Synthesis and biological evaluation in vitro of a selective, high potency peptide agonist of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1.
J Biol Chem
; 277(16): 13821-6, 2002 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-11839762
12.
Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression.
Genomics
; 79(6): 785-92, 2002 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12036292