Detalhe da pesquisa
1.
Exposure-Efficacy Analyses Support Optimal Dosing Regimens of Ceftolozane/Tazobactam in Participants with Hospital-Acquired/Ventilator-Associated Bacterial Pneumonia in ASPECT-NP.
Antimicrob Agents Chemother
; 66(5): e0139921, 2022 05 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35471040
2.
Population Pharmacokinetics, Exposure-Response, and Probability of Target Attainment Analyses for Tedizolid in Adolescent Patients with Acute Bacterial Skin and Skin Structure Infections.
Antimicrob Agents Chemother
; 65(12): e0089521, 2021 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34516243
3.
Ceftolozane/tazobactam probability of target attainment and outcomes in participants with augmented renal clearance from the randomized phase 3 ASPECT-NP trial.
Crit Care
; 25(1): 354, 2021 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34600585
4.
Outcomes in Participants with Renal Impairment from a Phase 3 Clinical Trial for Ceftolozane/Tazobactam Treatment of Nosocomial Pneumonia (ASPECT-NP).
Antimicrob Agents Chemother
; 64(12)2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32988827
5.
Use of Translational Pharmacokinetic/Pharmacodynamic Infection Models To Understand the Impact of Neutropenia on the Efficacy of Tedizolid Phosphate.
Antimicrob Agents Chemother
; 63(1)2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30373794
6.
Pharmacokinetic Interactions between the Hepatitis C Virus Inhibitors Elbasvir and Grazoprevir and HIV Protease Inhibitors Ritonavir, Atazanavir, Lopinavir, and Darunavir in Healthy Volunteers.
Antimicrob Agents Chemother
; 63(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30745392
7.
Assessment of drug interaction potential between the HCV direct-acting antiviral agents elbasvir/grazoprevir and the HIV integrase inhibitors raltegravir and dolutegravir.
J Antimicrob Chemother
; 74(3): 710-717, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30541077
8.
Pharmacokinetics of elbasvir and grazoprevir in subjects with end-stage renal disease or severe renal impairment.
Eur J Clin Pharmacol
; 75(5): 665-675, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30680407
9.
Population pharmacokinetics of tazobactam/ceftolozane in Japanese patients with complicated urinary tract infection and complicated intra-abdominal infection.
J Infect Chemother
; 25(3): 182-191, 2019 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-30528208
10.
No clinically meaningful pharmacokinetic interaction between the hepatitis C virus inhibitors elbasvir and grazoprevir and the oral contraceptives ethinyl estradiol and levonorgestrel.
Eur J Clin Pharmacol
; 73(5): 593-600, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233047
11.
Pharmacokinetic interaction between HCV protease inhibitor boceprevir and methadone or buprenorphine in subjects on stable maintenance therapy.
Eur J Clin Pharmacol
; 71(3): 303-11, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25666027
12.
Pharmacokinetic and pharmacodynamic interactions between the hepatitis C virus protease inhibitor, boceprevir, and the oral contraceptive ethinyl estradiol/norethindrone.
Eur J Clin Pharmacol
; 70(9): 1107-13, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24992979
13.
Pharmacokinetic interactions between the hepatitis C virus protease inhibitor boceprevir and ritonavir-boosted HIV-1 protease inhibitors atazanavir, darunavir, and lopinavir.
Clin Infect Dis
; 56(5): 718-26, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23155151
14.
Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers.
Hepatology
; 56(5): 1622-30, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22576324
15.
Probability of Target Attainment Analyses to Inform Ceftolozane/Tazobactam Dosing Regimens for Patients With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia and End-Stage Renal Disease Receiving Intermittent Hemodialysis.
J Clin Pharmacol
; 63(2): 166-171, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36046982
16.
Effects of an inhaled soluble guanylate cyclase (sGC) stimulator MK-5475 in pulmonary arterial hypertension (PAH).
Respir Med
; 206: 107065, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521262
17.
A single- and multiple-dose study to characterize the pharmacokinetics, safety, and tolerability of ceftolozane/tazobactam in healthy Chinese participants.
Int J Antimicrob Agents
; 61(3): 106717, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-36640850
18.
Ceftolozane/Tazobactam Probability of Target Attainment in Patients With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia.
J Clin Pharmacol
; 63(3): 352-357, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36201105
19.
Population Pharmacokinetic Analysis for Plasma and Epithelial Lining Fluid Ceftolozane/Tazobactam Concentrations in Patients With Ventilated Nosocomial Pneumonia.
J Clin Pharmacol
; 61(2): 254-268, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32949031
20.
Evaluation of Pharmacokinetic Drug Interactions of the Direct-Acting Antiviral Agents Elbasvir and Grazoprevir with Pitavastatin, Rosuvastatin, Pravastatin, and Atorvastatin in Healthy Adults.
Clin Drug Investig
; 41(2): 133-147, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33527237