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1.
Eur J Clin Microbiol Infect Dis ; 34(12): 2331-8, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26432552

RESUMO

Surgical site infection is a common complication following cardiac surgery. Triclosan-coated sutures have been shown to reduce the rate of infections in various surgical wounds, including wounds after vein harvesting in coronary artery bypass grafting patients. Our purpose was to compare the rate of infections in sternotomy wounds closed with triclosan-coated or conventional sutures. A total of 357 patients that underwent coronary artery bypass grafting were included in a prospective randomized double-blind single-center study. The patients were randomized to closure of the sternal wound with either triclosan-coated sutures (Vicryl Plus and Monocryl Plus, Ethicon, Inc., Somerville, NJ, USA) (n = 179) or identical sutures without triclosan (n = 178). Patients were followed up after 30 days (clinical visit) and 60 days (telephone interview). The primary endpoint was the prevalence of sternal wound infection according to the Centers for Disease Control and Prevention (CDC) criteria. The demographics in both groups were comparable, including age, gender, body mass index, and rate of diabetes and smoking. Sternal wound infection was diagnosed in 43 patients; 23 (12.8%) sutured with triclosan-coated sutures compared to 20 (11.2%) sutured without triclosan (p = 0.640). Most infections were superficial (n = 36, 10.1%), while 7 (2.0%) were deep sternal wound infections. There were 16 positive cultures in the triclosan group and 17 in the non-coated suture group (p = 0.842). The most commonly identified main pathogens were Staphylococcus aureus (45.4%) and coagulase-negative staphylococci (36.4%). Skin closure with triclosan-coated sutures did not reduce the rate of sternal wound infection after coronary artery bypass grafting. (clinicaltrials.gov: NCT01212315).


Assuntos
Anti-Infecciosos Locais/administração & dosagem , Ponte de Artéria Coronária/efeitos adversos , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Técnicas de Sutura , Suturas , Triclosan/administração & dosagem , Idoso , Bactérias/classificação , Bactérias/isolamento & purificação , Método Duplo-Cego , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Prospectivos , Resultado do Tratamento
2.
Eur J Clin Microbiol Infect Dis ; 33(11): 1981-7, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24907853

RESUMO

The aim of the present study was to compare microbial skin sealant versus bare skin on the leg regarding intraoperative bacterial presence in the surgical wound and time to recolonization of the adjacent skin at the saphenous vein harvesting site. A second aim was to evaluate the incidence of leg wound infection 2 months after surgery. In this randomized controlled trial, 140 patients undergoing coronary artery bypass grafting (CABG) between May 2010 and October 2011 were enrolled. Bacterial samples were taken preoperatively and intraoperatively at multiple time points and locations. OF the patients, 125 (92.6 %) were followed up 2 months postoperatively regarding wound infection. Intraoperative bacterial growth did not differ between the bare skin (n = 68) and the microbial skin sealant group (n = 67) at any time point. At 2 months postoperatively, 7/61 patients (11.5 %) in the skin sealant versus 14/64 (21.9 %) in the bare skin group (p = 0.120) had been treated with antibiotics for a verified or suspected surgical site infection (SSI) at the harvest site. We found almost no intraoperative bacterial presence on the skin or in the subcutaneous tissue, irrespective of microbial skin sealant use. In contrast, we observed a relatively high incidence of late wound infection, indicating that wound contamination occurred postoperatively. Further research is necessary to determine whether the use of microbial skin sealant reduces the incidence of leg wound infection at the saphenous vein harvest site.


Assuntos
Ponte de Artéria Coronária/efeitos adversos , Controle de Infecções/métodos , Cuidados Pré-Operatórios/métodos , Pele/microbiologia , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/prevenção & controle , Ferimentos e Lesões/microbiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Veia Safena , Adulto Jovem
3.
Br J Anaesth ; 113(1): 75-82, 2014 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-24727704

RESUMO

BACKGROUND: Postoperative heart failure remains the major cause of death after cardiac surgery. As N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a predictor for postoperative heart failure, the aim was to evaluate if preoperative NT-proBNP could provide additional prognostic information to the recently launched EuroSCORE II. METHODS: A total of 365 patients with acute coronary syndrome (ACS) undergoing isolated coronary artery bypass graft (CABG) surgery were studied prospectively. Preoperative NT-proBNP and EuroSCORE II were evaluated with regard to severe circulatory failure after operation according to prespecified criteria. To assess what clinical outcomes are indicated by NT-proBNP levels in different risk categories, the patients were stratified according to EuroSCORE II. Based on receiver operating characteristics analysis, these cohorts were assessed with regard to preoperative NT-proBNP below or above 1028 ng litre(-1). The follow-up time averaged 4.4 (0.7) yr. RESULTS: Preoperative NT-proBNP≥1028 ng litre(-1) [odds ratio (OR) 9.9, 95% confidence interval (CI) 1.01-98.9; P=0.049] and EuroSCORE II (OR 1.24, 95% CI 1.06-1.46; P=0.008) independently predicted severe circulatory failure after operation. In intermediate-risk patients (EuroSCORE II 2.0-10.0), NT-proBNP≥1028 ng litre(-1) was associated with a higher incidence of severe circulatory failure (6.6% vs 0%; P=0.007), renal failure (14.8% vs 5.4%; P=0.03), stroke (6.6% vs 0.7%; P=0.03), longer intensive care unit stay [37 (35) vs 27 (38) h; P=0.002], and worse long-term survival. CONCLUSIONS: Combining EuroSCORE II and preoperative NT-proBNP appears to improve risk prediction with regard to severe circulatory failure after isolated CABG for ACS. NT-proBNP may be particularly useful in patients at intermediate risk according to EuroSCORE II. CLINICAL TRIAL REGISTRATION: NCT00489827.


Assuntos
Síndrome Coronariana Aguda/cirurgia , Ponte de Artéria Coronária/efeitos adversos , Peptídeo Natriurético Encefálico/sangue , Fragmentos de Peptídeos/sangue , Síndrome Coronariana Aguda/sangue , Síndrome Coronariana Aguda/diagnóstico , Síndrome Coronariana Aguda/mortalidade , Adulto , Idoso , Idoso de 80 Anos ou mais , Biomarcadores/sangue , Ponte de Artéria Coronária/mortalidade , Feminino , Mortalidade Hospitalar , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Cuidados Pré-Operatórios/métodos , Prognóstico , Estudos Prospectivos , Medição de Risco/métodos , Índice de Gravidade de Doença , Choque/etiologia , Choque/mortalidade , Suécia/epidemiologia , Resultado do Tratamento
4.
J Hosp Infect ; 135: 145-151, 2023 May.
Artigo em Inglês | MEDLINE | ID: mdl-37004786

RESUMO

BACKGROUND: Sternal wound infections (SWIs) and aortic graft infections (AGIs) are serious complications after cardiac surgery. Staphylococcus aureus and coagulase-negative staphylococci are the most common causes of SWIs, whereas AGIs are less studied. AGIs may occur from contamination during surgery or postoperative haematogenous spread. Skin commensals, such as Cutibacterium acnes, are present in the surgical wound; however, their ability to cause infection is debated. AIM: To investigate the presence of skin bacteria in the sternal wound and to evaluate their potential to contaminate surgical materials. METHODS: Fifty patients undergoing coronary artery bypass graft surgery and/or valve replacement surgery at Örebro University Hospital from 2020 to 2021 were included. Cultures were collected from skin and subcutaneous tissue at two timepoints during surgery, and from pieces of vascular graft and felt that were pressed against subcutaneous tissue. The most common bacterial isolates were tested for antibiotic susceptibility with disc diffusion and gradient tests. FINDINGS: Cultures from skin had bacterial growth in 48% of patients at surgery start and in 78% after 2 h, and cultures from subcutaneous tissue were positive in 72% and 76% of patients, respectively. The most common isolates were C. acnes and S. epidermidis. Cultures from surgical materials were positive in 80-88%. No difference in susceptibility was found for S. epidermidis isolates at surgery start compared with after 2 h. CONCLUSION: The results suggest that skin bacteria are present in the wound and may contaminate surgical graft material during cardiac surgery.


Assuntos
Procedimentos Cirúrgicos Cardíacos , Infecções Estafilocócicas , Cirurgia Torácica , Humanos , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/microbiologia , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Staphylococcus , Infecções Estafilocócicas/microbiologia , Complicações Pós-Operatórias/microbiologia , Staphylococcus epidermidis
5.
Br J Anaesth ; 108(2): 216-22, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22113929

RESUMO

BACKGROUND: Re-exploration for bleeding after cardiac surgery is an indicator of substantial haemorrhage and is associated with increased hospital resource utilization. This study aimed to analyse the costs of re-exploration and estimate the costs of haemostatic prophylaxis. METHODS: A total of 4232 patients underwent isolated, first-time, coronary artery bypass graft (CABG) surgery during 2005-8. Each patient re-explored for bleeding (n=127) was matched with two controls not requiring re-exploration (n=254). Cost analysis was based on resource utilization from completion of CABG until discharge. A mean cost per patient for re-exploration was calculated. Based on this, the net cost of prophylactic treatment with haemostatic drugs for preventing re-exploration was calculated. RESULTS: Patients undergoing re-exploration had higher exposure to clopidogrel before operation, prolonged stays in the intensive care unit, and more blood transfusions than controls. The mean incremental cost for re-exploration was €6290 [95% confidence interval (CI) €3408-€9173] per patient, of which 48% [€3001 (95% CI €249-€2147)] was due to prolonged stay, 31% [€1928 (95% CI €1710-€2147)] to the cost of surgery/anaesthesia, 20% [€1261 (95% CI €1145-€1378)] to the increased number of blood transfusions, and <2% [€100 (95% CI €39-€161)] to the cost of haemostatic drugs. A cost model, at an estimated 50% efficacy for recombinant activated clotting factor VIIa and a 50% expected risk for re-exploration without prophylaxis, demonstrated that to be cost neutral, prophylaxis of four patients needed to result in one avoided re-exploration. CONCLUSIONS: The resource utilization costs were substantially higher in patients requiring re-exploration for bleeding. From a strict cost-effectiveness perspective, clinical interventions to prevent haemorrhage might be underutilized.


Assuntos
Ponte de Artéria Coronária/economia , Hemorragia Pós-Operatória/economia , Idoso , Estudos de Casos e Controles , Ponte de Artéria Coronária/efeitos adversos , Análise Custo-Benefício , Custos de Medicamentos/estatística & dados numéricos , Fator VIIa/economia , Fator VIIa/uso terapêutico , Feminino , Recursos em Saúde/economia , Recursos em Saúde/estatística & dados numéricos , Hemostasia Cirúrgica/economia , Hemostasia Cirúrgica/métodos , Hemostáticos/economia , Hemostáticos/uso terapêutico , Custos Hospitalares/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Modelos Econométricos , Hemorragia Pós-Operatória/etiologia , Hemorragia Pós-Operatória/prevenção & controle , Hemorragia Pós-Operatória/cirurgia , Proteínas Recombinantes/economia , Proteínas Recombinantes/uso terapêutico , Reoperação/economia , Suécia , Resultado do Tratamento
6.
Spine (Phila Pa 1976) ; 8(6): 643-51, 1983 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-6228021

RESUMO

A simple and reliable low dose radiologic method developed by the author was used to measure leg length inequality of 798 patients with chronic and therapy resistant low-back and/or unilateral hip symptoms and 359 symptom free subjects. Statistically highly significant correlations of the symptoms and leg length inequality were observed. In the majority (79 and 89%), the chronic or recurrent sciatic pain and unilateral hip symptoms occurred on the side of the longer lower extremity. When correcting the leg length inequality simply with an adequate shoe lift, a permanent and mostly complete alleviation of symptoms was achieved in the majority of the cases. The unilateral symptoms associated with mostly unrecognized leg length inequality of 5 to 25 mm were, at least in part, due to the biomechanical responses, like bending and rotational forces, needed for compensation of the lateral imbalance caused by leg length inequality.


Assuntos
Dor nas Costas/etiologia , Articulação do Quadril/fisiopatologia , Desigualdade de Membros Inferiores/fisiopatologia , Vértebras Lombares/fisiopatologia , Ciática/etiologia , Adolescente , Adulto , Idoso , Dor nas Costas/terapia , Humanos , Pessoa de Meia-Idade , Aparelhos Ortopédicos , Postura , Rotação , Ciática/terapia , Sapatos , Doenças da Coluna Vertebral/fisiopatologia , Estresse Mecânico
7.
Spine (Phila Pa 1976) ; 12(2): 119-29, 1987 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-2954216

RESUMO

Translatory segmental instability was provoked by successive axial traction and compression of the lumbar spine in 117 patients with a known spondyl- or retro-olisthetic displacement. Lateral spot radiography showed an anteroposterior translatory movement of 5 mm or more in 24 of 45 patients with lytic spondylolisthesis of L5, in all of 7 patients with degenerative spondylolisthesis of L4, and in 37 of 65 patients with a retro-olisthetic displacement of L3, L4, or L5. In cases of spondyl- and retro-olisthetic instability the upper vertebra moved posteriorly during traction and anteriorly during compression. Severity of low-back pain (LBP) symptoms did not show any correlation with the degree of the maximal displacement but correlated significantly with the amount of instability both in the case of spondyl- and retro-olisthesis. Traction-compression radiography proved a simple and practical method to diagnose and measure translatory segmental instability even when conventional flexion-extension load failed to provoke any abnormal movement (eg, in the case of spondylolisthesis).


Assuntos
Instabilidade Articular/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Doenças da Coluna Vertebral/diagnóstico por imagem , Adolescente , Adulto , Idoso , Dor nas Costas/diagnóstico por imagem , Dor nas Costas/fisiopatologia , Feminino , Humanos , Deslocamento do Disco Intervertebral/diagnóstico por imagem , Deslocamento do Disco Intervertebral/fisiopatologia , Instabilidade Articular/fisiopatologia , Lordose/diagnóstico por imagem , Lordose/fisiopatologia , Vértebras Lombares/fisiopatologia , Masculino , Pessoa de Meia-Idade , Movimento , Postura , Radiografia , Doenças da Coluna Vertebral/fisiopatologia , Espondilolistese/diagnóstico por imagem , Espondilolistese/fisiopatologia , Espondilólise/diagnóstico por imagem , Espondilólise/fisiopatologia , Tração
8.
Clin Biomech (Bristol, Avon) ; 2(4): 211-9, 1987 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23915757

RESUMO

Standing orthoradiography of the lumbar spine, the hip and knee joints revealed a lateral lumbar curve of 5-22° (mean=9·0°, s.d.=4·2°) secondary to leg length inequality in 186 or 64·6% of 288 consecutive patients with chronic low back pain (LBP). The incidence of leg length inequality in LBP patients (mean=10·6mm, s.d.=6·7mm) was significantly higher (P<0·001) than in 366 asymptomatic controls (mean=5·1 mm, s.d.=2·4 mm). In 170 cases (91·4%), the lumbar curve was convex toward the short leg side, correlating significantly with the degree of lateral inclination of the sacrum (r=+0·97) and with the amount of leg length inequality (r=-0·81). The curvature was generally coupled with an axial rotation of the vertebrae moving the spinous processes toward the concavity, as well as with an opposite rotation of the pelvis (r=+0·77), which were calculated to result in a significant torsional stress on the L5-S1 segment.

9.
BMJ ; 311(7021): 1661-3, 1995.
Artigo em Inglês | MEDLINE | ID: mdl-8541749

RESUMO

OBJECTIVE: To determine the incidence of and the risk factors for local cold injuries of the face and ears in peacetime military service. DESIGN: Prospective, controlled epidemiological study using a questionnaire. SETTING: Finnish defence forces, 1976-89. SUBJECTS: 913 young male conscripts with local frostbite of the head that needed medical attention and 2478 uninjured control conscripts. MAIN OUTCOME MEASURES: Type of activity, clothing, and other risk factors at the time of cold injury. Odds ratios were used to calculate risk. Controls were handled as one group. RESULTS: The mean annual incidence of frostbite was 1.8 per 1000 conscripts. Frostbite of the ear was most common (533 conscripts (58%)), followed by frostbite of the nose (197 (22%)) and of the cheeks and other regions of the face (183 (20%)). Most conscripts (803 (88%)) had mild or superficial frostbite. Risk factors included not wearing a hat with earflaps (odds ratio 18.5 for frostbite of the ear); not wearing a scarf (odds ratio 2.1 and 3.8 for frostbite of the ear and cheeks respectively); using protective ointments (odds ratio 3.3, 4.5, and 5.6 for frostbite of the cheeks, ear, and nose respectively); being extremely sensitive to cold and having hands and feet that sweat profusely (odds ratio 3.5 for frostbite of the nose); and being transported in the open or in open vehicles under windy conditions (odds ratio 2.2 for frostbite of the cheek). CONCLUSIONS: Wearing warm clothing, including a scarf and a hat with earflaps, helps to prevent frostbite. Each person's sensitivity to cold may also be important. The routine use of protective ointments should not be recommended.


Assuntos
Congelamento das Extremidades/epidemiologia , Militares , Adulto , Finlândia/epidemiologia , Humanos , Incidência , Masculino , Prevalência , Estudos Prospectivos , Roupa de Proteção , Fatores de Risco
10.
Orthopedics ; 14(4): 463-5, 1991 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-2038581

RESUMO

Anteroposterior translation as a sign of segmental instability was documented by traction-compression radiography in the majority of lumbar segments presenting lytic or degenerative spondylolisthesis with normal disc space height. Severity of lower back pain symptoms correlated with the degree of instability, but not with the amount of static spondylolisthetic displacement. Unstable spondylolistheses exhibited decreased viscoelastic behavior with creep, the degree of the vertebral displacement being dependent on the amount and duration of load. Disc degeneration and traction spurs seemed to be factors that may stabilize spondylolisthesis, even at an early age.


Assuntos
Instabilidade Articular/fisiopatologia , Espondilolistese/fisiopatologia , Fenômenos Biomecânicos , Humanos , Instabilidade Articular/diagnóstico por imagem , Vértebras Lombares , Radiografia , Espondilolistese/diagnóstico por imagem , Tecnologia Radiológica
11.
Prosthet Orthot Int ; 8(3): 124-9, 1984 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-6240634

RESUMO

The length of the lower limb prosthesis was compared with the length of the contralateral lower extremity in 113 Finnish war-disabled amputees by a radiological weight bearing method developed by the author. Considering a shortening of 10 mm for above-knee prostheses and of 5 mm for below-knee prostheses as tolerance limits, the length of the prosthesis was acceptable only in 17 cases (15% of the total group). In 79 cases (70%) the prosthesis was up to 47 mm too short and in 17 cases (15%) up to 40 mm too long. Chronic pain symptoms of low back, hip and knee correlated significantly with the lateral asymmetry caused by incorrect length of the prosthesis. Independently of the side of amputation, the unilateral sciatica and chronic hip pain occurred mainly on the long leg side. Physical activity of the lower limb amputees seemed to correlate with the suitability of the length of the prosthesis, and was unrelated to the length of the amputation stump.


Assuntos
Membros Artificiais , Idoso , Dor nas Costas/etiologia , Fenômenos Biomecânicos , Articulação do Quadril/fisiopatologia , Humanos , Artropatias/etiologia , Articulação do Joelho/fisiopatologia , Perna (Membro) , Pessoa de Meia-Idade , Dor/etiologia , Desenho de Prótese , Esportes
12.
J Hosp Infect ; 84(2): 151-8, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23623487

RESUMO

BACKGROUND: Sternal wound infection after cardiac surgery is a serious complication. Various perioperative strategies, including plastic adhesive drapes, are used to reduce bacterial contamination of surgical wounds. AIM: To compare plastic adhesive drape to bare skin regarding bacterial growth in wound and time to recolonization of the adjacent skin intraoperatively, in cardiac surgery patients. METHODS: This single-blinded randomized controlled trial (May 2010 to May 2011) included 140 patients scheduled for cardiac surgery via median sternotomy. The patients were randomly allocated to the adhesive drape (chest covered with plastic adhesive drape) or bare skin group. Bacterial samples were taken preoperatively and intraoperatively every hour during surgery until skin closure. RESULTS: Disinfection with 0.5% chlorhexidine solution in 70% alcohol decreased coagulase-negative staphylococci (CoNS), while the proportion colonized with Propionibacterium acnes was not significantly reduced and was still present in more than 50% of skin samples. P. acnes was significantly more common in men than in women. Progressive bacterial recolonization of the skin occurred within 2-3 h. At 120 min there were significantly more positive cultures in the adhesive drape group versus bare skin group for P. acnes (63% vs 44%; P = 0.034) and for CoNS (45% vs 24%; P = 0.013). The only statistically significant difference in bacterial growth in the surgical wound was higher proportion of CoNS at the end of surgery in the adhesive drape group (14.7% vs 4.4%; P = 0.044). CONCLUSION: Plastic adhesive drape does not reduce bacterial recolonization. P. acnes colonized men more frequently, and was not decreased by disinfection with chlorhexidine solution in alcohol.


Assuntos
Desinfecção/métodos , Complicações Pós-Operatórias/prevenção & controle , Cuidados Pré-Operatórios/métodos , Pele/microbiologia , Cirurgia Torácica/métodos , Ferimentos e Lesões/microbiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias/microbiologia , Método Simples-Cego , Resultado do Tratamento , Adulto Jovem
17.
Eur J Clin Microbiol Infect Dis ; 26(2): 91-7, 2007 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-17211605

RESUMO

Sternal wound infection (SWI) is a serious complication after cardiac surgery. In a previous randomized controlled trial, the addition of local collagen-gentamicin in the sternal wound before wound closure was found to significantly reduce the incidence of postoperative wound infections compared with the routine intravenous prophylaxis of isoxazolyl-penicillin only. The aims of the present study were to analyse the microbiological findings of the SWIs from the previous trial as well as to correlate these findings with the clinical presentation of SWI. Differences in clinical presentation of SWIs, depending on the causative agent, could be identified. Most infections had a late, insidious onset, and the majority of these were caused by staphylococci, predominantly coagulase-negative staphylococci. The clinically most fulminant infections were caused by gram-negative bacteria and presented early after surgery. Local administration of gentamicin reduced the incidence of SWIs caused by all major, clinically important bacterial species. Propionibacterium acnes was identified as a possible cause of SWI and may be linked to instability in the sternal fixation. There was no indication of an increase in the occurrence of gentamicin-resistant bacterial isolates in the treatment group. Furthermore, the addition of local collagen-gentamicin reduced the incidence of SWIs caused by methicillin-resistant coagulase-negative staphylococci. This technique warrants further evaluation as an alternative to prophylactic vancomycin in settings with a high prevalence of methicillin-resistant Staphylococcus aureus.


Assuntos
Antibacterianos/uso terapêutico , Antibioticoprofilaxia , Infecções Bacterianas/epidemiologia , Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Gentamicinas/uso terapêutico , Esterno/cirurgia , Infecção da Ferida Cirúrgica/epidemiologia , Antibioticoprofilaxia/economia , Infecções Bacterianas/microbiologia , Bactérias Gram-Negativas/classificação , Bactérias Gram-Negativas/isolamento & purificação , Bactérias Gram-Negativas/patogenicidade , Humanos , Incidência , Propionibacterium acnes/classificação , Propionibacterium acnes/isolamento & purificação , Propionibacterium acnes/patogenicidade , Staphylococcus/classificação , Staphylococcus/isolamento & purificação , Staphylococcus/patogenicidade , Infecção da Ferida Cirúrgica/microbiologia , Infecção da Ferida Cirúrgica/fisiopatologia , Resultado do Tratamento
18.
Thorac Cardiovasc Surg ; 54(7): 468-73, 2006 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-17089314

RESUMO

BACKGROUND: The aim of the present study was to examine the influence of the number of sternal fixation wires used on deep sternal wound infection rate and to analyze any possible interaction between this and local collagen-gentamicin prophylaxis evaluated in a previous trial. METHODS: The number of sternal fixation wires in all patients from one of two participating centers was counted. The patients were categorized according to six or fewer (standard technique, ST group) vs. seven or more wires (extra wires, XW group). RESULTS: The incidence of deep sternal wound infection was 4.2 % in the ST group and 0.4 % in the XW group ( P = 0.001). An analysis of the effect of local gentamicin, excluding the ST group from the analysis, showed an approximately 70 % reduction in sternal wound infection for all depths. CONCLUSION: This study supports the theory that additional fixation wires at the lower sternum actually reduce the incidence of deep wound infections. We suggest that a rigid sternal fixation is required to achieve the full benefit of local collagen-gentamicin prophylaxis.


Assuntos
Fios Ortopédicos , Procedimentos Cirúrgicos Cardiovasculares , Esterno/cirurgia , Infecção da Ferida Cirúrgica/prevenção & controle , Toracotomia , Idoso , Antibioticoprofilaxia , Colágeno/uso terapêutico , Ponte de Artéria Coronária , Gentamicinas/uso terapêutico , Humanos , Incidência , Deiscência da Ferida Operatória/prevenção & controle , Infecção da Ferida Cirúrgica/epidemiologia , Técnicas de Sutura , Suécia/epidemiologia
19.
Eur J Vasc Endovasc Surg ; 30(2): 147-51, 2005 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-15996601

RESUMO

Endovascular repair of thoracic aneurysms has emerged as an attractive alternative especially in patients at high risk. However, the left common carotid artery limits the use of stent-grafts in aneurysms located in the aortic arch or close to the left subclavian artery. We report two cases with aneurysms in the distal arch and proximal descending aorta, where we have used a carotid stent in juxtaposition to an aortic stent-graft, to gain a longer proximal neck in the aortic arch in an attempt not to rely only on a by-pass graft feeding the left carotid artery.


Assuntos
Angioplastia/métodos , Aneurisma da Aorta Torácica/cirurgia , Artéria Carótida Primitiva/cirurgia , Stents , Idoso , Aneurisma da Aorta Torácica/diagnóstico por imagem , Artéria Carótida Primitiva/diagnóstico por imagem , Humanos , Masculino , Radiografia , Artéria Subclávia/diagnóstico por imagem , Artéria Subclávia/cirurgia
20.
Ann Med ; 21(5): 341-6, 1989 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-2532523

RESUMO

Functional methods utilising the effects of gravity on the upright lordotic spine were developed for both static and dynamic radiography. Static standing orthoradiography of the lumbar spine and weight-bearing joints of the lower extremities shows constitutional and functional abnormalities not visible in conventional recumbent radiography, e.g., postural scoliosis, hypo- or hyperlordosis, "kissing spine"-syndrome and signs of segmental instability. In dynamic traction-compression radiography segmental instability is provoked by axial traction and compression of the spine. With this method translatory instability of 5 to 15 mm was found in about half of the patients with lytic spondylolisthesis of L5 for which flexion-extension radiography had consistently failed to produce any abnormal movement. The amount of anterior spondylolisthetic and posterior retro-olisthetic instability correlated significantly with the severity of back pain symptoms, the degree of maximal static slip, however, being without significance. Functional radiography showed positive findings in most patients suffering from chronic low back pain of otherwise unknown aetiology.


Assuntos
Dor nas Costas/diagnóstico por imagem , Vértebras Lombares/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Dor nas Costas/fisiopatologia , Feminino , Humanos , Vértebras Lombares/fisiopatologia , Masculino , Pessoa de Meia-Idade , Movimento , Pressão , Radiografia , Espondilolistese/diagnóstico por imagem , Espondilolistese/fisiopatologia , Tração
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