Detalhe da pesquisa
1.
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Proc Natl Acad Sci U S A
; 121(18): e2400752121, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38648484
2.
Lamin A/C Ablation Restricted to Vascular Smooth Muscle Cells, Cardiomyocytes, and Cardiac Fibroblasts Causes Cardiac and Vascular Dysfunction.
Int J Mol Sci
; 24(13)2023 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446344
3.
Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome.
Circulation
; 144(22): 1777-1794, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34694158
4.
Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome.
Circulation
; 138(3): 266-282, 2018 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29490993
5.
A personalized intervention to prevent depression in primary care: cost-effectiveness study nested into a clustered randomized trial.
BMC Med
; 16(1): 28, 2018 02 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29471877
6.
Intervention to Prevent Major Depression in Primary Care: A Cluster Randomized Trial.
Ann Intern Med
; 164(10): 656-65, 2016 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27019334
7.
An EMMPRIN-γ-catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions.
J Cell Sci
; 127(Pt 17): 3768-81, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24994937
8.
ECO-physiological response of S. vulgaris to CR(VI): Influence of concentration and genotype.
Int J Phytoremediation
; 18(6): 567-74, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26375321
9.
Coronary and carotid artery dysfunction and KV7 overexpression in a mouse model of Hutchinson-Gilford progeria syndrome.
Geroscience
; 46(1): 867-884, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37233881
10.
The protease MT1-MMP drives a combinatorial proteolytic program in activated endothelial cells.
FASEB J
; 26(11): 4481-94, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22859368
11.
Preventing the onset of major depression based on the level and profile of risk of primary care attendees: protocol of a cluster randomised trial (the predictD-CCRT study).
BMC Psychiatry
; 13: 171, 2013 Jun 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782553
12.
Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression.
Proc Natl Acad Sci U S A
; 107(23): 10626-31, 2010 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20498053
13.
Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome.
Cardiovasc Res
; 118(2): 503-516, 2022 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33624748
14.
Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome.
ACS Cent Sci
; 7(8): 1300-1310, 2021 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34471675
15.
MT1-MMP collagenolytic activity is regulated through association with tetraspanin CD151 in primary endothelial cells.
Blood
; 112(8): 3217-26, 2008 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18663148
16.
Premature Vascular Aging with Features of Plaque Vulnerability in an Atheroprone Mouse Model of Hutchinson-Gilford Progeria Syndrome with Ldlr Deficiency.
Cells
; 9(10)2020 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049978
17.
Macrophages promote endothelial-to-mesenchymal transition via MT1-MMP/TGFß1 after myocardial infarction.
Elife
; 92020 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33063665
18.
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.
EMBO Mol Med
; 12(2): e10862, 2020 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31793743
19.
Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells.
EMBO Mol Med
; 11(4)2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30862662
20.
Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome.
Cell Discov
; 5: 16, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30911407