Detalhe da pesquisa
1.
Targeting metaplasticity mechanisms to promote sustained antidepressant actions.
Mol Psychiatry
; 29(4): 1114-1127, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38177353
2.
NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine.
J Neurosci
; 43(6): 1038-1050, 2023 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36596696
3.
cAMP-dependent protein kinase signaling is required for (2R,6R)-hydroxynorketamine to potentiate hippocampal glutamatergic transmission.
J Neurophysiol
; 131(1): 64-74, 2024 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050689
4.
Hydroxynorketamines: Pharmacology and Potential Therapeutic Applications.
Pharmacol Rev
; 73(2): 763-791, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33674359
5.
κ-Opioid Receptor Plasma Levels Are Associated With Sex and Diagnosis of Major Depressive Disorder But Not Response to Ketamine.
J Clin Psychopharmacol
; 43(2): 89-96, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36821406
6.
Blood-based biomarkers of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis.
Mol Psychiatry
; 27(9): 3658-3669, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35760879
7.
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search.
Mol Psychiatry
; 27(10): 4144-4156, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35768639
8.
Rare variants implicate NMDA receptor signaling and cerebellar gene networks in risk for bipolar disorder.
Mol Psychiatry
; 27(9): 3842-3856, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35546635
9.
Molecular Pharmacology and Neurobiology of Rapid-Acting Antidepressants.
Annu Rev Pharmacol Toxicol
; 59: 213-236, 2019 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30296896
10.
NMDAR inhibition-independent antidepressant actions of ketamine metabolites.
Nature
; 533(7604): 481-6, 2016 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27144355
11.
(2R,6R)-hydroxynorketamine exerts mGlu2 receptor-dependent antidepressant actions.
Proc Natl Acad Sci U S A
; 116(13): 6441-6450, 2019 03 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-30867285
12.
Antidepressant-relevant concentrations of the ketamine metabolite (2R,6R)-hydroxynorketamine do not block NMDA receptor function.
Proc Natl Acad Sci U S A
; 116(11): 5160-5169, 2019 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30796190
13.
Ketamine and the Future of Rapid-Acting Antidepressants.
Annu Rev Clin Psychol
; 17: 207-231, 2021 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33561364
14.
Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms.
Pharmacol Rev
; 70(3): 621-660, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29945898
15.
A Randomized Trial of the N-Methyl-d-Aspartate Receptor Glycine Site Antagonist Prodrug 4-Chlorokynurenine in Treatment-Resistant Depression.
Int J Neuropsychopharmacol
; 23(7): 417-425, 2020 07 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-32236521
16.
Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects.
Mol Psychiatry
; 24(7): 1040-1052, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29487402
17.
Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations.
Proc Natl Acad Sci U S A
; 113(47): E7580-E7589, 2016 11 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27834214
18.
Cigarette smoke and nicotine effects on brain proinflammatory responses and behavioral and motor function in HIV-1 transgenic rats.
J Neurovirol
; 24(2): 246-253, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29644536
19.
Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?
Int J Neuropsychopharmacol
; 21(8): 777-785, 2018 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29554264
20.
Zanos et al. reply.
Nature
; 546(7659): E4-E5, 2017 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640272