Detalhe da pesquisa
1.
BNT162b vaccines protect rhesus macaques from SARS-CoV-2.
Nature
; 592(7853): 283-289, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33524990
2.
Machine Learning for Prioritization of Thermostabilizing Mutations for G-Protein Coupled Receptors.
Biophys J
; 117(11): 2228-2239, 2019 12 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31703801
3.
Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.
J Biol Chem
; 287(44): 37321-9, 2012 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-22961980
4.
Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell line.
Protein Expr Purif
; 87(1): 27-34, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23069765
5.
Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat Struct Mol Biol
; 30(1): 22-30, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36522428
6.
Glycomimetic ligands for the human asialoglycoprotein receptor.
J Am Chem Soc
; 134(4): 1978-81, 2012 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22280495
7.
Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors.
Bioorg Med Chem Lett
; 22(24): 7523-9, 2012 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23153798
8.
Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia.
Nat Struct Mol Biol
; 14(5): 413-9, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17435765
9.
Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.
Nat Struct Mol Biol
; 14(2): 106-13, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17237796
10.
A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor.
J Med Chem
; 65(12): 8208-8226, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647711
11.
Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20.
Nat Commun
; 11(1): 3031, 2020 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32541785
12.
Demonstration of In Vitro to In Vivo Translation of a TYK2 Inhibitor That Shows Cross Species Potency Differences.
Sci Rep
; 10(1): 8974, 2020 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32488071
13.
Binding to the low-density lipoprotein receptor accelerates futile catalytic cycling in PCSK9 and raises the equilibrium level of intramolecular acylenzyme.
Biochemistry
; 48(13): 2941-9, 2009 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19222187
14.
Trifluoromethylpyrimidine-based inhibitors of proline-rich tyrosine kinase 2 (PYK2): structure-activity relationships and strategies for the elimination of reactive metabolite formation.
Bioorg Med Chem Lett
; 18(23): 6071-7, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18951788
15.
Crystal structures of interleukin 17A and its complex with IL-17 receptor A.
Nat Commun
; 4: 1888, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23695682
16.
Specificity determinants of human cathepsin s revealed by crystal structures of complexes.
Biochemistry
; 42(11): 3203-13, 2003 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-12641451