RESUMO
AIM: The aim of this study was to observe the findings of magnetic resonance spectroscopy of solitary thyroid nodules and its correlation with histopathology. MATERIALS AND METHODS: In this study, magnetic resonance spectroscopy was carried out on 26 patients having solitary thyroid nodules. Magnetic resonance spectroscopy (MRS) was performed on a 1.5T super conductive system with gradient strength of 33mTs. Fine needle aspiration cytology was done after MRS. All 26 patients underwent surgery either because of cytopathologically proven malignancy or because of cosmetic reasons. Findings of magnetic resonance spectroscopy were compared with histopathology of thyroid specimens. RESULTS AND CONCLUSION: It was seen that presence or absence of choline peak correlates very well with presence or absence of malignant foci with in the nodule (sensitivity=100%; specificity=88.88%). These results indicate that magnetic resonance spectroscopy may prove to be an useful diagnostic modality for carcinoma thyroid.
Assuntos
Carcinoma/diagnóstico , Espectroscopia de Ressonância Magnética , Neoplasias da Glândula Tireoide/diagnóstico , Nódulo da Glândula Tireoide/diagnóstico , Adenocarcinoma Folicular/diagnóstico , Adenocarcinoma Folicular/patologia , Adenocarcinoma Mucinoso/diagnóstico , Adenocarcinoma Mucinoso/patologia , Adenoma/diagnóstico , Adenoma/patologia , Adolescente , Adulto , Biópsia por Agulha Fina , Carcinoma/patologia , Carcinoma Papilar/diagnóstico , Carcinoma Papilar/patologia , Criança , Colina/análise , Cistos/diagnóstico , Cistos/patologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Sensibilidade e Especificidade , Doenças da Glândula Tireoide/diagnóstico , Doenças da Glândula Tireoide/patologia , Neoplasias da Glândula Tireoide/patologia , Nódulo da Glândula Tireoide/patologia , Tireoidite Autoimune/diagnóstico , Tireoidite Autoimune/patologiaAssuntos
Embolia Pulmonar/tratamento farmacológico , Ativador de Plasminogênio Tecidual/administração & dosagem , Idoso , Diagnóstico Diferencial , Ecocardiografia , Fibrinolíticos/administração & dosagem , Seguimentos , Humanos , Injeções Intravenosas , Masculino , Embolia Pulmonar/diagnóstico , Índice de Gravidade de Doença , Tenecteplase , Tomografia Computadorizada por Raios XRESUMO
Typhoid fever is associated with a wide spectrum of neurological complications. Acute transverse myelitis is a rare complication with only a few reports in adults and none in children. A 15-year-old boy with typhoid fever is reported who developed acute transverse myelitis in the 3rd week of illness. He was treated with antibiotics and corticosteroids and made a complete recovery.
Assuntos
Mielite Transversa/diagnóstico , Mielite Transversa/etiologia , Febre Tifoide/complicações , Febre Tifoide/diagnóstico , Adolescente , Corticosteroides/administração & dosagem , Antibacterianos/administração & dosagem , Humanos , Imunossupressores/administração & dosagem , Imageamento por Ressonância Magnética , Masculino , Mielite Transversa/tratamento farmacológico , Mielite Transversa/patologia , Radiografia , Coluna Vertebral/diagnóstico por imagem , Resultado do Tratamento , Febre Tifoide/tratamento farmacológico , Febre Tifoide/patologiaRESUMO
OBJECTIVES: Thyroid nodular swellings are very common, consisting of both benign and malignant ones. Fine needle aspiration cytology is an excellent diagnostic modality for papillary cancers, medullary cancers, colloid goiter and lymphoma but fails in differentiating follicular adenomas from carcinomas. The purpose of this study was to evaluate role of Dynamic MRI with signal intensity time curve evaluation in differentiating benign from malignant follicular nodules. MATERIALS AND METHODS: This study was carried out in Department of Surgery in collaboration with department of Radiodiagnosis, Maulana Azad Medical College, Delhi. 28 patients with solitary thyroid nodule (STN) having follicular etiologies were included in the study. Dynamic MRI with signal intensity time curve analysis was carried out in all the cases and findings were compared with the final diagnosis based on histopathological examination of surgical specimen. RESULTS: In the present study, rapid enhancement was seen in 87.5% of malignant cases and washout pattern was seen in 87.5% of malignant STN (p=0.019). Only 20% of the benign lesions showed washout pattern (p=0.0034). Benign cases demonstrated gradual enhancement in 85% cases as compared to 12.5% in malignant STN (p=0.0098). CONCLUSION: This study suggests that signal intensity time curve may help in differentiating benign from malignant follicular thyroid nodules.