Detalhe da pesquisa
1.
Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.
Nucleic Acids Res
; 51(9): 4341-4362, 2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36928661
2.
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.
Nucleic Acids Res
; 51(19): 10484-10505, 2023 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697435
3.
RIP3 mediates the embryonic lethality of caspase-8-deficient mice.
Nature
; 471(7338): 368-72, 2011 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-21368762
4.
DICER1/Alu RNA dysmetabolism induces Caspase-8-mediated cell death in age-related macular degeneration.
Proc Natl Acad Sci U S A
; 111(45): 16082-7, 2014 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25349431
5.
Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis.
PLoS Genet
; 9(1): e1003259, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23382699
6.
RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks.
Proc Natl Acad Sci U S A
; 110(52): 20982-7, 2013 Dec 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24324146
7.
The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival.
J Biol Chem
; 289(2): 1183-91, 2014 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-24275659
8.
The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets.
Diabetologia
; 57(4): 765-75, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24442508
9.
Caspase-8 is essential for maintaining chromosomal stability and suppressing B-cell lymphomagenesis.
Blood
; 119(15): 3495-502, 2012 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22343728
10.
Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer.
PLoS Genet
; 7(5): e1001385, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21625617
11.
Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome.
PLoS Genet
; 7(4): e1001381, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21552324
12.
Role of Pirh2 in mediating the regulation of p53 and c-Myc.
PLoS Genet
; 7(11): e1002360, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22125490
13.
SARS-CoV-2 targets ribosomal RNA biogenesis.
Cell Rep
; 43(3): 113891, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38427561
14.
DNA double-strand break-capturing nuclear envelope tubules drive DNA repair.
Nat Struct Mol Biol
; 2024 Apr 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38632359
15.
Dysregulation of the mevalonate pathway promotes transformation.
Proc Natl Acad Sci U S A
; 107(34): 15051-6, 2010 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20696928
16.
Dual Role of Caspase 8 in Adipocyte Apoptosis and Metabolic Inflammation.
Diabetes
; 72(12): 1751-1765, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37699387
17.
Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages.
Cell Rep
; 42(10): 113256, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37847590
18.
DNA-damage repair; the good, the bad, and the ugly.
EMBO J
; 27(4): 589-605, 2008 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-18285820
19.
Emerging roles of DNA topoisomerases in the regulation of R-loops.
Mutat Res Genet Toxicol Environ Mutagen
; 876-877: 503450, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35483781
20.
IPO11 regulates the nuclear import of BZW1/2 and is necessary for AML cells and stem cells.
Leukemia
; 36(5): 1283-1295, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35152270