Detalhe da pesquisa
1.
A high-resolution enhancer atlas of the developing telencephalon.
Cell
; 152(4): 895-908, 2013 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23375746
2.
Development and evolution of the human neocortex.
Cell
; 146(1): 18-36, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21729779
3.
Neutral or detrimental effects of TREM2 agonist antibodies in preclinical models of Alzheimer's Disease and Multiple Sclerosis.
J Neurosci
; 2024 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38830764
4.
Genome-Wide Analysis of Differential Gene Expression and Splicing in Excitatory Neurons and Interneuron Subtypes.
J Neurosci
; 40(5): 958-973, 2020 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31831521
5.
Trem2 Deletion Reduces Late-Stage Amyloid Plaque Accumulation, Elevates the Aß42:Aß40 Ratio, and Exacerbates Axonal Dystrophy and Dendritic Spine Loss in the PS2APP Alzheimer's Mouse Model.
J Neurosci
; 40(9): 1956-1974, 2020 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980586
6.
Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease.
PLoS Genet
; 14(11): e1007427, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388101
7.
Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury.
J Neurosci
; 36(38): 9962-75, 2016 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27656033
8.
Neurogenic radial glia in the outer subventricular zone of human neocortex.
Nature
; 464(7288): 554-561, 2010 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20154730
9.
Mouse Emi2 is required to enter meiosis II by reestablishing cyclin B1 during interkinesis.
J Cell Biol
; 174(6): 791-801, 2006 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-16966421
10.
TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease.
Cell Rep
; 37(13): 110158, 2021 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34965428
11.
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by ß-amyloid pathology.
Neuron
; 109(8): 1283-1301.e6, 2021 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33675684
12.
Alzheimer's Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation.
Cell Rep
; 31(13): 107843, 2020 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32610143
13.
Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy.
Cell Rep
; 28(8): 2111-2123.e6, 2019 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31433986
14.
Microglia in Alzheimer's disease.
J Cell Biol
; 217(2): 459-472, 2018 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29196460
15.
Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Cell Rep
; 22(3): 832-847, 2018 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29346778
16.
Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1.
Mol Biol Cell
; 15(12): 5623-34, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15469984
17.
TREM2, Microglia, and Neurodegenerative Diseases.
Trends Mol Med
; 23(6): 512-533, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28442216
18.
Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation.
J Exp Med
; 214(9): 2611-2628, 2017 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28778989
19.
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
J Alzheimers Dis
; 56(3): 1037-1054, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106546
20.
Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.
Nat Commun
; 7: 11295, 2016 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097852