Detalhe da pesquisa
1.
Carboplatin-induced upregulation of pan ß-tubulin and class III ß-tubulin is implicated in acquired resistance and cross-resistance of ovarian cancer.
Cell Mol Life Sci
; 80(10): 294, 2023 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37718345
2.
Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo.
Small
; 19(22): e2300767, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36843221
3.
Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97.
Int J Mol Sci
; 24(7)2023 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37047353
4.
Insertion of (Bioactive) Equatorial Ligands into Platinum(IV) Complexes.
Angew Chem Int Ed Engl
; 62(46): e202311468, 2023 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37703130
5.
Oral Anticancer Heterobimetallic PtIV -AuI Complexes Show High In Vivo Activity and Low Toxicity.
Angew Chem Int Ed Engl
; 62(10): e202217233, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36628505
6.
Copper-Catalyzed Glutathione Oxidation is Accelerated by the Anticancer Thiosemicarbazone Dp44mT and Further Boosted at Lower pH.
J Am Chem Soc
; 144(32): 14758-14768, 2022 08 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-35929814
7.
Metal- and metalloid-based compounds to target and reverse cancer multidrug resistance.
Drug Resist Updat
; 58: 100778, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34403910
8.
Metal Drugs and the Anticancer Immune Response.
Chem Rev
; 119(2): 1519-1624, 2019 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30489072
9.
Discrimination between 34 of 36 Possible Combinations of Three C>T SNP Genotypes in the MGMT Promoter by High Resolution Melting Analysis Coupled with Pyrosequencing Using A Single Primer Set.
Int J Mol Sci
; 22(22)2021 Nov 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34830407
10.
Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs.
Angew Chem Int Ed Engl
; 60(24): 13405-13413, 2021 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33755286
11.
Lipid droplet-mediated scavenging as novel intrinsic and adaptive resistance factor against the multikinase inhibitor ponatinib.
Int J Cancer
; 147(6): 1680-1693, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32064608
12.
The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects.
Chemistry
; 26(10): 2211-2221, 2020 Feb 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-31560142
13.
Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs.
Inorg Chem
; 59(23): 17794-17810, 2020 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33222438
14.
A-ring and E-ring modifications of the cytotoxic alkaloid Luotonin A: Synthesis, computational and biological studies.
Bioorg Med Chem
; 28(9): 115443, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32201190
15.
Development and biological investigations of hypoxia-sensitive prodrugs of the tyrosine kinase inhibitor crizotinib.
Bioorg Chem
; 99: 103778, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32229347
16.
Destabilization of FoxM1 and Inhibition of Topoisomerase I Contribute to Cytotoxicity of Prenylated Xanthones Isolated from Metaxya rostrata.
Planta Med
; 86(15): 1073-1079, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023632
17.
Reactive Oxygen Species (ROS)-Sensitive Prodrugs of the Tyrosine Kinase Inhibitor Crizotinib.
Molecules
; 25(5)2020 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32143435
18.
Methylated Xanthones from the Rootlets of Metaxya rostrata Display Cytotoxic Activity in Colorectal Cancer Cells.
Molecules
; 25(19)2020 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32998226
19.
Synthesis and Cytotoxicity of Water-Soluble Dual- and Triple-Action Satraplatin Derivatives: Replacement of Equatorial Chlorides of Satraplatin by Acetates.
Inorg Chem
; 58(24): 16676-16688, 2019 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31790216
20.
Synthesis, Characterization and inâ vitro Studies of a Cathepsin B-Cleavable Prodrug of the VEGFR Inhibitor Sunitinib.
Chem Biodivers
; 16(1): e1800520, 2019 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-30566287