Detalhe da pesquisa
1.
Comprehensive Transcriptomic Analysis of Novel Class I HDAC Proteolysis Targeting Chimeras (PROTACs).
Biochemistry
; 62(3): 645-656, 2023 02 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948047
2.
HDAC3 deacetylates the DNA mismatch repair factor MutSß to stimulate triplet repeat expansions.
Proc Natl Acad Sci U S A
; 117(38): 23597-23605, 2020 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32900932
3.
Bifunctional HDAC Therapeutics: One Drug to Rule Them All?
Molecules
; 25(19)2020 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987782
4.
Siderophore-Antibiotic Conjugate Design: New Drugs for Bad Bugs?
Molecules
; 24(18)2019 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31514464
5.
The design and synthesis of an antibacterial phenothiazine-siderophore conjugate.
Beilstein J Org Chem
; 14: 2646-2650, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30410626
6.
Synthesis and biological evaluation of 1,2-disubsubstituted 4-quinolone analogues of Pseudonocardia sp. natural products.
Beilstein J Org Chem
; 14: 2680-2688, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30410629
7.
Multifunctional supramolecular polymer networks as next-generation consolidants for archaeological wood conservation.
Proc Natl Acad Sci U S A
; 111(50): 17743-8, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25385610
8.
Divergent Synthesis of Quinolone Natural Products from Pseudonocardia sp. CL38489.
European J Org Chem
; 2016(35): 5799-5802, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28111524
9.
Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells.
Beilstein J Org Chem
; 12: 1428-33, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559393
10.
Diversity-oriented synthesis of macrocyclic peptidomimetics.
Proc Natl Acad Sci U S A
; 108(17): 6793-8, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383137
11.
Diversity-oriented synthesis of drug-like macrocyclic scaffolds using an orthogonal organo- and metal catalysis strategy.
Angew Chem Int Ed Engl
; 53(48): 13093-7, 2014 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25257387
12.
MDM2 Antagonist Idasanutlin Reduces HDAC1/2 Abundance and Corepressor Partners but Not HDAC3.
ACS Med Chem Lett
; 15(1): 93-98, 2024 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38229760
13.
Ligand binding kinetics of the quorum sensing regulator PqsR.
Biochemistry
; 52(25): 4433-8, 2013 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23713667
14.
Surface swarming motility by Pectobacterium atrosepticum is a latent phenotype that requires O antigen and is regulated by quorum sensing.
Microbiology (Reading)
; 159(Pt 11): 2375-2385, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24025601
15.
Design and synthesis of a biotinylated chemical probe for detecting the molecular targets of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin.
Molecules
; 18(10): 11783-96, 2013 Sep 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24071985
16.
Combating multidrug-resistant bacteria: current strategies for the discovery of novel antibacterials.
Angew Chem Int Ed Engl
; 52(41): 10706-33, 2013 Oct 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24038605
17.
PROTAC chemical probes for histone deacetylase enzymes.
RSC Chem Biol
; 4(9): 623-634, 2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37654508
18.
Design, synthesis and biological evaluation of non-natural modulators of quorum sensing in Pseudomonas aeruginosa.
Org Biomol Chem
; 10(30): 6032-44, 2012 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22499353
19.
Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics.
Org Biomol Chem
; 10(42): 8452-64, 2012 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-23014532
20.
A 'click' chemistry approach to novel entinostat (MS-275) based class I histone deacetylase proteolysis targeting chimeras.
RSC Med Chem
; 13(12): 1634-1639, 2022 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36545434