Detalhe da pesquisa
1.
Microglia regulate central nervous system myelin growth and integrity.
Nature
; 613(7942): 120-129, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36517604
2.
Inhibiting CSF1R alleviates cerebrovascular white matter disease and cognitive impairment.
Glia
; 72(2): 375-395, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-37909242
3.
4-Sodium phenyl butyric acid has both efficacy and counter-indicative effects in the treatment of Col4a1 disease.
Hum Mol Genet
; 28(4): 628-638, 2019 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30351356
4.
Deficiency of Nrf2 exacerbates white matter damage and microglia/macrophage levels in a mouse model of vascular cognitive impairment.
J Neuroinflammation
; 17(1): 367, 2020 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33261626
5.
Minocycline reduces microgliosis and improves subcortical white matter function in a model of cerebral vascular disease.
Glia
; 66(1): 34-46, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28722234
6.
White matter degeneration in vascular and other ageing-related dementias.
J Neurochem
; 144(5): 617-633, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29210074
7.
Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology.
Clin Sci (Lond)
; 132(8): 851-868, 2018 04 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29712883
8.
Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion.
J Neuroinflammation
; 14(1): 81, 2017 04 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28399892
9.
Chronic cerebral hypoperfusion alters amyloid-ß peptide pools leading to cerebral amyloid angiopathy, microinfarcts and haemorrhages in Tg-SwDI mice.
Clin Sci (Lond)
; 131(16): 2109-2123, 2017 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28667120
10.
Chronic cerebral hypoperfusion: a key mechanism leading to vascular cognitive impairment and dementia. Closing the translational gap between rodent models and human vascular cognitive impairment and dementia.
Clin Sci (Lond)
; 131(19): 2451-2468, 2017 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28963120
11.
Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia.
Brain
; 139(Pt 1): 242-58, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26667280
12.
Hippocampal capillary pericytes in post-stroke and vascular dementias and Alzheimer's disease and experimental chronic cerebral hypoperfusion.
Acta Neuropathol Commun
; 12(1): 29, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38360798
13.
ApoE isoform-specific regulation of regeneration in the peripheral nervous system.
Hum Mol Genet
; 20(12): 2406-21, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21478199
14.
A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases.
Stem Cell Reports
; 18(12): 2386-2399, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37977146
15.
Rapid disruption of axon-glial integrity in response to mild cerebral hypoperfusion.
J Neurosci
; 31(49): 18185-94, 2011 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22159130
16.
Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses.
Nat Neurosci
; 11(4): 476-87, 2008 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-18344994
17.
Nox2 underpins microvascular inflammation and vascular contributions to cognitive decline.
J Cereb Blood Flow Metab
; 42(7): 1176-1191, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35102790
18.
Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke.
Brain Pathol
; 32(6): e13101, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35748290
19.
Axon-glial disruption: the link between vascular disease and Alzheimer's disease?
Biochem Soc Trans
; 39(4): 881-5, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21787317
20.
Small vessels, dementia and chronic diseases-molecular mechanisms and pathophysiology.
Clin Sci (Lond)
; 130(21): 1875-9, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27660310