Detalhe da pesquisa
1.
Semaglutide in Patients with Obesity-Related Heart Failure and Type 2 Diabetes.
N Engl J Med
; 390(15): 1394-1407, 2024 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38587233
2.
Using genetic association data to guide drug discovery and development: Review of methods and applications.
Am J Hum Genet
; 110(2): 195-214, 2023 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36736292
3.
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.
N Engl J Med
; 389(24): 2221-2232, 2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37952131
4.
Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity.
N Engl J Med
; 389(12): 1069-1084, 2023 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37622681
5.
Semaglutide versus placebo in people with obesity-related heart failure with preserved ejection fraction: a pooled analysis of the STEP-HFpEF and STEP-HFpEF DM randomised trials.
Lancet
; 403(10437): 1635-1648, 2024 Apr 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38599221
6.
Unexpected gaps in knowledge of familial hypercholesterolaemia among Dutch general practitioners.
Neth Heart J
; 32(5): 213-220, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38573436
7.
Angiopoietin-like 3 inhibition and the liver: less is more?
Curr Opin Lipidol
; 34(6): 267-271, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37820081
8.
Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study.
Lancet
; 399(10326): 719-728, 2022 02 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35101175
9.
Evolocumab in Pediatric Heterozygous Familial Hypercholesterolemia.
N Engl J Med
; 383(14): 1317-1327, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32865373
10.
Evinacumab for Homozygous Familial Hypercholesterolemia.
N Engl J Med
; 383(8): 711-720, 2020 08 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32813947
11.
Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk: a Mendelian randomization study.
BMC Med
; 21(1): 158, 2023 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37101178
12.
Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: Design and baseline characteristics of SOUL, a randomized trial.
Diabetes Obes Metab
; 25(7): 1932-1941, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36945734
13.
LDL-C calculated by Friedewald, Martin-Hopkins, or NIH equation 2 versus beta-quantification: pooled alirocumab trials.
J Lipid Res
; 63(1): 100148, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34774485
14.
IL-6 inhibition with ziltivekimab in patients at high atherosclerotic risk (RESCUE): a double-blind, randomised, placebo-controlled, phase 2 trial.
Lancet
; 397(10289): 2060-2069, 2021 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015342
15.
Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.
BMC Med
; 20(1): 245, 2022 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35948913
16.
Dissecting the IL-6 pathway in cardiometabolic disease: A Mendelian randomization study on both IL6 and IL6R.
Br J Clin Pharmacol
; 88(6): 2875-2884, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34931349
17.
ANGPTL3 Inhibition With Evinacumab Results in Faster Clearance of IDL and LDL apoB in Patients With Homozygous Familial Hypercholesterolemia-Brief Report.
Arterioscler Thromb Vasc Biol
; 41(5): 1753-1759, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33691480
18.
Novel PCSK9 (Proprotein Convertase Subtilisin Kexin Type 9) Variants in Patients With Familial Hypercholesterolemia From Cape Town.
Arterioscler Thromb Vasc Biol
; 41(2): 934-943, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33147992
19.
The iterative lipid impact on inflammation in atherosclerosis.
Curr Opin Lipidol
; 32(5): 286-292, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34392272
20.
The clinical applicability of polygenic risk scores for LDL-cholesterol: considerations, current evidence and future perspectives.
Curr Opin Lipidol
; 32(2): 112-116, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33560669