Detalhe da pesquisa
1.
Computational drug discovery for castration-resistant prostate cancers through in vitro drug response modeling.
Proc Natl Acad Sci U S A
; 120(17): e2218522120, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37068243
2.
Sex-related differences in delayed doxorubicin-induced cardiac dysfunction in C57BL/6 mice.
Arch Toxicol
; 98(4): 1191-1208, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38244039
3.
Long non-coding RNA transcriptome of uncharacterized samples can be accurately imputed using protein-coding genes.
Brief Bioinform
; 21(2): 637-648, 2020 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657858
4.
Discovering long noncoding RNA predictors of anticancer drug sensitivity beyond protein-coding genes.
Proc Natl Acad Sci U S A
; 116(44): 22020-22029, 2019 10 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548386
5.
iMIRAGE: an R package to impute microRNA expression using protein-coding genes.
Bioinformatics
; 36(8): 2608-2610, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31860075
6.
Long Non-Coding RNA ANRIL as a Potential Biomarker of Chemosensitivity and Clinical Outcomes in Osteosarcoma.
Int J Mol Sci
; 22(20)2021 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34681828
7.
Discovering novel pharmacogenomic biomarkers by imputing drug response in cancer patients from large genomics studies.
Genome Res
; 27(10): 1743-1751, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28847918
8.
Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
Breast Cancer Res Treat
; 181(3): 623-633, 2020 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-32378051
9.
Artificial intelligence for drug response prediction in disease models.
Brief Bioinform
; 23(1)2022 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34655289
10.
Consistency in large pharmacogenomic studies.
Nature
; 540(7631): E1-E2, 2016 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-27905415
11.
Poly-omic prediction of complex traits: OmicKriging.
Genet Epidemiol
; 38(5): 402-15, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24799323
12.
Genetic architecture of microRNA expression: implications for the transcriptome and complex traits.
Am J Hum Genet
; 90(6): 1046-63, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22658545
13.
Genome-wide interrogation of longitudinal FEV1 in children with asthma.
Am J Respir Crit Care Med
; 190(6): 619-27, 2014 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25221879
14.
Mixed effects modeling of proliferation rates in cell-based models: consequence for pharmacogenomics and cancer.
PLoS Genet
; 8(2): e1002525, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-22346769
15.
Pharmacogenomics of EGFR-targeted therapies in non-small cell lung cancer: EGFR and beyond.
Chin J Cancer
; 34(4): 149-60, 2015 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25962919
16.
The impact of microRNA expression on cellular proliferation.
Hum Genet
; 133(7): 931-8, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24609542
17.
A review of computational methods for predicting cancer drug response at the single-cell level through integration with bulk RNAseq data.
Curr Opin Struct Biol
; 84: 102745, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38109840
18.
Integration of pan-cancer cell line and single-cell transcriptomic profiles enables inference of therapeutic vulnerabilities in heterogeneous tumors.
Cancer Res
; 2024 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38581448
19.
Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma.
Cancers (Basel)
; 16(9)2024 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38730673
20.
Computational Modeling to Identify Drugs Targeting Metastatic Castration-Resistant Prostate Cancer Characterized by Heightened Glycolysis.
Pharmaceuticals (Basel)
; 17(5)2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794139