Detalhe da pesquisa
1.
Endostatin lowers blood pressure via nitric oxide and prevents hypertension associated with VEGF inhibition.
Proc Natl Acad Sci U S A
; 109(28): 11306-11, 2012 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22733742
2.
Angiostatin regulates the expression of antiangiogenic and proapoptotic pathways via targeted inhibition of mitochondrial proteins.
Blood
; 114(9): 1987-98, 2009 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19465692
3.
Linking antibody Fc domain to endostatin significantly improves endostatin half-life and efficacy.
Clin Cancer Res
; 14(5): 1487-93, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18316573
4.
A 27-amino-acid synthetic peptide corresponding to the NH2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity.
Cancer Res
; 65(9): 3656-63, 2005 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15867360
5.
Binding of endostatin to endothelial heparan sulphate shows a differential requirement for specific sulphates.
Biochem J
; 375(Pt 1): 131-9, 2003 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12812520
6.
Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis.
J Ophthalmol
; 2015: 137136, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26491546
7.
Angiostatin inhibits and regresses corneal neovascularization.
Arch Ophthalmol
; 120(8): 1063-8, 2002 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12149060
8.
Two Endogenous Antiangiogenic Inhibitors, Endostatin and Angiostatin, Demonstrate Biphasic Curves in their Antitumor Profiles.
Dose Response
; 9(3): 369-76, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-22013399
9.
Improvement in the standard treatment for experimental glioma by fusing antibody Fc domain to endostatin.
J Neurosurg
; 115(6): 1139-46, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21923243
10.
HSPG-binding peptide corresponding to the exon 6a-encoded domain of VEGF inhibits tumor growth by blocking angiogenesis in murine model.
PLoS One
; 5(4): e9945, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20376344
11.
Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model.
Fertil Steril
; 85(1): 71-7, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16412733
12.
The morphogenic properties of oligomeric endostatin are dependent on cell surface heparan sulfate.
J Biol Chem
; 281(21): 14813-22, 2006 May 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16481316
13.
Endostatin binds biglycan and LDL and interferes with LDL retention to the subendothelial matrix during atherosclerosis.
J Lipid Res
; 46(9): 1849-59, 2005 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-15995169
14.
Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis.
Proc Natl Acad Sci U S A
; 100(8): 4736-41, 2003 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12682294
15.
Laminin modulates morphogenic properties of the collagen XVIII endostatin domain.
J Biol Chem
; 277(47): 45211-8, 2002 Nov 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-12237301