Detalhe da pesquisa
1.
PTK2 regulates tau-induced neurotoxicity via phosphorylation of p62 at Ser403.
J Neurogenet
; 37(1-2): 10-19, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36000467
2.
Interrogation of kinase genetic interactions provides a global view of PAK1-mediated signal transduction pathways.
J Biol Chem
; 295(50): 16906-16919, 2020 12 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33060198
3.
Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target.
Genome Res
; 27(9): 1487-1500, 2017 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28596290
4.
The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response.
J Neuroinflammation
; 17(1): 299, 2020 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33054766
5.
Inhibition of MEK5 suppresses TDP-43 toxicity via the mTOR-independent activation of the autophagy-lysosome pathway.
Biochem Biophys Res Commun
; 513(4): 925-932, 2019 06 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31005259
6.
Dietary Restriction and Neuroinflammation: A Potential Mechanistic Link.
Int J Mol Sci
; 20(3)2019 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-30678217
7.
Astrocytic Orosomucoid-2 Modulates Microglial Activation and Neuroinflammation.
J Neurosci
; 37(11): 2878-2894, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193696
8.
Interaction between optineurin and Rab1a regulates autophagosome formation in neuroblastoma cells.
J Neurosci Res
; 96(3): 407-415, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28843006
9.
Therapeutic modulation of GSTO activity rescues FUS-associated neurotoxicity via deglutathionylation in ALS disease models.
Dev Cell
; 57(6): 783-798.e8, 2022 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35320731
10.
Overexpression of SIRT3 Suppresses Oxidative Stress-induced Neurotoxicity and Mitochondrial Dysfunction in Dopaminergic Neuronal Cells.
Exp Neurobiol
; 30(5): 341-355, 2021 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34737239
11.
Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation.
Cells
; 10(3)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803845
12.
Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction.
Antioxidants (Basel)
; 11(1)2021 Dec 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35052586
13.
HEXA-018, a Novel Inducer of Autophagy, Rescues TDP-43 Toxicity in Neuronal Cells.
Front Pharmacol
; 12: 747975, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34925009
14.
The Role of Glial Mitochondria in α-Synuclein Toxicity.
Front Cell Dev Biol
; 8: 548283, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33262983
15.
The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies.
Exp Mol Med
; 52(10): 1652-1662, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33051572
16.
The Role of HDAC6 in TDP-43-Induced Neurotoxicity and UPS Impairment.
Front Cell Dev Biol
; 8: 581942, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33282865
17.
Yeast-Based Genetic Interaction Analysis of Human Kinome.
Cells
; 9(5)2020 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32392905
18.
PTK2/FAK regulates UPS impairment via SQSTM1/p62 phosphorylation in TARDBP/TDP-43 proteinopathies.
Autophagy
; 16(8): 1396-1412, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31690171
19.
Microglia-Astrocyte Crosstalk: An Intimate Molecular Conversation.
Neuroscientist
; 25(3): 227-240, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29931997
20.
A novel small-molecule agonist of PPAR-γ potentiates an anti-inflammatory M2 glial phenotype.
Neuropharmacology
; 109: 159-169, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27288982