Detalhe da pesquisa
1.
Replacement of the hydroxamic acid group in the selective HDAC8 inhibitor PCI-34051.
Bioorg Med Chem Lett
; 108: 129810, 2024 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38782078
2.
Phenotypic characterization of the Hordeum bulbosum derived leaf rust resistance genes Rph22 and Rph26 in barley.
J Appl Microbiol
; 133(3): 2083-2094, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35815837
3.
Selecting a minimal set of androgen receptor assays for screening chemicals.
Regul Toxicol Pharmacol
; 117: 104764, 2020 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798611
4.
Genetic mapping of a barley leaf rust resistance gene Rph26 introgressed from Hordeum bulbosum.
Theor Appl Genet
; 131(12): 2567-2580, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30178277
5.
The production of 3D tumor spheroids for cancer drug discovery.
Drug Discov Today Technol
; 23: 27-36, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-28647083
6.
Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors.
Bioorg Med Chem Lett
; 26(15): 3581-5, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381083
7.
Marker assisted separation of resistance genes Rph22 and Rym16 (Hb) from an associated yield penalty in a barley: Hordeum bulbosum introgression line.
Theor Appl Genet
; 128(6): 1137-49, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25800008
8.
Synthesis and biological evaluation of 3-aminoisoquinolin-1(2H)-one based inhibitors of the dual-specificity phosphatase Cdc25B.
Bioorg Med Chem
; 23(12): 2810-8, 2015 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25703307
9.
2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway.
Bioorg Med Chem Lett
; 24(21): 5081-5, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25288188
10.
Use of an electronic alert to identify patients with acute kidney injury.
Clin Med (Lond)
; 14(1): 22-6, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24532738
11.
Subcutaneous administration of a novel TRPM8 antagonist reverses cold hypersensitivity while attenuating the drop in core body temperature.
Br J Pharmacol
; 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794851
12.
Rph22: mapping of a novel leaf rust resistance gene introgressed from the non-host Hordeum bulbosum L. into cultivated barley (Hordeum vulgare L.).
Theor Appl Genet
; 126(6): 1613-25, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23467993
13.
Characterization of allosteric modulators that disrupt androgen receptor co-activator protein-protein interactions to alter transactivation-Drug leads for metastatic castration resistant prostate cancer.
SLAS Discov
; 2023 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37549772
14.
Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines.
SLAS Discov
; 27(1): 39-54, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35058175
15.
Validation of HDAC8 Inhibitors as Drug Discovery Starting Points to Treat Acute Kidney Injury.
ACS Pharmacol Transl Sci
; 5(4): 207-215, 2022 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35434532
16.
Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines.
SLAS Discov
; 26(5): 712-729, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208016
17.
Three dimensional engineered models to study hypoxia biology in breast cancer.
Cancer Lett
; 490: 124-142, 2020 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32569616
18.
Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines.
SLAS Discov
; 25(4): 329-349, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31983262
19.
Patient-derived tumor organoid predicts drugs response in glioblastoma: A step forward in personalized cancer therapy?
J Clin Neurosci
; 78: 400-402, 2020 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-32340843
20.
Marker development and characterisation of Hordeum bulbosum introgression lines: a resource for barley improvement.
Theor Appl Genet
; 118(8): 1429-37, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19263032