Detalhe da pesquisa
1.
Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon.
Antimicrob Agents Chemother
; 63(2)2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30455233
2.
Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial.
PLoS Med
; 13(1): e1001938, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26757276
3.
Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites.
Hum Mol Genet
; 21(5): 1145-54, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22108178
4.
Intraperitoneal chemotherapy of peritoneal carcinomatosis using pressurized aerosol as an alternative to liquid solution: first evidence for efficacy.
Ann Surg Oncol
; 21(2): 553-9, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24006094
5.
LC-MS/MS method for the simultaneous quantification of artesunate and its metabolites dihydroartemisinin and dihydroartemisinin glucuronide in human plasma.
Anal Bioanal Chem
; 406(17): 4299-308, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24760398
6.
A new [2H]-labelled α-trichloroimidate glucuronic ester for the synthesis of deuterated drug conjugates.
J Labelled Comp Radiopharm
; 57(12): 699-703, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25339577
7.
Functional characterization of protein variants of the human multidrug transporter ABCC2 by a novel targeted expression system in fibrosarcoma cells.
Hum Mutat
; 33(4): 750-62, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22290738
8.
Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone.
Pharmaceutics
; 14(8)2022 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015360
9.
Prediction of Drug-Drug-Gene Interaction Scenarios of (E)-Clomiphene and Its Metabolites Using Physiologically Based Pharmacokinetic Modeling.
Pharmaceutics
; 14(12)2022 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36559098
10.
Quantification of clomiphene metabolite isomers in human plasma by rapid-resolution liquid chromatography-electrospray ionization-tandem mass spectrometry.
Anal Bioanal Chem
; 400(10): 3429-41, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21533795
11.
Stereoselective quantification of phase 1 and 2 metabolites of clomiphene in human plasma and urine.
Talanta
; 221: 121658, 2021 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33076169
12.
Data-driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment.
CPT Pharmacometrics Syst Pharmacol
; 10(7): 782-793, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34053199
13.
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.
Hepatology
; 50(4): 1227-40, 2009 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-19591196
14.
Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans.
Front Genet
; 11: 944, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32973880
15.
Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1.
N Engl J Med
; 348(15): 1442-8, 2003 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12686700
16.
Translational learning from clinical studies predicts drug pharmacokinetics across patient populations.
NPJ Syst Biol Appl
; 3: 11, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28649438
17.
Implications of genetic polymorphisms in drug transporters for pharmacotherapy.
Cancer Lett
; 234(1): 4-33, 2006 Mar 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16504381
18.
Neonatal jaundice and bilirubin UDP-glucuronosyl transferase 1A1 gene polymorphism in Turkish patients.
Basic Clin Pharmacol Toxicol
; 98(4): 377-80, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16623861
19.
Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other membrane transporters.
Genome Med
; 8(1): 119, 2016 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27825374
20.
Association of the ABCB1 3435C>T polymorphism with antiemetic efficacy of 5-hydroxytryptamine type 3 antagonists.
Clin Pharmacol Ther
; 78(6): 619-26, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16338277