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1.
Molecules ; 29(8)2024 Apr 16.
Artigo em Inglês | MEDLINE | ID: mdl-38675617

RESUMO

Nanoemulsions are gaining interest in a variety of products as a means of integrating easily degradable bioactive compounds, preserving them from oxidation, and increasing their bioavailability. However, preparing stable emulsion compositions with the desired characteristics is a difficult task. The aim of this study was to encapsulate the Tinospora cordifolia aqueous extract (TCAE) into a water in oil (W/O) nanoemulsion and identify its critical process and formulation variables, like oil (27-29.4 mL), the surfactant concentration (0.6-3 mL), and sonication amplitude (40% to 100%), using response surface methodology (RSM). The responses of this formulation were studied with an analysis of the particle size (PS), free fatty acids (FFAs), and encapsulation efficiency (EE). In between, we have studied a fishbone diagram that was used to measure risk and preliminary research. The optimized condition for the formation of a stable nanoemulsion using quality by design was surfactant (2.43 mL), oil concentration (27.61 mL), and sonication amplitude (88.6%), providing a PS of 171.62 nm, FFA content of 0.86 meq/kg oil and viscosity of 0.597 Pa.s for the blank sample compared to the enriched TCAE nanoemulsion with a PS of 243.60 nm, FFA content of 0.27 meq/kg oil and viscosity of 0.22 Pa.s. The EE increases with increasing concentrations of TCAE, from 56.88% to 85.45%. The RSM response demonstrated that both composition variables had a considerable impact on the properties of the W/O nanoemulsion. Furthermore, after the storage time, the enriched TCAE nanoemulsion showed better stability over the blank nanoemulsion, specially the FFAs, and the blank increased from 0.142 to 1.22 meq/kg oil, while TCAE showed 0.266 to 0.82 meq/kg.


Assuntos
Emulsões , Tamanho da Partícula , Extratos Vegetais , Tinospora , Água , Emulsões/química , Extratos Vegetais/química , Tinospora/química , Água/química , Sonicação , Nanopartículas/química , Óleos/química , Tensoativos/química
2.
Mol Biol Rep ; 50(12): 10351-10364, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37817020

RESUMO

This review presents an overview of one of the effective strategies for improving the anticancer impact of many drugs including sorafenib using a drug delivery system by employing nanoparticles that is produced through a biological system. The biological process has a lot of benefits, including being inexpensive and safe for the environment. Sorafenib is one of a multi-kinase inhibitor that inhibits molecularly targeted kinases. Because of its poor pharmacokinetic characteristics, such as fast elimination and limited water solubility, the bioavailability of Sorafenib is extremely low. More intelligent nano formulations of sorafenib have been developed to boost both the drug's target ability and bioavailability. Researchers in a wide variety of sectors, including nanomedicine, have recently been interested in the topic of nanotechnology. It is possible for the body to develop resistance to widely used drugs available for treatment of liver cancer, including sorafenib. As a result, our goal of this research is to highlight the efficacy of nanomedicine-based drug delivery system to enhance drug's cancer-fighting properties. Because of their magnetic properties, certain nanoparticle materials can be employed as a carrier for the medicine to the exact place where the cancer is located. This can lower the amount of the drug that is administered with no impact on the normal cells.


Assuntos
Antineoplásicos , Carcinoma Hepatocelular , Neoplasias Hepáticas , Nanopartículas , Humanos , Carcinoma Hepatocelular/tratamento farmacológico , Carcinoma Hepatocelular/patologia , Sorafenibe/uso terapêutico , Neoplasias Hepáticas/tratamento farmacológico , Neoplasias Hepáticas/patologia , Sistemas de Liberação de Fármacos por Nanopartículas , Antineoplásicos/uso terapêutico , Sistemas de Liberação de Medicamentos
3.
Sensors (Basel) ; 23(13)2023 Jun 24.
Artigo em Inglês | MEDLINE | ID: mdl-37447712

RESUMO

BACKGROUND: In our current digital world, smartphones are no longer limited to communication but are used in various real-world applications. In the healthcare industry, smartphones have sensors that can record data about our daily activities. Such data can be used for many healthcare purposes, such as elderly healthcare services, early disease diagnoses, and archiving patient data for further use. However, the data collected from the various sensors involve high dimensional features, which are not equally helpful in human activity recognition (HAR). METHODS: This paper proposes an algorithm for selecting the most relevant subset of features that will contribute efficiently to the HAR process. The proposed method is based on a hybrid version of the recent Coronavirus Disease Optimization Algorithm (COVIDOA) with Simulated Annealing (SA). SA algorithm is merged with COVIDOA to improve its performance and help escape the local optima problem. RESULTS: The UCI-HAR dataset from the UCI machine learning repository assesses the proposed algorithm's performance. A comparison is conducted with seven well-known feature selection algorithms, including the Arithmetic Optimization Algorithm (AOA), Gray Wolf Optimizer (GWO), Whale Optimization Algorithm (WOA), Reptile Search Algorithm (RSA), Zebra Optimization Algorithm (ZOA), Gradient-Based Optimizer (GBO), Seagull Optimization Algorithm (SOA), and Coyote Optimization Algorithm (COA) regarding fitness, STD, accuracy, size of selected subset, and processing time. CONCLUSIONS: The results proved that the proposed approach outperforms state-of-the-art HAR techniques, achieving an average performance of 97.82% in accuracy and a reduction ratio in feature selection of 52.7%.


Assuntos
Infecções por Coronavirus , Coronavirus , Idoso , Humanos , Infecções por Coronavirus/diagnóstico , Algoritmos , Atividades Humanas , Internet
4.
Sensors (Basel) ; 23(15)2023 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-37571793

RESUMO

Artificial intelligence (AI) systems are increasingly used in corporate security measures to predict the status of assets and suggest appropriate procedures. These programs are also designed to reduce repair time. One way to create an efficient system is to integrate physical repair agents with a computerized management system to develop an intelligent system. To address this, there is a need for a new technique to assist operators in interacting with a predictive system using natural language. The system also uses double neural network convolutional models to analyze device data. For fault prioritization, a technique utilizing fuzzy logic is presented. This strategy ranks the flaws based on the harm or expense they produce. However, the method's success relies on ongoing improvement in spoken language comprehension through language modification and query processing. To carry out this technique, a conversation-driven design is necessary. This type of learning relies on actual experiences with the assistants to provide efficient learning data for language and interaction models. These models can be trained to have more natural conversations. To improve accuracy, academics should construct and maintain publicly usable training sets to update word vectors. We proposed the model dataset (DS) with the Adam (AD) optimizer, Ridge Regression (RR) and Feature Mapping (FP). Our proposed algorithm has been coined with an appropriate acronym DSADRRFP. The same proposed approach aims to leverage each component's benefits to enhance the predictive model's overall performance and precision. This ensures the model is up-to-date and accurate. In conclusion, an AI system integrated with physical repair agents is a useful tool in corporate security measures. However, it needs to be refined to extract data from the operating system and to interact with users in a natural language. The system also needs to be constantly updated to improve accuracy.

5.
Sensors (Basel) ; 22(15)2022 Jul 27.
Artigo em Inglês | MEDLINE | ID: mdl-35957177

RESUMO

Copyright protection of medical images is a vital goal in the era of smart healthcare systems. In recent telemedicine applications, medical images are sensed using medical imaging devices and transmitted to remote places for screening by physicians and specialists. During their transmission, the medical images could be tampered with by intruders. Traditional watermarking methods embed the information in the host images to protect the copyright of medical images. The embedding destroys the original image and cannot be applied efficiently to images used in medicine that require high integrity. Robust zero-watermarking methods are preferable over other watermarking algorithms in medical image security due to their outstanding performance. Most existing methods are presented based on moments and moment invariants, which have become a prominent method for zero-watermarking due to their favorable image description capabilities and geometric invariance. Although moment-based zero-watermarking can be an effective approach to image copyright protection, several present approaches cannot effectively resist geometric attacks, and others have a low resistance to large-scale attacks. Besides these issues, most of these algorithms rely on traditional moment computation, which suffers from numerical error accumulation, leading to numerical instabilities, and time consumption and affecting the performance of these moment-based zero-watermarking techniques. In this paper, we derived multi-channel Gaussian-Hermite moments of fractional-order (MFrGHMs) to solve the problems. Then we used a kernel-based method for the highly accurate computation of MFrGHMs to solve the computation issue. Then, we constructed image features that are accurate and robust. Finally, we presented a new zero-watermarking scheme for color medical images using accurate MFrGHMs and 1D Chebyshev chaotic features to achieve lossless copyright protection of the color medical images. We performed experiments where their outcomes ensure the robustness of the proposed zero-watermarking algorithms against various attacks. The proposed zero-watermarking algorithm achieves a good balance between robustness and imperceptibility. Compared with similar existing algorithms, the proposed algorithm has superior robustness, security, and time computation.


Assuntos
Algoritmos , Segurança Computacional , Direitos Autorais , Distribuição Normal
7.
PeerJ Comput Sci ; 10: e2028, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38855210

RESUMO

The graphical user interface (GUI) in mobile applications plays a crucial role in connecting users with mobile applications. GUIs often receive many UI design smells, bugs, or feature enhancement requests. The design smells include text overlap, component occlusion, blur screens, null values, and missing images. It also provides for the behavior of mobile applications during their usage. Manual testing of mobile applications (app as short in the rest of the document) is essential to ensuring app quality, especially for identifying usability and accessibility that may be missed during automated testing. However, it is time-consuming and inefficient due to the need for testers to perform actions repeatedly and the possibility of missing some functionalities. Although several approaches have been proposed, they require significant performance improvement. In addition, the key challenges of these approaches are incorporating the design guidelines and rules necessary to follow during app development and combine the syntactical and semantic information available on the development forums. In this study, we proposed a UI bug identification and localization approach called Mobile-UI-Repair (M-UI-R). M-UI-R is capable of recognizing graphical user interfaces (GUIs) display issues and accurately identifying the specific location of the bug within the GUI. M-UI-R is trained and tested on the history data and also validated on real-time data. The evaluation shows that the average precision is 87.7% and the average recall is 86.5% achieved in the detection of UI display issues. M-UI-R also achieved an average precision of 71.5% and an average recall of 70.7% in the localization of UI design smell. Moreover, a survey involving eight developers demonstrates that the proposed approach provides valuable support for enhancing the user interface of mobile applications. This aids developers in their efforts to fix bugs.

8.
Sci Rep ; 14(1): 15538, 2024 Jul 05.
Artigo em Inglês | MEDLINE | ID: mdl-38969729

RESUMO

Drug delivery is the process or method of delivering a pharmacological product to have therapeutic effects on humans or animals. The use of nanoparticles to deliver medications to cells is driving the present surge in interest in improving human health. Green nanodrug delivery methods are based on chemical processes that are acceptable for the environment or that use natural biomaterials such as plant extracts and microorganisms. In this study, zinc oxide-superparamagnetic iron oxide-silver nanocomposite was synthesized via green synthesis method using Fusarium oxysporum fungi mycelia then loaded with sorafenib drug. The synthesized nanocomposites were characterized by UV-visibile spectroscopy, FTIR, TEM and SEM techniques. Sorafenib is a cancer treatment and is also known by its brand name, Nexavar. Sorafenib is the only systemic medication available in the world to treat hepatocellular carcinoma. Sorafenib, like many other chemotherapeutics, has side effects that restrict its effectiveness, including toxicity, nausea, mucositis, hypertension, alopecia, and hand-foot skin reaction. In our study, 40 male albino rats were given a single dose of diethyl nitrosamine (DEN) 60 mg/kg b.wt., followed by carbon tetrachloride 2 ml/kg b.wt. twice a week for one month. The aim of our study is using the zinc oxide-superparamagnetic iron oxide-silver nanocomposite that was synthesized by Fusarium oxysporum fungi mycelia as nanocarrier for enhancement the sorafenib anticancer effect.


Assuntos
Antineoplásicos , Carcinoma Hepatocelular , Neoplasias Hepáticas , Prata , Sorafenibe , Óxido de Zinco , Animais , Sorafenibe/farmacologia , Sorafenibe/química , Sorafenibe/administração & dosagem , Óxido de Zinco/química , Óxido de Zinco/farmacologia , Prata/química , Ratos , Antineoplásicos/farmacologia , Antineoplásicos/química , Antineoplásicos/administração & dosagem , Carcinoma Hepatocelular/tratamento farmacológico , Carcinoma Hepatocelular/patologia , Masculino , Neoplasias Hepáticas/tratamento farmacológico , Neoplasias Hepáticas/patologia , Portadores de Fármacos/química , Fusarium/efeitos dos fármacos , Nanopartículas de Magnetita/química , Nanocompostos/química , Humanos , Nanopartículas Magnéticas de Óxido de Ferro/química
9.
PeerJ ; 12: e17589, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38993977

RESUMO

Nanobiocatalysts (NBCs), which merge enzymes with nanomaterials, provide a potent method for improving enzyme durability, efficiency, and recyclability. This review highlights the use of eco-friendly synthesis methods to create sustainable nanomaterials for enzyme transport. We investigate different methods of immobilization, such as adsorption, ionic and covalent bonding, entrapment, and cross-linking, examining their pros and cons. The decreased environmental impact of green-synthesized nanomaterials from plants, bacteria, and fungi is emphasized. The review exhibits the various uses of NBCs in food industry, biofuel production, and bioremediation, showing how they can enhance effectiveness and eco-friendliness. Furthermore, we explore the potential impact of NBCs in biomedicine. In general, green nanobiocatalysts are a notable progression in enzyme technology, leading to environmentally-friendly and effective biocatalytic methods that have important impacts on industrial and biomedical fields.


Assuntos
Biocatálise , Enzimas Imobilizadas , Química Verde , Enzimas Imobilizadas/química , Enzimas Imobilizadas/metabolismo , Química Verde/métodos , Nanoestruturas/química , Biodegradação Ambiental
10.
Biomimetics (Basel) ; 8(2)2023 Apr 17.
Artigo em Inglês | MEDLINE | ID: mdl-37092415

RESUMO

According to the American Cancer Society, breast cancer is the second largest cause of mortality among women after lung cancer. Women's death rates can be decreased if breast cancer is diagnosed and treated early. Due to the lengthy duration of manual breast cancer diagnosis, an automated approach is necessary for early cancer identification. This research proposes a novel framework integrating metaheuristic optimization with deep learning and feature selection for robustly classifying breast cancer from ultrasound images. The structure of the proposed methodology consists of five stages, namely, data augmentation to improve the learning of convolutional neural network (CNN) models, transfer learning using GoogleNet deep network for feature extraction, selection of the best set of features using a novel optimization algorithm based on a hybrid of dipper throated and particle swarm optimization algorithms, and classification of the selected features using CNN optimized using the proposed optimization algorithm. To prove the effectiveness of the proposed approach, a set of experiments were conducted on a breast cancer dataset, freely available on Kaggle, to evaluate the performance of the proposed feature selection method and the performance of the optimized CNN. In addition, statistical tests were established to study the stability and difference of the proposed approach compared to state-of-the-art approaches. The achieved results confirmed the superiority of the proposed approach with a classification accuracy of 98.1%, which is better than the other approaches considered in the conducted experiments.

11.
Heliyon ; 9(9): e19809, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37809959

RESUMO

Medical video watermarking is one of the beneficial and efficient tools to prohibit important patients' data from illicit enrollment and redistribution. In this paper, a new blind watermarking scheme has been proposed to improve the confidentiality, integrity, authenticity, and perceptual quality of a medical video with minimum distortion. The proposed scheme is based on 2D-DWT and dual Hessenberg-QR decomposition, where the input medical video is initially processed into frames. Then, the processed frames are transformed into sub-bands using 2D-DWT, followed by applying Hessenberg-QR decomposition on the selected wavelet HL2 sub-band. The watermark is scrambled via Arnold cat map to raise confidentiality and then concealed in the modified selected features. The watermark is extracted in a fully blind mode without referencing the original video, which reduces the extraction time. The proposed scheme maintained a fundamental tradeoff between robustness and visual imperceptibility compared to existing methods against many commonly encountered attacks. The visual imperceptibility has been evaluated using well-known metrics PSNR, SSIM, Q-index, and histogram analysis. The proposed scheme achieves a high PSNR value of (70.6899 dB) with minimal distortion and a high robustness level with an average NC value of (0.9998) and BER value of (0.0023) while conserving a large payload capacity. The obtained results show superior performance over similar video watermarking methods. The limitation of this scheme is the elapsed time during the embedding process since we utilized dual Hessenberg-QR decomposition. One possible solution to reduce time consumption is simple decompositions like bound-constrained SVM or similar decompositions.

12.
Biomimetics (Basel) ; 8(3)2023 Jul 20.
Artigo em Inglês | MEDLINE | ID: mdl-37504209

RESUMO

Wind patterns can change due to climate change, causing more storms, hurricanes, and quiet spells. These changes can dramatically affect wind power system performance and predictability. Researchers and practitioners are creating more advanced wind power forecasting algorithms that combine more parameters and data sources. Advanced numerical weather prediction models, machine learning techniques, and real-time meteorological sensor and satellite data are used. This paper proposes a Recurrent Neural Network (RNN) forecasting model incorporating a Dynamic Fitness Al-Biruni Earth Radius (DFBER) algorithm to predict wind power data patterns. The performance of this model is compared with several other popular models, including BER, Jaya Algorithm (JAYA), Fire Hawk Optimizer (FHO), Whale Optimization Algorithm (WOA), Grey Wolf Optimizer (GWO), and Particle Swarm Optimization (PSO)-based models. The evaluation is done using various metrics such as relative root mean squared error (RRMSE), Nash Sutcliffe Efficiency (NSE), mean absolute error (MAE), mean bias error (MBE), Pearson's correlation coefficient (r), coefficient of determination (R2), and determination agreement (WI). According to the evaluation metrics and analysis presented in the study, the proposed RNN-DFBER-based model outperforms the other models considered. This suggests that the RNN model, combined with the DFBER algorithm, predicts wind power data patterns more effectively than the alternative models. To support the findings, visualizations are provided to demonstrate the effectiveness of the RNN-DFBER model. Additionally, statistical analyses, such as the ANOVA test and the Wilcoxon Signed-Rank test, are conducted to assess the significance and reliability of the results.

13.
Bioengineering (Basel) ; 10(4)2023 Mar 24.
Artigo em Inglês | MEDLINE | ID: mdl-37106593

RESUMO

BACKGROUND: Bio-signals are the essential data that smart healthcare systems require for diagnosing and treating common diseases. However, the amount of these signals that need to be processed and analyzed by healthcare systems is huge. Dealing with such a vast amount of data presents difficulties, such as the need for high storage and transmission capabilities. In addition, retaining the most useful clinical information in the input signal is essential while applying compression. METHODS: This paper proposes an algorithm for the efficient compression of bio-signals for IoMT applications. This algorithm extracts the features of the input signal using block-based HWT and then selects the most important features for reconstruction using the novel COVIDOA. RESULTS: We utilized two different public datasets for evaluation: MIT-BIH arrhythmia and EEG Motor Movement/Imagery, for ECG and EEG signals, respectively. The proposed algorithm's average values for CR, PRD, NCC, and QS are 18.06, 0.2470, 0.9467, and 85.366 for ECG signals and 12.6668, 0.4014, 0.9187, and 32.4809 for EEG signals. Further, the proposed algorithm shows its efficiency over other existing techniques regarding processing time. CONCLUSIONS: Experiments show that the proposed method successfully achieved a high CR while maintaining an excellent level of signal reconstruction in addition to its reduced processing time compared with the existing techniques.

14.
Biomimetics (Basel) ; 8(4)2023 Aug 07.
Artigo em Inglês | MEDLINE | ID: mdl-37622956

RESUMO

Parkinson's disease (PD) affects a large proportion of elderly people. Symptoms include tremors, slow movement, rigid muscles, and trouble speaking. With the aging of the developed world's population, this number is expected to rise. The early detection of PD and avoiding its severe consequences require a precise and efficient system. Our goal is to create an accurate AI model that can identify PD using human voices. We developed a transformer-based method for detecting PD by retrieving dysphonia measures from a subject's voice recording. It is uncommon to use a neural network (NN)-based solution for tabular vocal characteristics, but it has several advantages over a tree-based approach, including compatibility with continuous learning and the network's potential to be linked with an image/voice encoder for a more accurate multi modal solution, shifting SOTA approach from tree-based to a neural network (NN) is crucial for advancing research in multimodal solutions. Our method outperforms the state of the art (SOTA), namely Gradient-Boosted Decision Trees (GBDTs), by at least 1% AUC, and the precision and recall scores are also improved. We additionally offered an XgBoost-based feature-selection method and a fully connected NN layer technique for including continuous dysphonia measures, in addition to the solution network. We also discussed numerous important discoveries relating to our suggested solution and deep learning (DL) and its application to dysphonia measures, such as how a transformer-based network is more resilient to increased depth compared to a simple MLP network. The performance of the proposed approach and conventional machine learning techniques such as MLP, SVM, and Random Forest (RF) have also been compared. A detailed performance comparison matrix has been added to this article, along with the proposed solution's space and time complexity.

15.
Heliyon ; 9(7): e17622, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37424589

RESUMO

The Internet of Things (IoT) is a network of smart gadgets that are connected through the Internet, including computers, cameras, smart sensors, and mobile phones. Recent developments in the industrial IoT (IIoT) have enabled a wide range of applications, from small businesses to smart cities, which have become indispensable to many facets of human existence. In a system with a few devices, the short lifespan of conventional batteries, which raises maintenance costs, necessitates more replacements and has a negative environmental impact, does not present a problem. However, in networks with millions or even billions of devices, it poses a serious problem. The rapid expansion of the IoT paradigm is threatened by these battery restrictions, thus academics and businesses are now interested in prolonging the lifespan of IoT devices while retaining optimal performance. Resource management is an important aspect of IIoT because it's scarce and limited. Therefore, this paper proposed an efficient algorithm based on federated learning. Firstly, the optimization problem is decomposed into various sub-problems. Then, the particle swarm optimization algorithm is deployed to solve the energy budget. Finally, a communication resource is optimized by an iterative matching algorithm. Simulation results show that the proposed algorithm has better performance as compared with existing algorithms.

16.
Bioengineering (Basel) ; 10(7)2023 Jul 24.
Artigo em Inglês | MEDLINE | ID: mdl-37508907

RESUMO

This study aims to develop a predictive model for SARS-CoV-2 using machine-learning techniques and to explore various feature selection methods to enhance the accuracy of predictions. A precise forecast of the SARS-CoV-2 respiratory infections spread can help with efficient planning and resource allocation. The proposed model utilizes stochastic regression to capture the virus transmission's stochastic nature, considering data uncertainties. Feature selection techniques are employed to identify the most relevant and informative features contributing to prediction accuracy. Furthermore, the study explores the use of neighbor embedding and Sammon mapping algorithms to visualize high-dimensional SARS-CoV-2 respiratory infection data in a lower-dimensional space, enabling better interpretation and understanding of the underlying patterns. The application of machine-learning techniques for predicting SARS-CoV-2 respiratory infections, the use of statistical measures in healthcare, including confirmed cases, deaths, and recoveries, and an analysis of country-wise dynamics of the pandemic using machine-learning models are used. Our analysis involves the performance of various algorithms, including neural networks (NN), decision trees (DT), random forests (RF), the Adam optimizer (AD), hyperparameters (HP), stochastic regression (SR), neighbor embedding (NE), and Sammon mapping (SM). A pre-processed and feature-extracted SARS-CoV-2 respiratory infection dataset is combined with ADHPSRNESM to form a new orchestration in the proposed model for a perfect prediction to increase the precision of accuracy. The findings of this research can contribute to public health efforts by enabling policymakers and healthcare professionals to make informed decisions based on accurate predictions, ultimately aiding in managing and controlling the SARS-CoV-2 pandemic.

17.
Biomimetics (Basel) ; 8(3)2023 Jun 26.
Artigo em Inglês | MEDLINE | ID: mdl-37504158

RESUMO

Breast cancer is one of the most common cancers in women, with an estimated 287,850 new cases identified in 2022. There were 43,250 female deaths attributed to this malignancy. The high death rate associated with this type of cancer can be reduced with early detection. Nonetheless, a skilled professional is always necessary to manually diagnose this malignancy from mammography images. Many researchers have proposed several approaches based on artificial intelligence. However, they still face several obstacles, such as overlapping cancerous and noncancerous regions, extracting irrelevant features, and inadequate training models. In this paper, we developed a novel computationally automated biological mechanism for categorizing breast cancer. Using a new optimization approach based on the Advanced Al-Biruni Earth Radius (ABER) optimization algorithm, a boosting to the classification of breast cancer cases is realized. The stages of the proposed framework include data augmentation, feature extraction using AlexNet based on transfer learning, and optimized classification using a convolutional neural network (CNN). Using transfer learning and optimized CNN for classification improved the accuracy when the results are compared to recent approaches. Two publicly available datasets are utilized to evaluate the proposed framework, and the average classification accuracy is 97.95%. To ensure the statistical significance and difference between the proposed methodology, additional tests are conducted, such as analysis of variance (ANOVA) and Wilcoxon, in addition to evaluating various statistical analysis metrics. The results of these tests emphasized the effectiveness and statistical difference of the proposed methodology compared to current methods.

18.
Biomimetics (Basel) ; 8(3)2023 Jul 16.
Artigo em Inglês | MEDLINE | ID: mdl-37504202

RESUMO

The virus that causes monkeypox has been observed in Africa for several years, and it has been linked to the development of skin lesions. Public panic and anxiety have resulted from the deadly repercussions of virus infections following the COVID-19 pandemic. Rapid detection approaches are crucial since COVID-19 has reached a pandemic level. This study's overarching goal is to use metaheuristic optimization to boost the performance of feature selection and classification methods to identify skin lesions as indicators of monkeypox in the event of a pandemic. Deep learning and transfer learning approaches are used to extract the necessary features. The GoogLeNet network is the deep learning framework used for feature extraction. In addition, a binary implementation of the dipper throated optimization (DTO) algorithm is used for feature selection. The decision tree classifier is then used to label the selected set of features. The decision tree classifier is optimized using the continuous version of the DTO algorithm to improve the classification accuracy. Various evaluation methods are used to compare and contrast the proposed approach and the other competing methods using the following metrics: accuracy, sensitivity, specificity, p-Value, N-Value, and F1-score. Through feature selection and a decision tree classifier, the following results are achieved using the proposed approach; F1-score of 0.92, sensitivity of 0.95, specificity of 0.61, p-Value of 0.89, and N-Value of 0.79. The overall accuracy of the proposed methodology after optimizing the parameters of the decision tree classifier is 94.35%. Furthermore, the analysis of variation (ANOVA) and Wilcoxon signed rank test have been applied to the results to investigate the statistical distinction between the proposed methodology and the alternatives. This comparison verified the uniqueness and importance of the proposed approach to Monkeypox case detection.

19.
Diagnostics (Basel) ; 13(12)2023 Jun 12.
Artigo em Inglês | MEDLINE | ID: mdl-37370932

RESUMO

INTRODUCTION: In public health, machine learning algorithms have been used to predict or diagnose chronic epidemiological disorders such as diabetes mellitus, which has reached epidemic proportions due to its widespread occurrence around the world. Diabetes is just one of several diseases for which machine learning techniques can be used in the diagnosis, prognosis, and assessment procedures. METHODOLOGY: In this paper, we propose a new approach for boosting the classification of diabetes based on a new metaheuristic optimization algorithm. The proposed approach proposes a new feature selection algorithm based on a dynamic Al-Biruni earth radius and dipper-throated optimization algorithm (DBERDTO). The selected features are then classified using a random forest classifier with its parameters optimized using the proposed DBERDTO. RESULTS: The proposed methodology is evaluated and compared with recent optimization methods and machine learning models to prove its efficiency and superiority. The overall accuracy of diabetes classification achieved by the proposed approach is 98.6%. On the other hand, statistical tests have been conducted to assess the significance and the statistical difference of the proposed approach based on the analysis of variance (ANOVA) and Wilcoxon signed-rank tests. CONCLUSIONS: The results of these tests confirmed the superiority of the proposed approach compared to the other classification and optimization methods.

20.
Biomimetics (Basel) ; 8(2)2023 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-37366836

RESUMO

Metamaterials have unique physical properties. They are made of several elements and are structured in repeating patterns at a smaller wavelength than the phenomena they affect. Metamaterials' exact structure, geometry, size, orientation, and arrangement allow them to manipulate electromagnetic waves by blocking, absorbing, amplifying, or bending them to achieve benefits not possible with ordinary materials. Microwave invisibility cloaks, invisible submarines, revolutionary electronics, microwave components, filters, and antennas with a negative refractive index utilize metamaterials. This paper proposed an improved dipper throated-based ant colony optimization (DTACO) algorithm for forecasting the bandwidth of the metamaterial antenna. The first scenario in the tests covered the feature selection capabilities of the proposed binary DTACO algorithm for the dataset that was being evaluated, and the second scenario illustrated the algorithm's regression skills. Both scenarios are part of the studies. The state-of-the-art algorithms of DTO, ACO, particle swarm optimization (PSO), grey wolf optimizer (GWO), and whale optimization (WOA) were explored and compared to the DTACO algorithm. The basic multilayer perceptron (MLP) regressor model, the support vector regression (SVR) model, and the random forest (RF) regressor model were contrasted with the optimal ensemble DTACO-based model that was proposed. In order to assess the consistency of the DTACO-based model that was developed, the statistical research made use of Wilcoxon's rank-sum and ANOVA tests.

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