Detalhe da pesquisa
1.
Attenuation of Streptozotocin-Induced Diabetic Neuropathic Allodynia by Flavone Derivative Through Modulation of GABA-ergic Mechanisms and Endogenous Biomarkers.
Neurochem Res
; 49(4): 980-997, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38170385
2.
Synthesis, biochemical and computational evaluations of novel bis-acylhydrazones of 2,2'-(1,1'-biphenyl)-4,4'-diylbis(oxy))di(acetohydrazide) as dual cholinesterase inhibitors.
Bioorg Chem
; 144: 107144, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38281382
3.
Carbonylbis(hydrazine-1-carbothioamide) derivatives as a new class of α-glucosidase inhibitors and their mechanistic insights via molecular docking and dynamic simulations.
Arch Pharm (Weinheim)
; 357(3): e2300604, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38148299
4.
Synthesis of 3-hydroxy-2-naphthohydrazide-based hydrazones and their implications in diabetic management via in vitro and in silico approaches.
Arch Pharm (Weinheim)
; 357(2): e2300544, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38013251
5.
Synthesis of the chromone-thiosemicarbazone scaffold as promising α-glucosidase inhibitors: An in vitro and in silico approach toward antidiabetic drug design.
Arch Pharm (Weinheim)
; : e2400140, 2024 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38687119
6.
A High Dose of Calcitriol Inhibits Glycolysis and M2 Macrophage Polarization in the Tumor Microenvironment by Repressing mTOR Activation: in vitro and Molecular Docking Studies.
Cell Physiol Biochem
; 57(2): 105-122, 2023 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37052042
7.
Green Chemistry Approach toward the Regioselective Synthesis of α,α-Disubstituted Allylic Amines.
J Org Chem
; 88(16): 11992-11999, 2023 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535841
8.
Synthesis of new phenoxymethylcoumarin clubbed 4-arylthiazolylhydrazines as α-glucosidase inhibitors and their kinetics and molecular docking studies.
Bioorg Chem
; 131: 106302, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36528921
9.
Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors.
Bioorg Chem
; 139: 106739, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37478545
10.
Blocking the major inflammatory pathways by newly synthesized thiadiazine derivatives via in-vivo, in-vitro and in-silico mechanism.
Bioorg Chem
; 140: 106760, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37647806
11.
Effect of glucocorticoids on the development of COVID-19-associated pulmonary aspergillosis: A meta-analysis of 21 studies and 5174 patients.
Mycoses
; 66(11): 941-952, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37551043
12.
Dynamic Repositioning of Aerial Base Stations for Enhanced User Experience in 5G and Beyond.
Sensors (Basel)
; 23(16)2023 Aug 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37631635
13.
Synthesis, biological evaluation, and molecular docking study of chromen-linked hydrazine carbothioamides as potent α-glucosidase inhibitors.
Drug Dev Res
; 84(5): 962-974, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37186392
14.
Isoxazole analogues of dibenzazepine as possible leads against ulcers and skin disease: In vitro and in silico exploration.
Saudi Pharm J
; 31(12): 101877, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38075546
15.
One pot domino synthesis of new 3,5-disubstituted-tetrahydro-2H-1,3,5-thiadiazine-2-thiones (THTTs) as anti-inflammatory and antinociceptive candidates: A proof from in-vivo to in-vitro and in-silico mechanistic studies.
Bioorg Chem
; 127: 105974, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780683
16.
Incensole derivatives from frankincense: Isolation, enhancement, synthetic modification, and a plausible mechanism of their anti-depression activity.
Bioorg Chem
; 126: 105900, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35671644
17.
Novel Bis-Schiff's base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach.
Bioorg Chem
; 128: 106058, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35917750
18.
New insights into development and mortality of COVID-19-associated pulmonary aspergillosis in a homogenous cohort of 1161 intensive care patients.
Mycoses
; 65(11): 1010-1023, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-35716344
19.
Synthesis of novel hybrid pharmacophore of N-((4-sulfamoylphenyl)carbamothioyl)alkanamides as potent carbonic anhydrase-II and 15-lipoxygenase inhibitors.
Drug Dev Res
; 83(3): 745-754, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34897776
20.
Design, Synthesis and Molecular Docking Study of Novel 3-Phenyl-ß-Alanine-Based Oxadiazole Analogues as Potent Carbonic Anhydrase II Inhibitors.
Molecules
; 27(3)2022 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164091