[Cytological parameters of bronchoalveolar lavage in patients with chronic obstructive bronchitis exposed to laser radiation of blood]. / Tsitologicheskie pokazateli bronkhoal'veoliarnogo lavazha u bol'nykh khronicheskim obstruktivnym bronkhitom pri provedenii lazernogo oblucheniia krovi.

AIM: Clinicocytological evaluation of efficacy of combined treatment of chronic obstructive bronchitis (COB) in exacerbation with application of laser radiation of blood. MATERIALS AND METHODS: Combined treatment with the use of He-Ne intravenous and transcutaneous radiation of blood was given to 32 patients with COB. 27 COB patients treated without blood irradiation served control. Mean age of the patients (39 males and 20 females) was 59 +/- 9.5 years. In addition to conventional methods of examination and control of the treatment effect, cytological and bacteriological tests of BAL precipitate smears were made. RESULTS: Combined COB treatment with the use of laser blood radiation has an antiinflammatory action, promotes normalization of mucociliary transport, activation of phagocytosis and immune defense, cleansing of bronchial tree, reduction of obstruction (by FEV per 1 s), effective management of exacerbations. Hospital stay decreased by 3-4 days. Blood irradiation has the advantages as a noninvasive method. CONCLUSION: Clinical, cytological and bacteriological tests, determination of FEV provide a significant assessment of treatment efficacy in dynamics and facilitate the choice of the most effective regimen for management of COB in exacerbation.

[The combined-action preparation Sipralinat in the treatment of suppurative diseases of the soft tissues and osteomyelitis of the bones of the foot]. / Preparat kombinirovannogo deistviia Sipralinat v lechenii gnoinykh zabolevanii miagkikh tkanei i osteomielita kostei stopa.

Sipralynate is a powder containing the broad spectrum antibiotic sisomicin, the enzyme protease C and the polymer carrier sodium alginate with a drainage capacity promoting wound regeneration. The clinical trials with sipralynate showed that it was highly efficient in the treatment of patients with suppurative infections of the soft tissues and ossa pedis osteomyelitis. The tolerance was good.

[Treatment of purulent postoperative wounds with collagen and immobilised gentamycin]. / Lechenie gnoínykh ran kollagenom s immobilizirovannym gentamitsinom.

The results of treatment of purulent postoperative wounds in 184 patients are discussed. All the patients were operated on urgently. Various destructive diseases of the abdominal cavity organs, complicated with peritonitis, were the indication for the surgery. The abdominal cavity was drained through laparatomic wound. The wounds became suppurative with subsequent diastasis of the wound edges. Microbiologic, cytologic and clinical tests were used to estimate effectiveness of the treatment with the use of collagen sponge with immobilised gentamycin. The method has provided fastening of the healing process and shortening of in-hospital stay.

[Cyclophosphane in the treatment of trophic ulcers of lower extremities with allergic and autoimmune components]. / Tsiklofosfan v lechenii troficheskikh iazv nizhnikh konechnostei s allergicheskim i autoimmunnym komponentov.

In 36 patients with varicose-trophic ulcers of the lower extremities with marked allergic and autoimmune components use of low frequency ultrasound through 0.02% solution of chlorhexidine and 0.2% cyclophosphamide made it possible to diminish allergic dermatitis and eczema after 5 or 7 procedures. The ulcers cleaned in 8-13 days (sometimes, in 14-18 days). In 27 patients surgical correction of venous blood flow was performed after the sanatation and autodermoplasty of the ulcers. There were no recurrences in the long-term period (up to 2 years).

[The polymer sorbent regenkur in the treatment of suppurative wounds]. / Polimernyi sorbent regenkur v lechenii gnoinykh ran.

Clinico-laboratory tests of the new Soviet polymer sorbent Regenkur obtained on the basis of rarely cross-linked cellulose ester were conducted on 60 patients with acute purulent diseases of the soft tissues in the surgical clinic, Sechenov Medical Academy. In treatment with sorbent applications the number of microorganisms reduced by several factors on the 3rd-5th day; on the average, the term of wound cleansing was 4.6 days, granulations appeared on day 4.3 and peripheral epithelialization on day 6.5. The duration of hospital stay decreased by one third. Advantages of the new sorbent over those of the well-known foreign analogue Debrizan were revealed.

[Diagnosis and surgical treatment of foot osteomyelitis]. / Osobennosti diagnostiki i khirurgicheskogo lecheniia osteomyelita stopy.

The article analyses the results of surgical treatment of 227 patients with osteomyelitis of the foot bones. The peculiarities of the course of the disease, determined by the anatomical and functional features and the concomitant pathological conditions, are evaluated. Comparative appraisal of various methods of examination showed the radionuclide method to be most informative. The peculiarities of surgical operations in pyoinflammatory diseases of the foot bones, which are due to the necessary preservation of a segment of the foot for subsequent correction, call for obligatory application of combined necrectomy and a complex of agents with polyfunctional activity in addition to the traditional mechanical methods of treatment of the bone defect. The results of complex treatment were good in 72%, satisfactory in 23%, and poor in 5% of patients.

[Effect of biologically active dressings of wounds on the course of the wound process]. / Vliianie biologicheski aktivnykh pereviazochnykh pokrytii ran na techenie ranevogo protsessa.

A comparative analysis of the effectiveness and expediency of the local application of collocyl (128 patients), trypsin immobilized on textile cellulose and kapron matrix (186 patients) and gauze bandage moistened with a solution of enzymes and 10% sodium chloride was made. It was shown that collocyl as well as trypsin modified gauze and kapron accelerated cleansing the wounds of nonviable tissues, decreased their infectivity, reduced intoxication of the organism and improved the course of the wound process.

[Comparative evaluation of the effectiveness of biologically active and regular drainage in the prevention of disorders of wound healing]. / Sravnitel'naia otsenka éffektivnosti biologicheski aktivnogo i obychnykh drenazhei v profilaktike narusheniia zazhivleniia ran.

An analysis of clinical material on 35 patients with pyo-inflammatory processes in soft tissues is presented which were treated using biologically active drains. The cytological and cytochemical investigations have shown that draining properties of the biologically active drains are much better than those of the chlorvinyl and silicon drains.

[Low-frequency ultrasonics in the treatment of trophic ulcers]. / Ispol'zovanie nizkochastotnogo ul'trazvuka v lechenii troficheskikh iazv.

The treatment of trophic ulcers by the low-frequency ultrasound results in destruction of the collagen fibres of the fibro-cicatricial tissue, reduces the bacterial dissemination, stimulates the growth of a new granulation tissue which allows to fulfill autodermoplasty .

[Debrisan in the treatment of purulent wounds]. / Debrizan v lechenii gnoinykh ran.

Debrisan was used for the treatment of purulent wounds in 125 patients with postinjection and paraossal phlegmons, postoperative suppurations and tropic ulcers. Debrisan was shown to be an effective agent for physical antiseptics which can shorten the time of wound debridement.

[The helium-neon laser in the treatment of suppurative wounds]. / Gelii-neonovyi lazer v lechenii gnoinykh ran.

Comparative results of the treatment of purulent wounds of soft tissues of different genesis by traditional methods of drug therapy in combination with the low intensity laser radiation of the red part of the optical spectrum in 274 patients are described. A reliably accelerated cleansing of the wound was achieved with a simultaneous growth of the granulation tissue and epithelization. No complications were noted.

[Trypsin, immobilized on a textile cellulose matrix, in the treatment of suppurative wounds of soft tissue]. / Immobilizovannyi na tekstil'noi tselliuloznoi matritse tripsin v lechenii gnoinykh ran miagkikh tkanei.

In the treatment of 328 patients trypsin immobilized on cellulose matrix was used in 110 patients, native enzymes were used in 148 patients and 70 patients were given means of physical antiseptics. The results have shown advantages of immobilized trypsin for the treatment of the wound process.