Detalhe da pesquisa
1.
New approaches to moderate CRISPR-Cas9 activity: Addressing issues of cellular uptake and endosomal escape.
Mol Ther
; 30(1): 32-46, 2022 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34091053
2.
Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing.
Nucleic Acids Res
; 49(4): 2390-2399, 2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33544854
3.
A SLC35C2 Transporter-Targeting Fluorescent Probe for the Selective Detection of B Lymphocytes Identified by SLC-CRISPRi and Unbiased Fluorescence Library Screening.
Angew Chem Int Ed Engl
; 61(36): e202202095, 2022 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789526
4.
Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection.
Genome Res
; 28(6): 859-868, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29712754
5.
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection.
J Biol Chem
; 292(25): 10664-10671, 2017 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28446605
6.
Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.
Genome Res
; 24(1): 132-41, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24253446
7.
Recent advances in CRISPR-based functional genomics for the study of disease-associated genetic variants.
Exp Mol Med
; 56(4): 861-869, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38556550
8.
Direct measurement of engineered cancer mutations and their transcriptional phenotypes in single cells.
Nat Biotechnol
; 2023 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37697151
9.
Single-cell multi-gene identification of somatic mutations and gene rearrangements in cancer.
NAR Cancer
; 5(3): zcad034, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37435532
10.
Microhomology-based choice of Cas9 nuclease target sites.
Nat Methods
; 11(7): 705-6, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24972169
11.
Single-cell characterization of CRISPR-modified transcript isoforms with nanopore sequencing.
Genome Biol
; 22(1): 331, 2021 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34872615
12.
Integrative single-cell analysis of allele-specific copy number alterations and chromatin accessibility in cancer.
Nat Biotechnol
; 39(10): 1259-1269, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34017141
13.
A Crucial Role of ACBD3 Required for Coxsackievirus Infection in Animal Model Developed by AAV-Mediated CRISPR Genome Editing Technique.
Viruses
; 13(2)2021 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33546322
14.
CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites.
Mol Ther Methods Clin Dev
; 20: 792-800, 2021 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33768124
15.
Target identification of mouse stem cell probe CDy1 as ALDH2 and Abcb1b through live-cell affinity-matrix and ABC CRISPRa library.
RSC Chem Biol
; 2(6): 1590-1593, 2021 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34977573
16.
CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells.
Comput Struct Biotechnol J
; 18: 1686-1694, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32670508
17.
Adenine base editors catalyze cytosine conversions in human cells.
Nat Biotechnol
; 37(10): 1145-1148, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31548727
18.
Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target.
Nat Commun
; 10(1): 1111, 2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30846702
19.
Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy.
Nat Biotechnol
; 36(6): 536-539, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29702637
20.
SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells.
Oncotarget
; 7(46): 75698-75711, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27708228