Detalhe da pesquisa
1.
Rational design of balanced dual-targeting antibiotics with limited resistance.
PLoS Biol
; 18(10): e3000819, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33017402
2.
Suboptimal Global Transcriptional Response Increases the Harmful Effects of Loss-of-Function Mutations.
Mol Biol Evol
; 38(3): 1137-1150, 2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33306797
3.
Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
Proc Natl Acad Sci U S A
; 115(31): E7293-E7302, 2018 07 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30012610
4.
Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance.
Proc Natl Acad Sci U S A
; 115(25): E5726-E5735, 2018 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29871954
5.
Rapid Evolution of Reduced Susceptibility against a Balanced Dual-Targeting Antibiotic through Stepping-Stone Mutations.
Antimicrob Agents Chemother
; 63(9)2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31235632
6.
Network-level architecture and the evolutionary potential of underground metabolism.
Proc Natl Acad Sci U S A
; 111(32): 11762-7, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25071190
7.
One in a million: flow cytometric sorting of single cell-lysate assays in monodisperse picolitre double emulsion droplets for directed evolution.
Anal Chem
; 86(5): 2526-33, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24517505
8.
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke.
Proc Natl Acad Sci U S A
; 107(15): 6799-804, 2010 Apr 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-20351242
9.
Effects of bowel cleansing on the composition of the gut microbiota in inflammatory bowel disease patients and healthy controls.
Therap Adv Gastroenterol
; 16: 17562848231174298, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37324319
10.
Characterization of antibiotic resistomes by reprogrammed bacteriophage-enabled functional metagenomics in clinical strains.
Nat Microbiol
; 8(3): 410-423, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36759752
11.
A single early introduction governed viral diversity in the second wave of SARS-CoV-2 epidemic in Hungary.
Virus Evol
; 8(2): veac069, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35996591
12.
Proteome-wide landscape of solubility limits in a bacterial cell.
Sci Rep
; 12(1): 6547, 2022 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35449391
13.
Functional Anatomical Changes in Ulcerative Colitis Patients Determine Their Gut Microbiota Composition and Consequently the Possible Treatment Outcome.
Pharmaceuticals (Basel)
; 13(11)2020 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33126430
14.
Chemical-genetic profiling reveals limited cross-resistance between antimicrobial peptides with different modes of action.
Nat Commun
; 10(1): 5731, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31844052
15.
Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota.
Nat Microbiol
; 4(3): 447-458, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559406
16.
Integrated evolutionary analysis reveals antimicrobial peptides with limited resistance.
Nat Commun
; 10(1): 4538, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31586049
17.
Underground metabolism: network-level perspective and biotechnological potential.
Curr Opin Biotechnol
; 49: 108-114, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28837944
18.
Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins.
Nat Struct Mol Biol
; 25(3): 279-288, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29434345
19.
Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides.
Nat Microbiol
; 3(6): 718-731, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29795541
20.
Ultrahigh-throughput discovery of promiscuous enzymes by picodroplet functional metagenomics.
Nat Commun
; 6: 10008, 2015 Dec 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26639611