Detalhe da pesquisa
1.
An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents.
Regul Toxicol Pharmacol
; 142: 105428, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37277058
2.
A 90-day drinking water study in mice to characterize early events in the cancer mode of action of 1,4-dioxane.
Regul Toxicol Pharmacol
; 119: 104819, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-33189748
3.
Frameshift mutagenesis and microsatellite instability induced by human alkyladenine DNA glycosylase.
Mol Cell
; 37(6): 843-53, 2010 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20347426
4.
Human health assessment for long-term oral ingestion of diethylene glycol.
Regul Toxicol Pharmacol
; 87 Suppl 2: S1-S20, 2017 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-28465071
5.
The distribution, fate, and effects of propylene glycol substances in the environment.
Rev Environ Contam Toxicol
; 232: 107-38, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24984837
6.
The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study.
Regul Toxicol Pharmacol
; 68(2): 212-21, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24378700
7.
Mode of action assessment for propylene dichloride as a human carcinogen.
Chem Biol Interact
; 382: 110382, 2023 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754223
8.
O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
Proc Natl Acad Sci U S A
; 106(2): 576-81, 2009 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-19124772
9.
Epigenetic screening in product safety assessment: are we there yet?
Toxicol Mech Methods
; 21(4): 298-311, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21495868
10.
Epigenetics and chemical safety assessment.
Mutat Res
; 705(2): 83-95, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20399890
11.
Considerations for the Use of Mutation as a Regulatory Endpoint in Risk Assessment.
Environ Mol Mutagen
; 61(1): 84-93, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31301246
12.
A highly sensitive and selective high pressure liquid chromatography with tandem mass spectrometry (HPLC/MS-MS) method for the direct peptide reactivity assay (DPRA).
J Pharmacol Toxicol Methods
; 94(Pt 2): 1-15, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30099091
13.
A toxicological review of the ethylene glycol series: Commonalities and differences in toxicity and modes of action.
Toxicol Lett
; 278: 66-83, 2017 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28689762
14.
Transcription promotes guanine to thymine mutations in the non-transcribed strand of an Escherichia coli gene.
DNA Repair (Amst)
; 4(7): 806-13, 2005 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15961353
15.
Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations.
Nucleic Acids Res
; 31(12): 2990-4, 2003 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12799424
16.
Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents.
Mutat Res Rev Mutat Res
; 767: 77-91, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27036068
17.
Repair of endogenous DNA base lesions modulate lifespan in mice.
DNA Repair (Amst)
; 21: 78-86, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24994062
18.
Transcriptional networks in S. cerevisiae linked to an accumulation of base excision repair intermediates.
PLoS One
; 2(11): e1252, 2007 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-18043759
19.
Transcription-dependent increase in multiple classes of base substitution mutations in Escherichia coli.
J Bacteriol
; 184(24): 6866-72, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12446637