Detalhe da pesquisa
1.
Transcription Factor MYB as Therapeutic Target: Current Developments.
Int J Mol Sci
; 25(6)2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38542205
2.
Natural Products with Antitumor Potential Targeting the MYB-C/EBPß-p300 Transcription Module.
Molecules
; 27(7)2022 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408476
3.
Activation of the oncogenic transcription factor B-Myb via multisite phosphorylation and prolyl cis/trans isomerization.
Nucleic Acids Res
; 47(1): 103-121, 2019 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30321399
4.
Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPß.
Biochim Biophys Acta Mol Cell Res
; 1864(7): 1349-1358, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28476645
5.
Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction.
Blood
; 127(9): 1173-82, 2016 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-26631113
6.
Helenalin Acetate, a Natural Sesquiterpene Lactone with Anti-inflammatory and Anti-cancer Activity, Disrupts the Cooperation of CCAAT Box/Enhancer-binding Protein ß (C/EBPß) and Co-activator p300.
J Biol Chem
; 291(50): 26098-26108, 2016 Dec 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27803164
7.
A conserved patch of hydrophobic amino acids modulates Myb activity by mediating protein-protein interactions.
Biochim Biophys Acta
; 1859(7): 914-21, 2016 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-27080133
8.
Programmed cell death 4 protein (Pdcd4) and homeodomain-interacting protein kinase 2 (Hipk2) antagonistically control translation of Hipk2 mRNA.
Biochim Biophys Acta
; 1853(7): 1564-73, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25820028
9.
An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4.
Nucleic Acids Res
; 42(17): 11107-18, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25190455
10.
PRMT4 is a novel coactivator of c-Myb-dependent transcription in haematopoietic cell lines.
PLoS Genet
; 9(3): e1003343, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23505388
11.
Interaction and cooperation of the CCAAT-box enhancer-binding protein ß (C/EBPß) with the homeodomain-interacting protein kinase 2 (Hipk2).
J Biol Chem
; 288(31): 22257-69, 2013 Aug 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23782693
12.
C/EBPß cooperates with MYB to maintain the oncogenic program of AML cells.
Oncotarget
; 14: 174-177, 2023 03 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36913305
13.
Multimodal 4-arylchromene derivatives with microtubule-destabilizing, anti-angiogenic, and MYB-inhibitory activities.
Cancer Drug Resist
; 6(1): 59-77, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37065868
14.
Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA.
J Biol Chem
; 286(50): 42855-62, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22033922
15.
Structure of the tandem MA-3 region of Pdcd4 protein and characterization of its interactions with eIF4A and eIF4G: molecular mechanisms of a tumor suppressor.
J Biol Chem
; 286(19): 17270-80, 2011 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21454508
16.
C/EBPß sustains the oncogenic program of AML cells by cooperating with MYB and co-activator p300 in a transcriptional module.
Exp Hematol
; 108: 8-15, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35032593
17.
Src-Family Protein Kinase Inhibitors Suppress MYB Activity in a p300-Dependent Manner.
Cells
; 11(7)2022 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35406726
18.
Characterization of the MYB-inhibitory potential of the Pan-HDAC inhibitor LAQ824.
BBA Adv
; 2: 100034, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-37082582
19.
A synthetic covalent ligand of the C/EBPß transactivation domain inhibits acute myeloid leukemia cells.
Cancer Lett
; 530: 170-180, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35077804
20.
A New Naphthopyran Derivative Combines c-Myb Inhibition, Microtubule-Targeting Effects, and Antiangiogenic Properties.
ACS Med Chem Lett
; 13(11): 1783-1790, 2022 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36385941