Detalhe da pesquisa
1.
DeepCubist: Molecular Generator for Designing Peptidomimetics based on Complex three-dimensional scaffolds.
J Comput Aided Mol Des
; 37(2): 107-115, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36462089
2.
Synthesis of Three-Dimensional (Di)Azatricyclododecene Scaffold and Its Application to Peptidomimetics.
Chemistry
; 27(46): 11888-11894, 2021 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34060167
3.
Design and synthesis of 14 and 15-membered macrocyclic scaffolds exhibiting inhibitory activities of hypoxia-inducible factor 1α.
Bioorg Med Chem
; 30: 115949, 2021 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33360196
4.
The novel inhibitor PRI-724 for Wnt/ß-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice.
Exp Lung Res
; 45(7): 188-199, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31298961
5.
A mimetic of the mSin3-binding helix of NRSF/REST ameliorates abnormal pain behavior in chronic pain models.
Bioorg Med Chem Lett
; 27(20): 4705-4709, 2017 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28927787
6.
A novel mRNA decay inhibitor abolishes pathophysiological cellular transition.
Cell Death Discov
; 8(1): 278, 2022 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35672286
7.
Involvement of activator protein-1 family members in ß-catenin and p300 association on the genome of PANC-1 cells.
Heliyon
; 8(2): e08890, 2022 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-35198763
8.
Development of Low-Molecular-Weight Compounds Targeting the Cancer-Associated KLF5 Transcription Factor.
ACS Med Chem Lett
; 13(4): 687-694, 2022 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450365
9.
Comprehensive exploration of chemical space using trisubstituted carboranes.
Sci Rep
; 11(1): 24101, 2021 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34916538
10.
E7386, a Selective Inhibitor of the Interaction between ß-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling.
Cancer Res
; 81(4): 1052-1062, 2021 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33408116
11.
Anti-tumor Activity of the Small Molecule Inhibitor PRI-724 Against ß-Catenin-activated Hepatocellular Carcinoma.
Anticancer Res
; 40(9): 5211-5219, 2020 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-32878809
12.
Identification of new agonists of urotensin-II from a cyclic peptide library.
Bioorg Med Chem
; 17(18): 6742-7, 2009 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19695883
13.
ß-catenin signaling inhibitors ICG-001 and C-82 improve fibrosis in preclinical models of endometriosis.
Sci Rep
; 9(1): 20056, 2019 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31882904
14.
Selective Inhibition of ß-Catenin/Co-Activator Cyclic AMP Response Element-Binding Protein-Dependent Signaling Prevents the Emergence of Hapten-Induced Atopic Dermatitis-Like Dermatitis.
Ann Dermatol
; 31(6): 631-639, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33911662
15.
mS-11, a mimetic of the mSin3-binding helix in NRSF, ameliorates social interaction deficits in a prenatal valproic acid-induced autism mouse model.
Pharmacol Biochem Behav
; 176: 1-5, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30419271
16.
Establishment of an intermittent cold stress model using Tupaia belangeri and evaluation of compound C737 targeting neuron-restrictive silencer factor.
Exp Anim
; 65(3): 285-92, 2016 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27041457
17.
Follow-up: Prospective compound design using the 'SAR Matrix' method and matrix-derived conditional probabilities of activity.
F1000Res
; 4: 75, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25949808
18.
Identification of structurally diverse growth hormone secretagogue agonists by virtual screening and structure-activity relationship analysis of 2-formylaminoacetamide derivatives.
J Med Chem
; 47(17): 4286-90, 2004 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15294000
19.
Deprotection of N(in)-formyl group on tryptophan by application of new reagent, 1,2-dimethylethylendiamine in aqueous solution.
Adv Exp Med Biol
; 611: 159-60, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19400139
20.
Deprotection of the indole (N(ind))-formyl (For) group on tryptophan employing a new reagent, N,N'-dimethylethylendiamine (DMEDA) in an aqueous solution.
Chem Pharm Bull (Tokyo)
; 57(2): 211-3, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19182415