Detalhe da pesquisa
1.
Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor.
J Pharmacol Exp Ther
; 361(2): 229-244, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28193636
2.
Structure-based design and development of (benz)imidazole pyridones as JAK1-selective kinase inhibitors.
Bioorg Med Chem Lett
; 26(7): 1803-8, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927423
3.
Dichotomous but stringent substrate selection by the dual-function Cdk7 complex revealed by chemical genetics.
Nat Struct Mol Biol
; 13(1): 55-62, 2006 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-16327805
4.
Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening.
Chem Biol
; 11(5): 703-11, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15157881
5.
Effects of a Hyaluronic Acid/Hydroxypropyl Guar Artificial Tear Solution on Protection, Recovery, and Lubricity in Models of Corneal Epithelium.
J Ocul Pharmacol Ther
; 31(8): 491-7, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26067908
6.
Measure, mine, model, and manipulate: the future for HTS and chemoinformatics?
Drug Discov Today
; 11(19-20): 863-5, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16997135
7.
The role of protein dynamics in increasing binding affinity for an engineered protein-protein interaction established by H/D exchange mass spectrometry.
Biochemistry
; 45(28): 8488-98, 2006 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16834322
8.
Discovery of O-GlcNAc transferase inhibitors.
J Am Chem Soc
; 127(42): 14588-9, 2005 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-16231908
9.
Inhibitor scaffolds as new allele specific kinase substrates.
J Am Chem Soc
; 124(41): 12118-28, 2002 Oct 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-12371851