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1.
Eur Arch Otorhinolaryngol ; 279(1): 267-273, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33973085

RESUMO

PURPOSE: This clinical trial aimed to investigate the effects of different nasal packing methods and transseptal suture technique on swallowing after septoplasty. METHODS: This randomized prospective study consists of 180 consecutive patients with septal deviation. All the patients underwent septoplasty. All the patients were randomly assigned to three groups. In group A, transseptal sutures were used for septal stabilization. In group B, both nasal passages were packed with Merocel tampons for septal stabilization. In group C, both nasal passages were packed with Doyle silicone splints for septal stabilization. For the evaluation of swallowing, the Eating Assessment Tool (EAT-10) questionnaire and a visual analog scale (VAS) were administered to all the patients preoperatively and on the second and seventh postoperative days. RESULTS: One hundred and twenty two of the patients (67.7%) were female and 58 of them (32.2%) were male. The mean age was 32.41 ± 12.37 years (range: 18-57 years). Both EAT-10 and VAS scores on the second postoperative day were significantly higher than the preoperative scores in all the groups (p < 0.05). The transseptal suture group had significantly lower EAT-10 and VAS scores on the second postoperative day than the Merocel packing and silicone packing groups (p < 0.05). Both EAT-10 and VAS scores on the postop 7th day significantly decreased in all groups compared to the postop second day (p < 0.05). CONCLUSIONS: Septoplasty affects swallowing, regardless of whether a tampon is applied. Transeptal suturing has a lesser effect on swallowing than other techniques. Although silicone packing is a less invasive method, it negatively affects swallowing, similar to Merocel packing. The transseptal suture technique is more comfortable than the other techniques in terms of swallowing function in the postoperative period.


Assuntos
Deglutição , Rinoplastia , Adulto , Feminino , Humanos , Masculino , Septo Nasal/cirurgia , Estudos Prospectivos , Técnicas de Sutura , Suturas , Adulto Jovem
2.
Eur Arch Otorhinolaryngol ; 279(4): 1937-1942, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34279733

RESUMO

PURPOSE: To investigate the effect of thymic stromal lymphopoietin on the development of chronic otitis media with effusion MATERIALS AND METHODS: This study was conducted on 40 patients who had adenoidectomy operation. The objects were divided into two groups. Group 1; adenoidectomy with chronic serous otitis media, group 2; adenoidectomy without chronic serous otitis media. Serum and tissue thymic stromal lymphopoietin levels were measured by ELISA. Serum and tissue TLSP levels, mast cell count, adenoid size were compared between the groups. RESULTS: Twenty-four (60%) of patients were female and 16 (40%) were male. Twenty patients (55%) had adenoid hypertrophy with chronic serous otitis media, and 18 (45%) had adenoid hypertrophy without chronic serous otitis media. The mean age of the patients was 6.21 ± 2.31 years. The mean mast cell count was significantly higher in group 1 compared with group 2 (p = 0.017). The mean tissue thymic stromal lymphopoietin measurement was also significantly higher in group 1 than group 2 (p = 0.023). However, there was no significant difference in regards to serum levels between the groups (p = 0.480). CONCLUSION: The number of mast cells as well as thymic stromal lymphopoietin levels in the adenoids of children was significantly high in the chronic serous otitis media patients. The release of thymic stromal lymphopoietin from the adenoid tissue plays a role in initiating and maintaining a local inflammatory reaction in the eustachian tube that may lead eventually to middle ear effusion in non-atopic patients.


Assuntos
Tonsila Faríngea , Otite Média com Derrame , Otite Média , Adenoidectomia , Criança , Pré-Escolar , Citocinas , Feminino , Humanos , Hipertrofia/cirurgia , Masculino , Otite Média/cirurgia , Otite Média com Derrame/cirurgia , Linfopoietina do Estroma do Timo
3.
Acta Odontol Scand ; 80(1): 44-50, 2022 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-34102953

RESUMO

OBJECTIVE: The lack of a valid and appropriate halitosis screening survey prompted us to develop and validate a simple, 15-item questionnaire to be used as a screening tool to score halitosis for the daily practise. METHODS: After calculating the sample size, 200 participants were included in the study. All participants filled a 15-item questionnaire with the subsequent measurements of halitosis through the organoleptic scoring system and a halimeter. The application of questionnaire and the halitosis measurements were repeated 15 days after the first control. RESULTS: Mann-Whitney's U test was statistically significant between the halimeter measurements and Halfins scores (p=.000, p<.05). ROC curve is drawn due to halitometer analyses. The cut-off point was determined such as Halfins scores greater than 14 indicated halitosis (65.75 sensitivity, 66.04 specificity). The content validation and concurrent validity were proven successful. CONCLUSIONS: A new halitosis-specific screening tool called Halfins was proven as a valid diagnostic tool for measuring halitosis in the present study. Nevertheless, we believe this questionnaire could be used as complementary tool for the diagnosis of halitosis, seeing as its use alone is not able to firmly conclude the presence of halitosis in all cases, an organoleptic test or VSC assessment would still be necessary.


Assuntos
Halitose , Testes Respiratórios , Halitose/diagnóstico , Humanos , Sensação , Compostos de Enxofre , Inquéritos e Questionários
4.
Sleep Breath ; 25(3): 1427-1432, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33236204

RESUMO

BACKGROUND: The aim of this study was to integrate the physical findings of drug-induced sleep endoscopy with snoring sound analysis in patients with obstructive sleep apnea/hypopnea syndrome (OSAS) and to compare the findings with previously published data. METHODS: This was a prospective, non-randomized study. Participants were all candidates for surgical treatment of OSAS and formed three groups, retropalatal (RP) obstructions, retrolingual (RL) obstructions, and multilevel (ML) obstructions. At the time of DISE, recordings of concurrent snoring sounds were made. Mean pitch frequency, peak sound frequency, and fundamental frequency (Fo) components were determined. RESULTS: A total of 55 participants had mean age 46.2 ± 7.3 years, mean BMI 30.0 ± 3.7 kg/m2, and included 11 women (20%). Differences in mean pitch frequency, Fo, and peak sound frequency were all statistically significant between the RP and RL (p = 0.001), between ML and RL (p = 0.025) but were not significantly different between RP and ML. Mean pitch frequency of RP was lower than RL, and ML frequency was between RL and RP. The sound analysis graphics revealed RP waves with sharp peaks and lower frequencies and RL with smooth curves and higher frequencies. ML showed irregular patterns. Mean pitch frequency of RL was always above 400 Hz, whereas RP was below this value. CONCLUSIONS: It is feasible to apply sound analysis to determine the site of obstruction during DISE. Combining the data may help surgeons make more accurate assessments of the pattern of the disease.


Assuntos
Obstrução das Vias Respiratórias/patologia , Apneia Obstrutiva do Sono/patologia , Ronco , Adulto , Endoscopia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Espectrografia do Som
5.
Am J Otolaryngol ; 42(5): 103010, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33862565

RESUMO

PURPOSE: Chronic rhinosinusitis (CRS) is one of the most common chronic diseases seen worldwide. Endoscopic sinus surgery (ESS) has become a widely accepted procedure for medically refractory chronic rhinosinusitis and nasal polyps. Prevention of revision surgery often depends on good wound healing and less adhesion formation. In recent years, the effects of platelet-rich fibrin (PRF) on tissue healing have been addressed in many surgical branches, especially for dental implant surgery and plastic surgery. METHODS: This prospective study was conducted with 50 patients who underwent endoscopic sinus surgery for the diagnosis of nasal polyposis. While the middle meatus in one nasal cavity was filled with PRF and supported with Nasopore, only Nasopore was used in the other nasal cavity middle meatus. The patients were followed up clinically at weeks 1, 2, 3, 4, 8, and 12 postoperatively. The assessor determined the presence of adhesion, crusting, bleeding, frontal ostium stenosis, granulation, and infection, and if present, the grades of these complications were scored according to a questionnaire. RESULTS: In our study, adhesion, infection, bleeding, granulation, and frontal ostium stenosis were less common in the PRF group, and a statistically significant difference was found between the groups. CONCLUSION: In our study, better results were obtained in terms of adhesion, infection, bleeding, granulation, and frontal ostium stenosis after ESS as a result of the effects of PRF on wound healing. The application of PRF is an inexpensive and easy procedure. PRF can be a good alternative to other types of tampons after ESS.


Assuntos
Endoscopia/métodos , Hemostasia , Pólipos Nasais/cirurgia , Procedimentos Cirúrgicos Nasais/métodos , Seios Paranasais/cirurgia , Fibrina Rica em Plaquetas , Ferida Cirúrgica/fisiopatologia , Ferida Cirúrgica/terapia , Tampões Cirúrgicos , Aderências Teciduais , Cicatrização , Adulto , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Fibrina Rica em Plaquetas/fisiologia , Estudos Prospectivos , Inquéritos e Questionários , Resultado do Tratamento
6.
Am J Otolaryngol ; 41(1): 102326, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31732303

RESUMO

OBJECTIVES: Chronic Subjective Tinnitus is a very highly prevalent disorder worldwide. There is no definitive treatment. The aim of this study is to investigate the efficacy of transcutaneous electrical nerve stimulation (TENS) applied to the auricula for treating tinnitus using the Depression Anxiety Stress Scales (DASS) and Tinnitus Handicap Inventory (THI). METHODS: The 60 patients were randomly divided into 3 groups of 20 patients. The first group (A) had one ear stimulated with TENS, and the second group (B) had both ears stimulated. Group C (placebo group) received no electrical or sound stimulation. All group patients received total of 10 sessions with a maximum of 4 days between the sessions. RESULTS: The THI and DASS scores decreased significantly after the treatment (p < 0.05). A significant difference was also observed between the groups after treatment (p < 0.05). While there was no difference between group A and B, it was shown that group C's post-treatment score was significantly higher than those of both groups (p < 0.05.) CONCLUSION: It is important to note that TENS has a therapeutic effect on subjective chronic tinnitus as well as a placebo effect.


Assuntos
Zumbido/terapia , Estimulação Elétrica Nervosa Transcutânea , Adulto , Ansiedade/psicologia , Doença Crônica , Depressão/psicologia , Avaliação da Deficiência , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Zumbido/psicologia
7.
J Craniofac Surg ; 31(6): 1731-1733, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32371711

RESUMO

OBJECTIVE: Balloon sinuplasty is being used worldwide, however the olfactory functions after balloon sinuplasty are underestimated. The authors aimed to study the effects of conventional endoscopic sinus surgery (ESS) compared to the balloon sinuplasty on olfactory function. MATERIALS AND METHODS: Forty-four subjects were randomly divided into 2 groups as ESS and balloon sinuplasty. The olfactory functions of each subject were recorded preoperatively and at the 1st, 3rd, 6th, and 12th months postoperatively. RESULTS: The initial assessments of olfaction were the same in both groups. After the surgery, the olfactory functions were significantly better in those of ESS group (P < 0.05). CONCLUSION: The olfactory function is preserved better in the conventional surgery compared to the balloon catheter dilation of the frontal sinus.


Assuntos
Seio Frontal/cirurgia , Olfato , Adulto , Dilatação , Endoscopia , Feminino , Seio Frontal/fisiopatologia , Humanos , Masculino , Período Pós-Operatório , Rinite/cirurgia , Cateteres Urinários
8.
J Craniofac Surg ; 31(5): 1327-1329, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32195846

RESUMO

BACKGROUND: Repair of the septal perforation is a challenging procedure and there are many different surgical techniques. In this study, the authors present a novel method which the authors use costal cartilage and costal perichondrium sandwich graft as an interposition graft with bilateral opposing mucoperichondrial flaps. PATIENTS AND METHODS: Fourteen patients (5 females, 9 males) underwent septal perforation repair. All surgeries were performed through an open approach septoplasty technique. The edges of the perforation were incised to excise the mucosa with a thickness of 2 mm. Bilateral mucoperichondrial flaps were raised. Then costal cartilage and costal perichondrium were harvested from the rib. The cartilage was divided into a smaller piece which is 2 mm thick and 1 cm wider than perforation size. The prepared cartilage was wrapped with perichondrium to obtain a sandwich graft. This sandwich graft was placed between the mucoperichondrial flaps, corresponding to the perforation. RESULTS: After 9 months of follow-up, 11 (78%) of the 14 perforations were completely closed. Failure of the repair was observed in 3 patients; 2 of the perforations were medium size and one perforation was large size. No complications occurred. CONCLUSION: Using costal cartilage and costal perichondrium sandwich graft is a novel and useful technique especially in large septal perforations. Considering that septum surgery has an important role in the etiology of septum perforation, this method provides a good graft source for both perforation closure and simultaneous rhinoplasty surgery.


Assuntos
Cartilagem Costal/cirurgia , Adulto , Feminino , Humanos , Masculino , Perfuração do Septo Nasal/cirurgia , Nariz/cirurgia , Rinoplastia , Retalhos Cirúrgicos/cirurgia , Resultado do Tratamento , Adulto Jovem
9.
J Craniofac Surg ; 31(4): e334-e337, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32176002

RESUMO

OBJECTIVE: To enable tongue incisions to be repaired more easily, rapidly, and practically, particularly in pediatric patients by using 2-octyl cyanoacrylate (OCA) tissue adhesive. METHODS: A single linear incision was made on the midline dorsal part of the tongue. Twenty-four rats were randomly divided into the four groups: Group 1 (n = 6), OCA healing at day 5; group 2 (n = 6), OCA healing at day 21; group 3 (n = 6), Vicryl healing at day 5; group 4 (n = 6), Vicryl healing at day 21. In groups 1 and 2, OCA was applied to the incision site. The incisions of the rats in groups 3 and 4 were closed using Vicryl sutures. Histopathological examination was compared between and within the groups at day 5 and 21. RESULTS: The operation duration was significantly shorter with OCA than with Vicryl sutures(P < 0.001). Regarding the histopathological results, there were no differences between group 1 and group 3 in epithelial regeneration, inflammation, fibroblastic activity, edema, presence of giant cells, fibrin deposition, ulceration, abscess formation, and granulation tissue. However, moderate infiltration of acute inflammatory cells was significantly more frequent in group 1 than in group 3. At day 5, the incidence of moderate foreign body residue was significantly higher in group 1 than in group 3. No difference was observed between group 2 and group 4 at day 21 (P > 0.05). CONCLUSION: OCA is a practical, rapid, and effective method for repairing tongue lacerations. Although infiltration by inflammatory cells and foreign bodies increased in the early period, the long-term results of OCA were indistinguishable from those of suturing.


Assuntos
Cianoacrilatos/farmacologia , Lacerações/patologia , Lesões dos Tecidos Moles/patologia , Suturas , Língua/patologia , Animais , Feminino , Lacerações/tratamento farmacológico , Lacerações/cirurgia , Procedimentos Neurocirúrgicos , Ratos , Ratos Sprague-Dawley , Lesões dos Tecidos Moles/tratamento farmacológico , Lesões dos Tecidos Moles/cirurgia , Língua/cirurgia
10.
J Craniofac Surg ; 30(3): e272-e275, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30817543

RESUMO

The aim of this study is to find the ideal solution and the optimum temperature to protect the viability of the cartilage graft. This randomized prospective study consists of 30 patients with septal deviation. All patients had septoplasty operation for chronic nasal obstruction. Ten strips of cartilages were prepared from each excised septum and then immersed in formalin, alcohol (96%), saline (0,9%), gentamicin (80 mg), and cefazolin sodium (Cezol 1gr) solutions in a total of 300 vials. Those vials were stored for 6 months at both +4°C and -18°C temperatures. Two groups were compared with each other. 22 cases were male (73%) and 8 patients were female (7%). The age range was between 20 and 48 (average 25.34 ±â€Š4.09 years). Parameters at +4°C; the cartilage volume was not significantly different among the solutions (P >0.05). Necrosis was significantly lower in the alcohol (46.7%) compared to other solutions (P = 0.001). Calcification was lower in the gentamicin group (56.7%). The loss of metachromasia was lower in the alcohol solutions (P = 0.000). Parameters at -18°C; the loss of metachromasia was higher in the gentamicin group (56.7%) than the other solutions (P = 0.003). The authors observed no significance in the rates of necrosis, calcification, metaplasia, inflammation, vascularity, or fibrosis among the solutions (P >0.05). Less necrosis and metachromosis loss in the alcohol solution indicated that alcohol was more suitable for preservation of the cartilage. In addition, temperature degree for the preservation of the cartilage did not show any significant differences.


Assuntos
Cartilagens Nasais/patologia , Obstrução Nasal/cirurgia , Septo Nasal/cirurgia , Soluções para Preservação de Órgãos , Preservação de Tecido/métodos , Adulto , Calcinose/etiologia , Cefazolina , Doença Crônica , Etanol , Feminino , Fibrose , Formaldeído , Gentamicinas , Humanos , Masculino , Metaplasia , Pessoa de Meia-Idade , Necrose , Estudos Prospectivos , Reoperação , Rinoplastia , Solução Salina , Temperatura , Adulto Jovem
11.
Aesthetic Plast Surg ; 43(3): 786-792, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30783722

RESUMO

INTRODUCTION: Nasal dorsum irregularities after rhinoplasty are still one of the most common complaints among both surgeons and patients. In this study, we used a new cross-linked hyaluronan (NCH) gel and blood mixture as the stabilisation scaffold. Diced cartilage combined with the NCH gel and blood mixture was used for nasal dorsum camouflage. PATIENTS AND METHODS: Fifty-two thin-skinned patients (29 females and 23 males) underwent primary rhinoplasty including nasal dorsum enhancement with diced cartilage combined with the NCH gel and blood mixture. The cartilage tissue was diced into small pieces; then, 1 cc NCH gel and blood were added into diced cartilage. The mixture was delivered onto the nasal dorsum via dorsal retractor. RESULTS: After 1 year of follow-up, there were no irregularities in the nasal dorsum area observed, nor any displacement or absorbance of the camouflage material. No complications occurred. CONCLUSION: The use of diced cartilage combined with the NCH gel and blood is an effective, simple and safe method for nasal dorsum camouflage in thin-skinned patients in rhinoplasty. The NCH gel within the mixed graft also reduces adhesions at the osteotomy lines. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .


Assuntos
Cartilagem/transplante , Ácido Hialurônico , Rinoplastia/métodos , Adulto , Sangue , Cartilagem/cirurgia , Feminino , Géis , Humanos , Ácido Hialurônico/administração & dosagem , Masculino , Pele/anatomia & histologia , Adulto Jovem
12.
J Craniofac Surg ; 29(3): e322-e325, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29485564

RESUMO

OBJECTIVE: To investigate effects of smoking cigarette on male and female larynges and compare them. METHOD: Eighteen adult Wistar Albino rats were included to study; 9 were male and 9 female. The exposure groups each contained 6 rats, and the control groups 3 rats. Six male constituted group 1 and 6 female constituted group 2. Group 1 and 3 were exposed to smoke. Group 2 and 4 were composed of 3 males and 3 females, respectively. Smoke from 10 cigarettes was delivered in each of the morning and afternoon daily for 1 month. At the end of 4 weeks, all rats were sacrificed and their larynges were evaluated histopathologically. RESULTS: Microscobic evaluation of epithelium of vocal folds revealed no significant difference between study groups. There was also no difference between study and control groups. Subepitelial tissue showed no difference between study groups but angiogenesis and inflammation were higher in study groups. Epithelial analysis of false vocal folds showed significant difference between study groups. Female epithelium showed more hyperplastic and metaplastic changes. CONCLUSION: Cigarette smoke damaged both the vocal folds and false vocal folds. The female false vocal folds were more susceptible to damage than the males.


Assuntos
Fumar Cigarros/efeitos adversos , Prega Vocal/efeitos dos fármacos , Animais , Feminino , Hiperplasia , Laringe/patologia , Masculino , Metaplasia , Ratos , Ratos Wistar , Fatores Sexuais , Prega Vocal/patologia
13.
J Craniofac Surg ; 28(8): 2139-2142, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28938325

RESUMO

OBJECTIVE: To investigate the effect of dexpanthenol-vitamin A (Nazalnem) ointment applied to the surface of silastic splints with an airway immediately after nasal septal surgery on postoperative complaints and nasal mucosa function. MATERIALS AND METHODS: The study enrolled 60 patients undergoing nasal septoplasty surgery. Group 1 (n = 30) received silastic splints with ointment containing dexpanthenol-vitamin A (Nazalnem), and Group 2 (n = 30), the control group, received silastic splints with vaseline. Of these patients, 2 patients from the Group 1 and 9 from the Group 2 were excluded.A thin layer of ointment was applied to the flat side of a silastic splint with an airway. The splints were removed on the second postoperative day. Patients were evaluated preoperatively and 1 and 2 weeks postoperatively using a visual analog scale and the Sino-Nasal Outcome test (SNOT-22). Mucociliary clearance (MCC) tests were performed at the same times. RESULTS: Visual analog scale for nasal crusting, nasal congestion, and foul odor was better in Group 1 than in Group 2 both at 1 week and at 2 weeks postoperatively (P < 0.05).The SNOT scores were significantly lower in Group 1 than in Group 2 at 1 week (P < 0.01), but did not differ at 2 weeks postoperatively (P > 0.05).Postoperatively, the MCC were insignificant between the groups and within the groups at 1 and 2 weeks (P > 0.05). CONCLUSION: Although Dexpanthenol-Vitamin A ointment had no direct effect on wound healing, it had significant effects on crusting, obstruction, and foul smell. However, silastic splints with dexpanthenol did not improve the MCC of the nose.


Assuntos
Dimetilpolisiloxanos/uso terapêutico , Septo Nasal/cirurgia , Ácido Pantotênico/análogos & derivados , Rinoplastia/métodos , Contenções , Vitamina A/uso terapêutico , Humanos , Depuração Mucociliar , Ácido Pantotênico/uso terapêutico , Resultado do Tratamento
14.
J Craniofac Surg ; 27(5): 1151-5, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27300450

RESUMO

OBJECTIVE: The aim of this study was to analyze the influence of deviated nasal septum (DNS) type on nasal mucociliary clearance, quality of life (QoL), olfactory function, and efficiency of nasal surgery (septoplasty with or without inferior turbinate reduction and partial middle turbinectomy). METHODS: Fifty patients (20 females and 30 males) with septal deviation were included in the study and were divided into 6 groups according to deviation type after examination by nasal endoscopy and paranasal computed tomography. The saccharin clearance test to evaluate the nasal mucociliary clearance time, Connecticut Chemosensory Clinical Research Center smell test for olfactory function, and sinonasal outcome test-22 (SNOT-22) for patient satisfaction were applied preoperatively and postoperatively at the sixth week after surgery. RESULT: Nasal mucociliary clearance, smell, and SNOT-22 scores were measured before surgery and at the sixth week following surgery. No significant difference was found in olfactory and SNOT-22 scores for any of the DNS types (both convex and concave sides) (P > 0.05). In addition, there was no difference in the saccharin clearance time (SCT) of the concave and convex sides (P > 0.05). According to the DNS type, the mean SCT of the convex sides showed no difference, but that of the concave sides showed a difference in types 3, 4, 5, and 6. These types had a prolonged SCT (P < 0.05). Olfactory scores revealed no difference postoperatively in types 5 and 6 but were decreased significantly in types 1 to 4 (P < 0.05). There was no significant difference in the healing of both the mucociliary clearance (MCC) and olfactory functions. SNOT-22 results showed a significant decrease in type 3. CONCLUSION: All DNS types disturb the QoL regarding nasal MCC and olfaction functions. MCC values, olfactory function, and QoL scores are similar among the DNS types. Both sides of the DNS types affect the MCC scores symmetrically. Septal surgery improves olfaction function and QoL at the sixth week following surgery but disturbs nasal MCC; thus, the sixth week is too early to assess nasal MCC.


Assuntos
Depuração Mucociliar/fisiologia , Septo Nasal/diagnóstico por imagem , Deformidades Adquiridas Nasais/cirurgia , Satisfação do Paciente , Qualidade de Vida , Rinoplastia/métodos , Olfato/fisiologia , Adolescente , Adulto , Endoscopia/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Septo Nasal/cirurgia , Deformidades Adquiridas Nasais/diagnóstico , Deformidades Adquiridas Nasais/fisiopatologia , Tomografia Computadorizada por Raios X
15.
Am J Otolaryngol ; 36(2): 230-4, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25554004

RESUMO

OBJECTIVE: The aim of this study was to assess zinc levels in tinnitus patients, and to evaluate the effects of zinc deficiency on tinnitus and hearing loss. METHODS: One-hundred patients, who presented to an outpatient clinic with tinnitus between June 2009 and 2014, were included in the study. Patients were divided into three groups according to age: Group I (patients between 18 and 30years of age); Group II (patients between 31 and 60years of age); and Group III (patients between 61 and 78years of age). Following a complete ear, nose and throat examination, serum zinc levels were measured and the severity of tinnitus was quantified using the Tinnitus Severity Index Questionnaire (TSIQ). Patients were subsequently asked to provide a subjective judgment regarding the loudness of their tinnitus. The hearing status of patients was evaluated by audiometry and high-frequency audiometry. An average hearing sensitivity was calculated as the mean value of hearing thresholds between 250 and 20,000Hz. Serum zinc levels between 70 and 120µg/dl were considered normal. The severity and loudness of tinnitus, and the hearing thresholds of the normal zinc level and zinc-deficient groups, were compared. RESULTS: Twelve of 100 (12%) patients exhibited low zinc levels. The mean age of the zinc-deficient group was 65.41±12.77years. Serum zinc levels were significantly lower in group III (p<0.01). The severity and loudness of tinnitus were greater in zinc-deficient patients (p=0.011 and p=0.015, respectively). Moreover, the mean thresholds of air conduction were significantly higher in zinc-deficient patients (p=0.000). CONCLUSION: We observed that zinc levels decrease as age increases. In addition, there was a significant correlation between zinc level and the severity and loudness of tinnitus. Zinc deficiency was also associated with impairments in hearing thresholds.


Assuntos
Percepção Sonora/fisiologia , Zumbido/sangue , Zumbido/fisiopatologia , Zinco/sangue , Zinco/deficiência , Adolescente , Adulto , Fatores Etários , Idoso , Assistência Ambulatorial , Análise de Variância , Audiometria de Tons Puros/métodos , Limiar Auditivo/fisiologia , Biomarcadores/sangue , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Medição de Risco , Sensibilidade e Especificidade , Índice de Gravidade de Doença , Fatores Sexuais , Inquéritos e Questionários , Zumbido/diagnóstico , Adulto Jovem
16.
J Craniofac Surg ; 26(1): 277-80, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25490571

RESUMO

OBJECTIVE: The aim of this study is to show the possible positive effect of coenzyme Q10 (Co Q10) on regenerating in facial palsy. MATERIALS AND METHODS: Sixteen female Sprague-Dawley albino rats were randomly divided into 2 groups as Co Q10 and control groups. Group Q10 (n = 8) received Co Q10 of 10 mg/kg/d intraperitoneally for 30 days, and group C (n = 8) received saline solution of 1 mL/d intraperitoneally once daily for 30 days. The right facial nerve stimulation thresholds were determined before crush, immediately after crush, and after 1 month.After determination of the thresholds, the crushed part of the facial nerve was then excised. All specimens were examined by a pathologist using a light microscope. RESULTS: No statistically significant difference in stimulation threshold was found between the Co Q10 and saline groups after crushing (P = 0.645). After 1 month of treatment, stimulation thresholds were significantly lower in both the Co Q10 and saline groups (Ps = 0.028 and 0.016). However, the Co Q10 group showed greater improvement than the saline group (P = 0.050).After 1 month of treatment, neither the Co Q10 group nor the saline group had reached the precrushing amplitude levels (Ps = 0.027 and 0.011).Significant differences were found in vascular congestion, macrovacuolization, and myelin thickness between the Co Q10 and control groups by light microscopy (P < 0.05). CONCLUSIONS: Although many treatment methods have been tried to accelerate facial nerve regeneration after trauma, a definitive method has not been found yet. Co Q for the treatment of acute facial paralysis is promising on both physiologic assessments and pathologic evaluation.


Assuntos
Antioxidantes/uso terapêutico , Traumatismos do Nervo Facial/tratamento farmacológico , Regeneração Nervosa/efeitos dos fármacos , Ubiquinona/análogos & derivados , Animais , Estimulação Elétrica , Complexo de Proteínas da Cadeia de Transporte de Elétrons/uso terapêutico , Traumatismos do Nervo Facial/patologia , Traumatismos do Nervo Facial/fisiopatologia , Paralisia Facial/tratamento farmacológico , Paralisia Facial/fisiopatologia , Feminino , Hiperemia/tratamento farmacológico , Hiperemia/patologia , Bainha de Mielina/efeitos dos fármacos , Bainha de Mielina/patologia , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Limiar Sensorial/efeitos dos fármacos , Ubiquinona/uso terapêutico , Vacúolos/efeitos dos fármacos
17.
J Craniofac Surg ; 26(3): 831-5, 2015 May.
Artigo em Inglês | MEDLINE | ID: mdl-25915681

RESUMO

OBJECTIVE: To project the surgical resuscitation methods that we apply to the lower part of the face and the eyes with the aim of preventing functional and psychological problems that can occur in patients with facial paralysis. MATERIALS AND METHODS: Twenty-two patients with facial nerve paralysis due to acoustic neuroma, trauma, cholesteatoma, and parotid carcinoma were included in this study. In the lower facial region, the temporal muscle was suspended to the lower lip. In the upper facial region, eyelid gold implantation was performed. The reanimation results of the upper and lower facial regions were graded as excellent, good, fair, and poor in consideration of the symmetry after rest and smile according to May classification in the third month after the surgery. RESULTS: The study group comprised 15 men (68.2%) and 5 women (31.8 %) (mean age, 63.82 ± 14.18 years; range, 8-78 years). Of the patients, 18.2% (n = 4) had acoustic neuroma, 40.9% (n = 9) had facial trauma, 27.3% (n = 6) had cholesteatoma, and 13.6% (n = 3) had parotid carcinoma.Reanimation techniques were applied to 40.9% (n = 9) of the patients during the first 2-4 years, whereas 59.1% (n = 13) of patients underwent surgery after 4 years.In a total of 17 patients (77.3%) who had lower lip intervention, 4 patients (23.5%) had excellent results, 7 patients (41.2%) had good results, and 6 patients (35.3%) had moderate results.In the 22 patients who underwent the eyelid procedure, 5 patients (22.7 %) had excellent results, 13 patients (59.1 %) had good results, and 3 patients (18.2 %) had moderate results. Poor results were not observed in any patient. CONCLUSION: Facial paralysis is a disease that causes serious functional and psychological problems in patients. Therefore, the choice of treatment method is dependent on the etiology, duration of paralysis, expectations of the patient, and experience of the surgeon. Being less invasive methods, obtaining immediate results, requiring single surgical stage, and having long-lasting results and dynamic muscle transfer and static suspension methods are preferred.


Assuntos
Expressão Facial , Paralisia Facial/reabilitação , Ritidoplastia/métodos , Sorriso , Músculo Temporal/cirurgia , Adolescente , Adulto , Idoso , Criança , Paralisia Facial/fisiopatologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Adulto Jovem
18.
J Craniofac Surg ; 25(6): 1971-4, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25377954

RESUMO

OBJECTIVES: The objective of this study was to evaluate head and neck masses with real-time elastography to differentiate malignant masses. MATERIALS AND METHODS: Between January 2011 and December 2012, a total of 51 patients with a palpable mass in the neck region were included in this study. Excisional histopathologic data were compared with elastographic results and Doppler ultrasonography. RESULTS: The study group comprised 27 males (52.9%) and 24 females (47.1%) (mean [SD] age, 41.47 [19.59] y; range, 4-80 y). Fourteen masses were malignant (27.5%) and 37 were benign (72.5%). Comparing the elastographic results of benign and malignant masses, elastographic scores of the malignant masses were significantly higher than those of the benign masses (P < 0.005).The elastographic scores were divided into 2 groups: 34 (91.9%) patients with the diagnosis of benign mass had the score of 1 to 2, whereas 9 (64.3%) patients with the diagnosis of malignant cases had the score of 3 to 4. There was a significant difference between the groups (P < 0.005).However, 2 squamous cell carcinomas (28.6%) and 1 lymphoma (8.1%) were diagnosed with an elastographic score of 1 (Table 2). This showed that even an elastographic score of 1 was not enough to issue a diagnosis of benign masses. CONCLUSIONS: With improvements in the device and increased experience, this modality can become a useful tool for the routine use. However, this modality cannot be used for screening to merely provide additional information about the nature of the masses.


Assuntos
Técnicas de Imagem por Elasticidade/métodos , Neoplasias de Cabeça e Pescoço/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia/métodos , Carcinoma de Células Escamosas/diagnóstico por imagem , Criança , Pré-Escolar , Diagnóstico Diferencial , Endoscopia/métodos , Feminino , Neoplasias de Cabeça e Pescoço/patologia , Humanos , Laringoscopia , Linfoma/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Neoplasias das Glândulas Salivares/diagnóstico por imagem , Ultrassonografia Doppler , Adulto Jovem
19.
Acta Otolaryngol ; 144(7-8): 453-460, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39225671

RESUMO

BACKGROUND: Idiopathic intracranial hypertension (IIH) can affect both hearing and balance due to increased inner ear pressure. AIMS/OBJECTIVES: This study aimed to evaluate the impact of increased inner ear pressure on hearing and balance in patients with IIH using auditory and vestibular tests. MATERIAL AND METHODS: Twenty-four IIH patients and 28 healthy controls underwent oVEMP, pure tone audiometry, tympanometry, and acoustic reflex tests pre-lumbar punctures. IIH patients received acetazolamide. Pre- and post-treatment results, tinnitus, and vertigo scores were compared. Post-treatment oVEMP and audiometry results were compared between groups. RESULTS: Pre-treatment oVEMP showed a significant left N1 latency difference (p = 0.049). Post-treatment, left ear amplitude (p = 0.035) and both ear amplitude ratios (p = 0.044 and p = 0.047) increased significantly. Audiometry had no significant changes (p < 0.05). Tinnitus and vertigo scores decreased significantly (p ≤ 0.001). CONCLUSION: Prolonged oVEMP latency suggests IIH may impact the brain stem and vestibular nerve, while increased amplitude values indicate peripheral vestibular involvement. IIH affects hearing across all frequencies, especially at 4000 Hz, impacting both hearing and balance. SIGNIFICANCE: Understanding the effects of IIH on auditory and vestibular functions can guide effective treatments, improving quality of life for patients by addressing both hearing and balance issues.


Assuntos
Pseudotumor Cerebral , Humanos , Adulto , Feminino , Masculino , Pseudotumor Cerebral/fisiopatologia , Pseudotumor Cerebral/diagnóstico , Pseudotumor Cerebral/terapia , Pseudotumor Cerebral/complicações , Audiometria de Tons Puros , Estudos de Casos e Controles , Acetazolamida/uso terapêutico , Zumbido/fisiopatologia , Zumbido/diagnóstico , Zumbido/terapia , Zumbido/etiologia , Pessoa de Meia-Idade , Testes de Impedância Acústica , Adulto Jovem , Vertigem/etiologia , Vertigem/diagnóstico , Vertigem/fisiopatologia , Vertigem/terapia
20.
ScientificWorldJournal ; 2013: 689087, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-24379749

RESUMO

OBJECTIVE: To investigate the compression of the vestibulocochlear nerve in the etiology of the tinnitus in the normal hearing ears with temporal bone computed tomography scans. METHODS: A prospective nonrandomized study of 30 bilateral tinnitus and 30 normal hearing patients enrolled in this study. RESULTS: A total of 60 patients (ages ranged from 16 to 87) were included. The tinnitus group comprised 11 males and 19 females (mean age 49,50 ± 12,008) and the control group comprised 6 males and 24 females (mean age 39,47 ± 12,544). Regarding the right and left internal acoustic canals measurements (inlet, midcanal, and outlet canal lengths), there were no significant differences between the measurements of the control and tinnitus groups (P > 0.005). There was no narrowness in the internal acoustic canal of the tinnitus group compared with the control group. High-frequency audiometric measurements of the right and left ears tinnitus group at 8000, 9000, 10000, 11200, 12500, 14000, 16000, and 18000 Hz frequencies were significantly lower than the control group thresholds (P < 0.05). There was high-frequency hearing loss in the tinnitus group. CONCLUSION: There were no anatomical differences in the etiology of tinnitus rather than physiological degeneration in the nerves.


Assuntos
Orelha Interna/diagnóstico por imagem , Audição , Osso Temporal/diagnóstico por imagem , Zumbido/diagnóstico por imagem , Tomografia por Raios X , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Audiometria de Tons Puros , Estudos de Casos e Controles , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Osso Temporal/patologia , Zumbido/diagnóstico , Zumbido/patologia , Adulto Jovem
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